The decade of exosomal long RNA species: an emerging cancer antagonist

[1]  I. Struman,et al.  Exploring the RNA landscape of endothelial exosomes , 2018, RNA.

[2]  Y. Zhang,et al.  Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer , 2018, Molecular Cancer.

[3]  Nam-Trung Nguyen,et al.  Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles. , 2018, Small.

[4]  Graça Raposo,et al.  Shedding light on the cell biology of extracellular vesicles , 2018, Nature Reviews Molecular Cell Biology.

[5]  R. J. Kelleher,et al.  Exosomes Associated with Human Ovarian Tumors Harbor a Reversible Checkpoint of T-cell Responses , 2018, Cancer Immunology Research.

[6]  Yanan Li,et al.  The role of exosomes derived from cerebrospinal fluid of spinal cord injury in neuron proliferation in vitro , 2018, Artificial cells, nanomedicine, and biotechnology.

[7]  R. Takahashi,et al.  Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis , 2018, Nature Communications.

[8]  Guo-ping Ding,et al.  Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profile in Pancreatic Cancer Derived Exosomes Treated Dendritic Cells by Microarray Analysis , 2018, Journal of Cancer.

[9]  Qin Jiang,et al.  Identification and Characterization of Circular RNAs as a New Class of Putative Biomarkers in Diabetes Retinopathy. , 2017, Investigative ophthalmology & visual science.

[10]  T. Ochiya,et al.  Emerging role of extracellular vesicles as a senescence-associated secretory phenotype: Insights into the pathophysiology of lung diseases. , 2017, Molecular aspects of medicine.

[11]  Bing Chen,et al.  exoRBase: a database of circRNA, lncRNA and mRNA in human blood exosomes , 2017, Nucleic Acids Res..

[12]  Alfredo Pulvirenti,et al.  miRandola 2017: a curated knowledge base of non-invasive biomarkers , 2017, Nucleic Acids Res..

[13]  V. S. Reddy,et al.  The HBx gene of hepatitis B virus can influence hepatic microenvironment via exosomes by transferring its mRNA and protein. , 2017, Virus research.

[14]  L. O’Driscoll,et al.  Resistance to HER2-targeted anti-cancer drugs is associated with immune evasion in cancer cells and their derived extracellular vesicles , 2017, Oncoimmunology.

[15]  A. Möller,et al.  Exosomes derived from mesenchymal non‐small cell lung cancer cells promote chemoresistance , 2017, International journal of cancer.

[16]  B. Nabet,et al.  Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer , 2017, Cell.

[17]  M. Gorospe,et al.  RNA in extracellular vesicles , 2017, Wiley interdisciplinary reviews. RNA.

[18]  W. Taylor,et al.  Exosomal Markers (CD63 and CD9) Expression Pattern Using Immunohistochemistry in Resected Malignant and Nonmalignant Pancreatic Specimens. , 2017, Pancreas.

[19]  Jun He,et al.  Circular RNAs and cancer. , 2017, Cancer letters.

[20]  Bo Zhang,et al.  Glioma cells enhance angiogenesis and inhibit endothelial cell apoptosis through the release of exosomes that contain long non-coding RNA CCAT2 , 2017, Oncology reports.

[21]  Lu Jiang,et al.  Suppression of endothelial cell migration by tumor associated macrophage-derived exosomes is reversed by epithelial ovarian cancer exosomal lncRNA , 2017, Cancer Cell International.

[22]  S. Fan,et al.  Exosomes containing differential expression of microRNA and mRNA in osteosarcoma that can predict response to chemotherapy , 2017, Oncotarget.

[23]  Raghu Kalluri,et al.  Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic Cancer , 2017, Nature.

[24]  Xin Luan,et al.  Engineering exosomes as refined biological nanoplatforms for drug delivery , 2017, Acta Pharmacologica Sinica.

[25]  Wei Liang,et al.  Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancer progression , 2017, Journal of Cancer Research and Clinical Oncology.

[26]  Tian Liu,et al.  Circles reshaping the RNA world: from waste to treasure , 2017, Molecular Cancer.

[27]  Y Liu,et al.  Glioma cells promote angiogenesis through the release of exosomes containing long non-coding RNA POU3F3. , 2017, European review for medical and pharmacological sciences.

[28]  A. Chávez-Reyes,et al.  International Journal of Molecular Sciences Exosomes: from Garbage Bins to Promising Therapeutic Targets , 2022 .

[29]  Wei Li,et al.  Extracellular vesicles-mediated noncoding RNAs transfer in cancer , 2017, Journal of Hematology & Oncology.

[30]  Amirhossein Sahebkar,et al.  Exosomes: Nanoparticulate tools for RNA interference and drug delivery , 2017, Journal of cellular physiology.

[31]  Yongjiang Zheng,et al.  Exosome-Based Cancer Therapy: Implication for Targeting Cancer Stem Cells , 2017, Front. Pharmacol..

[32]  Alissa M. Weaver,et al.  Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes , 2016, Scientific Reports.

[33]  L. Du,et al.  Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer , 2016, Oncotarget.

[34]  Zhen Wang,et al.  Exosomes in tumor microenvironment: novel transporters and biomarkers , 2016, Journal of Translational Medicine.

[35]  Wang Lq,et al.  Exosomes mediated transfer of lncRNA UCA1 results in increased tamoxifen resistance in breast cancer cells. , 2016 .

[36]  Kevin V. Morris,et al.  Extracellular vesicle associated long non-coding RNAs functionally enhance cell viability , 2016, Non-coding RNA research.

[37]  Lei Dong,et al.  Circulating Long RNAs in Serum Extracellular Vesicles: Their Characterization and Potential Application as Biomarkers for Diagnosis of Colorectal Cancer , 2016, Cancer Epidemiology, Biomarkers & Prevention.

[38]  M. Guan,et al.  Exosomal Long Noncoding RNAs are Differentially Expressed in the Cervicovaginal Lavage Samples of Cervical Cancer Patients , 2016, Journal of clinical laboratory analysis.

[39]  D. Hong,et al.  Exosome-mediated drug resistance in cancer: the near future is here , 2016, Therapeutic advances in medical oncology.

[40]  Jin Ding,et al.  Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA. , 2016, Cancer cell.

[41]  Alireza Ahadi,et al.  Long non-coding RNAs harboring miRNA seed regions are enriched in prostate cancer exosomes , 2016, Scientific Reports.

[42]  Kei-Hoi Cheung,et al.  Extending gene ontology in the context of extracellular RNA and vesicle communication , 2016, Journal of Biomedical Semantics.

[43]  Yan Li,et al.  Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs , 2016, Nature Communications.

[44]  Venkatareddy Nadithe,et al.  Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges , 2016, Acta pharmaceutica Sinica. B.

[45]  Chunyang Bao,et al.  Circular RNA expands its territory , 2016, Molecular & cellular oncology.

[46]  Jannetta S. Steyn,et al.  Circular RNA enrichment in platelets is a signature of transcriptome degradation. , 2016, Blood.

[47]  W. Suchorska,et al.  The role of exosomes in tumor progression and metastasis (Review). , 2016, Oncology reports.

[48]  Shivakumar Keerthikumar,et al.  ExoCarta: A Web-Based Compendium of Exosomal Cargo. , 2016, Journal of molecular biology.

[49]  Roy Parker,et al.  Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance , 2016, PloS one.

[50]  Claudia Berrondo,et al.  Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary Exosomes , 2016, PloS one.

[51]  Xi Yang,et al.  The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment , 2015, BioMed research international.

[52]  P. Jose,et al.  Plasma long non-coding RNA, CoroMarker, a novel biomarker for diagnosis of coronary artery disease. , 2015, Clinical science.

[53]  Haimin Li,et al.  Circular RNA: A new star of noncoding RNAs. , 2015, Cancer letters.

[54]  F. Dieli,et al.  CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA , 2015, Molecular Cancer.

[55]  S. Zhong,et al.  Exosomes in development, metastasis and drug resistance of breast cancer , 2015, Cancer science.

[56]  Jiang-xia Zhao,et al.  Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis , 2015, Cell Research.

[57]  Xiaohua Li,et al.  Intercellular transfer of messenger RNAs in multiorgan tumorigenesis by tumor cell-derived exosomes. , 2015, Molecular medicine reports.

[58]  U. Gezer,et al.  Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease , 2015, Front. Genet..

[59]  Kenji Takahashi,et al.  Sa1818 Extracellular Vesicle-Encapsulated Long Non-Coding RNA HULC Modulates Epithelial-Mesenchymal Transition in Human Pancreatic Cancer , 2015 .

[60]  Antonella Bongiovanni,et al.  EVpedia: a community web portal for extracellular vesicles research , 2015, Bioinform..

[61]  Li Yang,et al.  Regulation of circRNA biogenesis , 2015, RNA biology.

[62]  Y. Shao,et al.  Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer , 2015, Tumor Biology.

[63]  Raymond M. Schiffelers,et al.  Possibilities and limitations of current technologies for quantification of biological extracellular vesicles and synthetic mimics , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[64]  Jiyeon Han,et al.  PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritis , 2015, Clinical and Experimental Medicine.

[65]  Kei-Hoi Cheung,et al.  Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies , 2015, Journal of extracellular vesicles.

[66]  John S. Satterlee,et al.  The NIH Extracellular RNA Communication Consortium , 2015, Journal of extracellular vesicles.

[67]  George A Calin,et al.  Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. , 2014, Cancer cell.

[68]  Petar Glažar,et al.  circBase: a database for circular RNAs , 2014, RNA.

[69]  G. Calin,et al.  The fusion of two worlds: Non-coding RNAs and extracellular vesicles - diagnostic and therapeutic implications (Review) , 2014, International journal of oncology.

[70]  X. Breakefield,et al.  Extracellular RNA mediates and marks cancer progression. , 2014, Seminars in cancer biology.

[71]  M. Yáñez-Mó,et al.  Tetraspanins in Extracellular Vesicle Formation and Function , 2014, Front. Immunol..

[72]  U. Gezer,et al.  Long non‐coding RNAs with low expression levels in cells are enriched in secreted exosomes , 2014, Cell biology international.

[73]  D. Bartel,et al.  Expanded identification and characterization of mammalian circular RNAs , 2014, Genome Biology.

[74]  Tushar Patel,et al.  Involvement of Extracellular Vesicle Long Noncoding RNA (linc-VLDLR) in Tumor Cell Responses to Chemotherapy , 2014, Molecular Cancer Research.

[75]  M. Tewari,et al.  Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions , 2014, Nucleic acids research.

[76]  T. Patel,et al.  Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer , 2014, FEBS open bio.

[77]  Nikolaus Rajewsky,et al.  Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation , 2014, The EMBO journal.

[78]  K. Morris,et al.  The rise of regulatory RNA , 2014, Nature Reviews Genetics.

[79]  U. Gezer,et al.  Investigation of circulating lncRNAs in B-cell neoplasms. , 2014, Clinica chimica acta; international journal of clinical chemistry.

[80]  Elaine C. Campbell,et al.  Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway. , 2014, European journal of cancer.

[81]  J.-L. Huang,et al.  Characteristics of long non-coding RNA and its relation to hepatocellular carcinoma. , 2014, Carcinogenesis.

[82]  Giovanni Camussi,et al.  Cellular phenotype and extracellular vesicles: basic and clinical considerations. , 2014, Stem cells and development.

[83]  Jiao Ma,et al.  Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors , 2014, Science.

[84]  D. Davis,et al.  MicroRNAs Transfer from Human Macrophages to Hepato-Carcinoma Cells and Inhibit Proliferation , 2013, The Journal of Immunology.

[85]  M. V. Filatov,et al.  Exosomes are natural carriers of exogenous siRNA to human cells in vitro , 2013, Cell Communication and Signaling.

[86]  D. Ichikawa,et al.  Circulating long non-coding RNAs in plasma of patients with gastric cancer. , 2013, Anticancer research.

[87]  R. Bak,et al.  Managing microRNAs with vector-encoded decoy-type inhibitors. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

[88]  B. Bao,et al.  Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review , 2013, Cancer and Metastasis Reviews.

[89]  J. Dear,et al.  Urinary exosomes: A reservoir for biomarker discovery and potential mediators of intrarenal signalling , 2013, Proteomics.

[90]  Y. Gho,et al.  Proteomics, transcriptomics and lipidomics of exosomes and ectosomes , 2013, Proteomics.

[91]  Sebastian D. Mackowiak,et al.  Circular RNAs are a large class of animal RNAs with regulatory potency , 2013, Nature.

[92]  J. Kjems,et al.  Natural RNA circles function as efficient microRNA sponges , 2013, Nature.

[93]  Michael K. Slevin,et al.  Circular RNAs are abundant, conserved, and associated with ALU repeats. , 2013, RNA.

[94]  T. Whiteside Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes). , 2013, Biochemical Society transactions.

[95]  J. Lötvall,et al.  EVpedia: an integrated database of high-throughput data for systemic analyses of extracellular vesicles , 2013, Journal of extracellular vesicles.

[96]  P. Altevogt,et al.  Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation , 2012, PLoS biology.

[97]  R. Coffey,et al.  Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS* , 2012, Molecular & Cellular Proteomics.

[98]  J. Silke,et al.  The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells , 2012, Science Signaling.

[99]  Julia Christina Gross,et al.  Active Wnt proteins are secreted on exosomes , 2012, Nature Cell Biology.

[100]  M. Zöller,et al.  Toward tailored exosomes: the exosomal tetraspanin web contributes to target cell selection. , 2012, The international journal of biochemistry & cell biology.

[101]  S. Aliño,et al.  Cell-Free Circulating Plasma hTERT mRNA Is a Useful Marker for Prostate Cancer Diagnosis and Is Associated with Poor Prognosis Tumor Characteristics , 2012, PloS one.

[102]  MITSURU CHIBA,et al.  Exosomes secreted from human colorectal cancer cell lines contain mRNAs, microRNAs and natural antisense RNAs, that can transfer into the human hepatoma HepG2 and lung cancer A549 cell lines , 2012, Oncology reports.

[103]  A. Laganà,et al.  miRandola: Extracellular Circulating MicroRNAs Database , 2012, PloS one.

[104]  Charles Gawad,et al.  Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types , 2012, PloS one.

[105]  R. Schiffelers,et al.  Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes , 2012, Journal of extracellular vesicles.

[106]  Suresh Mathivanan,et al.  ExoCarta 2012: database of exosomal proteins, RNA and lipids , 2011, Nucleic Acids Res..

[107]  M. Wood,et al.  Exosome nanotechnology: An emerging paradigm shift in drug delivery , 2011, BioEssays : news and reviews in molecular, cellular and developmental biology.

[108]  Hamid Cheshmi Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers , 2011 .

[109]  Fátima Sánchez-Cabo,et al.  Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells , 2011, Nature communications.

[110]  J. Lötvall,et al.  Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages , 2011, Journal of Translational Medicine.

[111]  J. Lötvall,et al.  Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle RNA , 2010, PloS one.

[112]  J. Rinn,et al.  A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response , 2010, Cell.

[113]  Gerard Pasterkamp,et al.  Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. , 2010, Stem cell research.

[114]  Daehee Hwang,et al.  Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells , 2009, BMC Genomics.

[115]  S. Mathivanan,et al.  ExoCarta: A compendium of exosomal proteins and RNA , 2009, Proteomics.

[116]  Graça Raposo,et al.  Exosomes--vesicular carriers for intercellular communication. , 2009, Current opinion in cell biology.

[117]  Cicek Gercel-Taylor,et al.  MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. , 2008, Gynecologic oncology.

[118]  Petra Schwille,et al.  Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes , 2008, Science.

[119]  Riitta Lahesmaa,et al.  Exosomes with Immune Modulatory Features Are Present in Human Breast Milk1 , 2007, The Journal of Immunology.

[120]  H. Valadi,et al.  Cell to Cell Signalling via Exosomes Through esRNA , 2007, Cell adhesion & migration.

[121]  J. Lötvall,et al.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.

[122]  Aled Clayton,et al.  Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids , 2006, Current protocols in cell biology.

[123]  L. Zitvogel,et al.  Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial. , 2005, Blood cells, molecules & diseases.

[124]  Jung-Ah Cho,et al.  Exosomes: A new delivery system for tumor antigens in cancer immunotherapy , 2005, International journal of cancer.

[125]  Olivier Lantz,et al.  Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial , 2005, Journal of Translational Medicine.

[126]  R. Weissleder,et al.  Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

[127]  Martina Tinzl,et al.  DD3PCA3 RNA analysis in urine--a new perspective for detecting prostate cancer. , 2004, European urology.

[128]  C. Melief,et al.  B lymphocytes secrete antigen-presenting vesicles , 1996, The Journal of experimental medicine.

[129]  M. Adam,et al.  Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes , 1985, The Journal of cell biology.

[130]  P. Stahl,et al.  Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes , 1983, The Journal of cell biology.

[131]  E. Trams,et al.  Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. , 1981, Biochimica et biophysica acta.

[132]  M. Coca-Prados,et al.  Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells , 1979, Nature.

[133]  D. Riesner,et al.  Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[134]  T. Whiteside Exosomes in Cancer: Another Mechanism of Tumor-Induced Immune Suppression. , 2017, Advances in experimental medicine and biology.

[135]  Liangliang Xu,et al.  The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma , 2016, Journal of Cancer Research and Clinical Oncology.

[136]  T. Whiteside Tumor-Derived Exosomes and Their Role in Cancer Progression. , 2016, Advances in clinical chemistry.

[137]  L-Q Wang,et al.  Exosomes mediated transfer of lncRNA UCA1 results in increased tamoxifen resistance in breast cancer cells. , 2016, European review for medical and pharmacological sciences.

[138]  Shu Wang,et al.  Using artificial microRNA sponges to achieve microRNA loss-of-function in cancer cells. , 2015, Advanced drug delivery reviews.

[139]  Feng Li,et al.  The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva. , 2015, Clinical chemistry.