Studies of the Structure of Glutamate Receptor Ion Channels and the Mechanisms of Their Blockade by Organic Cations

[1]  M. Samoilova,et al.  Structural Characteristics of Ionotropic Glutamate Receptors as Identified by Channel Blockade , 2002, Neuroscience and Behavioral Physiology.

[2]  V. Gmiro,et al.  Different arrangement of hydrophobic and nucleophilic components of channel binding sites in N-methyl-d-aspartate and AMPA receptors of rat brain is revealed by channel blockade , 2000, Neuroscience Letters.

[3]  R. Nicoll,et al.  Synaptic kainate receptors , 2000, Current Opinion in Neurobiology.

[4]  M. Samoilova,et al.  Voltage‐dependent block of native AMPA receptor channels by dicationic compounds , 2000, British journal of pharmacology.

[5]  A. Sobolevsky,et al.  Probing of NMDA Channels with Fast Blockers , 1999, The Journal of Neuroscience.

[6]  M. Samoilova,et al.  Characterization of AMPA receptor populations in rat brain cells by the use of subunit-specific open channel blocking drug, IEM-1460 , 1999, Brain Research.

[7]  B. Zhorov,et al.  Intersegment hydrogen bonds as possible structural determinants of the N/Q/R site in glutamate receptors. , 1999, Biophysical journal.

[8]  M. Samoilova,et al.  The open channel blocking drug, IEM-1460, reveals functionally distinct α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors in rat brain neurons , 1999, Neuroscience.

[9]  M. Sheng,et al.  Glutamate Receptor Anchoring Proteins and the Molecular Organization of Excitatory Synapses , 1999, Annals of the New York Academy of Sciences.

[10]  R. Dingledine,et al.  The glutamate receptor ion channels. , 1999, Pharmacological reviews.

[11]  K. Williams,et al.  The selectivity filter of the N-methyl-D-aspartate receptor: a tryptophan residue controls block and permeation of Mg2+. , 1998, Molecular pharmacology.

[12]  B. Chait,et al.  The structure of the potassium channel: molecular basis of K+ conduction and selectivity. , 1998, Science.

[13]  A. Ferrer-Montiel,et al.  Structural determinants of the blocker binding site in glutamate and NMDA receptor channels , 1998, Neuropharmacology.

[14]  P. Usherwood,et al.  Block of open channels of recombinant AMPA receptors and native AMPA/kainate receptors by Adamantane derivatives , 1997, The Journal of physiology.

[15]  M. Samoilova,et al.  Channel blocking drugs as tools to study glutamate receptors in insect muscles and molluscan neurons , 1997, Invertebrate Neuroscience.

[16]  S. Cull-Candy,et al.  Single-Channel Properties of Recombinant AMPA Receptors Depend on RNA Editing, Splice Variation, and Subunit Composition , 1997, The Journal of Neuroscience.

[17]  B. Sakmann,et al.  Dimensions and ion selectivity of recombinant AMPA and kainate receptor channels and their dependence on Q/R site residues. , 1996, The Journal of physiology.

[18]  D. Wyllie,et al.  Single-channel currents from recombinant NM DANRla /NR2D receptors expressed in Xenopus oocytes , 1996, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[19]  R. Dingledine,et al.  Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins. , 1996, The Journal of pharmacology and experimental therapeutics.

[20]  S. Antonov,et al.  Voltage‐dependent interaction of open‐channel blocking molecules with gating of NMDA receptors in rat cortical neurons. , 1996, The Journal of physiology.

[21]  O. Krishtal,et al.  Comparative Patch‐clamp Studies with Freshly Dissociated Rat Hippocampal and Striatal Neurons on the NMDA Receptor Antagonistic Effects of Amantadine and Memantine , 1996, The European journal of neuroscience.

[22]  T. Isa,et al.  Spermine blocks synaptic transmission mediated by Ca2+-permeable AMPA receptors , 1996, Neuroreport.

[23]  B. Sakmann,et al.  Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS , 1995, Neuron.

[24]  B Sakmann,et al.  Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. , 1995, The Journal of physiology.

[25]  M. Mayer,et al.  Trapping of glutamate and glycine during open channel block of rat hippocampal neuron NMDA receptors by 9‐aminoacridine. , 1995, The Journal of physiology.

[26]  B. Sakmann,et al.  Dimensions of the narrow portion of a recombinant NMDA receptor channel. , 1995, Biophysical journal.

[27]  S. Antonov,et al.  Novel adamantane derivatives act as blockers of open ligand-gated channels and as anticonvulsants. , 1995, Molecular pharmacology.

[28]  P. Usherwood,et al.  Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins. , 1993, The Journal of pharmacology and experimental therapeutics.

[29]  H. Monyer,et al.  Argiotoxin detects molecular differences in AMPA receptor channels , 1993, Neuron.

[30]  R. Huganir,et al.  AMPA glutamate receptor subunits are differentially distributed in rat brain , 1993, Neuroscience.

[31]  R. Dingledine,et al.  Structural determinants of barium permeation and rectification in non- NMDA glutamate receptor channels , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[32]  T. Yamakura,et al.  Identification by mutagenesis of a Mg2+ -block site of the NMDA receptor channel , 1992, Nature.

[33]  Vladimir S. Vorobjev,et al.  Vibrodissociation of sliced mammalian nervous tissue , 1991, Journal of Neuroscience Methods.

[34]  Harold A. Scheraga,et al.  Structure and free energy of complex thermodynamic systems , 1988 .

[35]  U. Singh,et al.  A NEW FORCE FIELD FOR MOLECULAR MECHANICAL SIMULATION OF NUCLEIC ACIDS AND PROTEINS , 1984 .

[36]  L. Magazanik Blockade of ion channels as an approach to studying AMPA receptor subtypes , 2006, Neuroscience and Behavioral Physiology.

[37]  V. Ananthanarayanan,et al.  Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand. , 1996, Biophysical journal.

[38]  I. Módy,et al.  Actions of ketamine, phencyclidine and MK‐801 on NMDA receptor currents in cultured mouse hippocampal neurones. , 1991, The Journal of physiology.

[39]  Boris S. Zhorov,et al.  A vector method for calculating the derivatives of the energy of the atom-atom interactions of complex molecules with respect to generalized coordinates , 1981 .

[40]  H. Stoboy,et al.  DIVISION OF INSTRUMENTATION: PHYSICAL FITNESS TESTING METHODS AND CRITERIA* , 1968 .