Rapid diagnosis and intraoperative margin assessment of human lung cancer with fluorescence lifetime imaging microscopy

[1]  Miss A.O. Penney.  (b) , 1974, The New Yale Book of Quotations.

[2]  L. Gaboury,et al.  Steady state and time-resolved fluorescence properties of metastatic and non-metastatic malignant cells from different species. , 1995, Journal of photochemistry and photobiology. B, Biology.

[3]  B Palcic,et al.  Detection and localization of early lung cancer by fluorescence bronchoscopy , 2000, Cancer.

[4]  R. Lotan,et al.  Autofluorescence Microscopy of Fresh Cervical-Tissue Sections Reveals Alterations in Tissue Biochemistry with Dysplasia¶ , 2001, Photochemistry and photobiology.

[5]  N Ramanujam,et al.  Low Temperature Fluorescence Imaging of Freeze-trapped Human Cervical Tissues. , 2001, Optics express.

[6]  S. Madhuri,et al.  Native Fluorescence Spectroscopy of Blood Plasma in the Characterization of Oral Malignancy ¶ , 2003, Photochemistry and photobiology.

[7]  S. Lam,et al.  Near‐infrared Raman spectroscopy for optical diagnosis of lung cancer , 2003, International journal of cancer.

[8]  F. Detterbeck,et al.  Bronchial margins in lung cancer resection specimens: utility of frozen section and gross evaluation , 2004, Modern Pathology.

[9]  N. Ramanujam,et al.  Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH. , 2005, Cancer research.

[10]  B. Kozioł,et al.  Riboflavin as a Source of Autofluorescence in Eisenia fetida Coelomocytes , 2006, Photochemistry and photobiology.

[11]  U. Utzinger,et al.  Endoscopic optical coherence tomography and laser‐induced fluorescence spectroscopy in a murine colon cancer model , 2006, Lasers in surgery and medicine.

[12]  Suzanne C. Whiteman,et al.  Optical Coherence Tomography: Real-time Imaging of Bronchial Airways Microstructure and Detection of Inflammatory/Neoplastic Morphologic Changes , 2006, Clinical Cancer Research.

[13]  Klaus Suhling,et al.  Time-resolved fluorescence microscopy , 2007, SPIE Optics East.

[14]  Jens Eickhoff,et al.  In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia. , 2007, Journal of biomedical optics.

[15]  N. Ramanujam,et al.  In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia , 2007, Proceedings of the National Academy of Sciences.

[16]  R. Rouzier,et al.  Factors influencing the use and accuracy of frozen section diagnosis of epithelial ovarian tumors. , 2008, American journal of obstetrics and gynecology.

[17]  Frank Y. S. Chuang,et al.  Fluorescence lifetime imaging microscopy: in vivo application to diagnosis of oral carcinoma. , 2009, Optics letters.

[18]  L. Cantley,et al.  Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.

[19]  T. Gabrecht,et al.  In vivo time-resolved spectroscopy of the human bronchial early cancer autofluorescence. , 2009, Journal of biomedical optics.

[20]  Ina Pavlova,et al.  Multiphoton microscopy as a diagnostic imaging modality for lung cancer , 2010, BiOS.

[21]  Paritosh Pande,et al.  Biochemical Imaging of Human Atherosclerotic Plaques with Fluorescence Lifetime Angioscopy , 2010, Photochemistry and photobiology.

[22]  A. Heikal.  Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies. , 2010, Biomarkers in medicine.

[23]  E. Felip,et al.  Neutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancer , 2012, Clinical and Translational Oncology.

[24]  W. Webb,et al.  Multiphoton microscopy and microspectroscopy for diagnostics of inflammatory and neoplastic lung. , 2012, Journal of biomedical optics.

[25]  Yan Peng,et al.  Auto-fluorescence lifetime and light reflectance spectroscopy for breast cancer diagnosis: potential tools for intraoperative margin detection , 2012, Biomedical optics express.

[26]  Changli Wang,et al.  MiR-26a enhances metastasis potential of lung cancer cells via AKT pathway by targeting PTEN. , 2012, Biochimica et biophysica acta.

[27]  F. Wouters,et al.  Fluorescence lifetime imaging microscopy in the medical sciences , 2014, Protoplasma.

[28]  S. Xie,et al.  Real-time optical diagnosis for surgical margin in low rectal cancer using multiphoton microscopy , 2013, Surgical Endoscopy.

[29]  Stephen T. C. Wong,et al.  Multimodal non-linear optical imaging for label-free differentiation of lung cancerous lesions from normal and desmoplastic tissues. , 2013, Biomedical optics express.

[30]  A. J. Bain,et al.  Separating NADH and NADPH fluorescence in live cells and tissues using FLIM , 2014, Nature Communications.

[31]  Ben Tran,et al.  Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. , 2014, Journal of the National Cancer Institute.

[32]  M. Baker,et al.  Multiphoton fluorescence lifetime imaging microscopy reveals free-to-bound NADH ratio changes associated with metabolic inhibition. , 2014, Journal of biomedical optics.

[33]  K. O'Byrne,et al.  Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. , 2014, Biochimica et biophysica acta.

[34]  M. Tan,et al.  The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism. , 2015, Cancer letters.