Dependent Mice Is T Cell Autoantigen-Specific and Rat Insulin Promoter-mCD 80-Transgenic Low Dose Streptozotocin-Induced Diabetes in

[1]  D. Harlan,et al.  Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[2]  W. Deppert,et al.  References Subscriptions Permissions Email Alerts Relationship Among Immunodominance of Single , 2013 .

[3]  A. Müllbacher,et al.  The generation of memory antigen‐specific cytotoxic T cell responses by CD28/CD80 interactions in the absence of antigen , 1997, European journal of immunology.

[4]  望月 圭 B7/BB-1 Expression and Hepatitis Activity in Liver Tissues of Patients With Chronic Hepatitis C , 1997 .

[5]  D. Harlan,et al.  Protection against lethal toxic shock by targeted disruption of the CD28 gene , 1996, The Journal of experimental medicine.

[6]  S. Swain,et al.  Single cell analyses of cytokine production. , 1997, Current opinion in immunology.

[7]  P. Linsley,et al.  Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function , 1994, The Journal of experimental medicine.

[8]  C. June,et al.  CD28‐deficient mice generate an impaired Th2 response to Schistosoma mansoni infection , 1996, European journal of immunology.

[9]  J. Gribben,et al.  Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7 , 1991, The Journal of experimental medicine.

[10]  C. Janeway,et al.  Expression of the Co-stimulator Molecule B7–1 in Pancreatic β-Cells Accelerates Diabetes in the NOD Mouse , 1995, Diabetes.

[11]  J. Bluestone,et al.  CD28/B7 costimulation regulates autoimmune diabetes induced with multiple low doses of streptozotocin. , 1997, Journal of immunology.

[12]  C. Janeway,et al.  CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells , 1996, The Journal of experimental medicine.

[13]  Y. T. Kim,et al.  Immunologic Studies on the Induction of Diabetes in Experimental Animals: Cellular Basis for the Induction of Diabetes by Streptozotocin , 1984, Diabetes.

[14]  Y. Paterson,et al.  Identification of an autologous insulin B chain peptide as a target antigen for H-2Kb-restricted cytotoxic T lymphocytes , 1992, The Journal of experimental medicine.

[15]  H. Pircher,et al.  T cell priming versus T cell tolerance induced by synthetic peptides , 1995, The Journal of experimental medicine.

[16]  N. Sarvetnick,et al.  Transgenic mice expressing IFN-gamma in pancreatic beta-cells are resistant to streptozotocin-induced diabetes. , 1995, The American journal of physiology.

[17]  M. Oldstone,et al.  Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes , 1995, Journal of virology.

[18]  D. Harlan,et al.  Very-Low-Dose Streptozotocin Induces Diabetes in Insulin Promoter-mB7-1 Transgenic Mice , 1995, Diabetes.

[19]  R. Flavell,et al.  Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes. , 1995, Immunity.

[20]  K. Okumura,et al.  CD86 (B70/B7-2) on endothelial cells co-stimulates allogeneic CD4+ T cells. , 1995, International immunology.

[21]  T. Mak,et al.  CD28-deficient mice are highly resistant to collagen-induced arthritis. , 1999, Journal of immunology.

[22]  C. Thompson,et al.  CD28 is required for germinal center formation. , 1996, Journal of immunology.

[23]  S. Bonner-Weir,et al.  Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice. , 1993, The Journal of clinical investigation.

[24]  H. von Boehmer,et al.  Autoimmune insulitis and diabetes in the absence of antigen‐specific contact between T cells and β‐islet cells , 1999, European journal of immunology.

[25]  D. Hanahan,et al.  Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy , 1997, The Journal of experimental medicine.

[26]  A. Rossini,et al.  Genetic Influence of the Streptozotocin-induced Insulitis and Hyperglycemia , 1977, Diabetes.

[27]  Y. Matsuzawa,et al.  The NOD mouse. , 1994, Diabetes research and clinical practice.

[28]  J. Sidney,et al.  Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice , 1997, Journal of virology.

[29]  P. Linsley,et al.  Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations , 1992, The Journal of experimental medicine.

[30]  D. Wegmann The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus. , 1996, Current opinion in immunology.

[31]  H. Pircher,et al.  Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice , 1991, Cell.

[32]  C. June,et al.  Primary porcine endothelial cells express membrane-bound B7-2 (CD86) and a soluble factor that co-stimulate cyclosporin A-resistant and CD28-dependent human T cell proliferation. , 1996, International immunology.

[33]  A. Rossini,et al.  Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. , 1976, Science.

[34]  K. Haskins,et al.  Diabetogenic T-Cell Clones , 1996, Diabetes.

[35]  K. Haskins,et al.  Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. , 1990, Science.

[36]  C. Janeway,et al.  Signals and signs for lymphocyte responses , 1994, Cell.

[37]  J. Rotter,et al.  Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33. , 2000, Diabetes.

[38]  T. Mak,et al.  CD28 is not required for rejection of unmanipulated syngeneic and autologous tumors , 1997, European journal of immunology.

[39]  S. Tonegawa,et al.  CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis. , 1999, Journal of immunology.

[40]  W. Chick,et al.  Studies of streptozotocin-induced insulitis and diabetes. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[41]  T. Mak,et al.  Skin allograft rejection in CD28-deficient mice. , 1996, Transplantation.

[42]  W. Heath,et al.  Cytotoxic T lymphocyte activation by cross-priming. , 1999, Current opinion in immunology.

[43]  P. Linsley,et al.  Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[44]  R. Flavell,et al.  The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen. , 1994, Immunity.

[45]  E. Fuchs,et al.  CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. , 1996, Immunity.

[46]  J. Miller,et al.  Constitutive class I-restricted exogenous presentation of self antigens in vivo , 1996, The Journal of experimental medicine.

[47]  A. Rossini,et al.  Sex differences in the multiple-dose streptozotocin model of diabetes. , 1978, Endocrinology.

[48]  J. Bluestone,et al.  Absence of B7-dependent responses in CD28-deficient mice. , 1994, Immunity.

[49]  L. Orci,et al.  Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes , 1992, The Journal of experimental medicine.

[50]  H. Kolb,et al.  Genetic control of low-dose streptozotocin-induced autoimmune diabetes in mice. , 1983, Journal of immunology.

[51]  A. Monaco,et al.  An improved method for isolation of mouse pancreatic islets. , 1985, Transplantation.

[52]  P. Linsley,et al.  The role of the CD28 receptor during T cell responses to antigen. , 1993, Annual review of immunology.

[53]  D. Harlan,et al.  Inflammatory cytokines IFN-gamma plus TNF-alpha induce regulated expression of CD80 (B7-1) but not CD86 (B7-2) on murine fibroblasts. , 1997, Journal of immunology.

[54]  J. Kekow,et al.  Measurement of Rat Insulin: Enzyme-Linked Immunosorbent Assay With Increased Sensitivity, High Accuracy, and Greater Practicability Than Established Radioimmunoassay , 1988, Diabetes.

[55]  B Zheng,et al.  Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. , 1995, Journal of immunology.

[56]  K P Lee,et al.  Differential T cell costimulatory requirements in CD28-deficient mice. , 1993, Science.