Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage
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M. Michishita | M. Toyoda | T. Ishiwata | Y. Itakura | K. Hirabayashi | N. Nakamura | Norihiko Sasaki | F. Gomi | Kimimasa Takahashi | F. Hasegawa
[1] M. Toyoda,et al. Fetal bovine serum enlarges the size of human pancreatic cancer spheres accompanied by an increase in the expression of cancer stem cell markers. , 2019, Biochemical and biophysical research communications.
[2] M. Toyoda,et al. Comparison of functional glycans between cancer stem cells and normal stem cells. , 2019, Histology and histopathology.
[3] M. Toyoda,et al. Gangliosides Contribute to Vascular Insulin Resistance , 2019, International journal of molecular sciences.
[4] M. Toyoda,et al. H19 long non-coding RNA contributes to sphere formation and invasion through regulation of CD24 and integrin expression in pancreatic cancer cells , 2018, Oncotarget.
[5] T. Ishiwata,et al. Pancreatic cancer stem cells: features and detection methods , 2018, Pathology & Oncology Research.
[6] Hua Yu,et al. Erratum: JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance (Cell Metabolism (2018) 27(1) (136–150.e5)(S1550413117306691)(10.1016/j.cmet.2017.11.001)) , 2018 .
[7] M. Michishita,et al. Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis , 2018, Laboratory Investigation.
[8] Fumio Hasegawa,et al. Stemness and anti‐cancer drug resistance in ATP‐binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions , 2018, Cancer science.
[9] Hua Yu,et al. JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance. , 2018, Cell metabolism.
[10] M. Michishita,et al. Electron microscopic analysis of different cell types in human pancreatic cancer spheres. , 2017, Oncology letters.
[11] E. Chiricozzi,et al. Gangliosides in Membrane Organization. , 2018, Progress in molecular biology and translational science.
[12] Zack Z Wang,et al. Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis , 2017, Journal of cellular physiology.
[13] S. Mayor,et al. The mystery of membrane organization: composition, regulation and roles of lipid rafts , 2017, Nature Reviews Molecular Cell Biology.
[14] Hee-Jung Choi,et al. The function of cancer-shed gangliosides in macrophage phenotype: involvement with angiogenesis , 2016, Oncotarget.
[15] T. Ishiwata. Cancer stem cells and epithelial‐mesenchymal transition: Novel therapeutic targets for cancer , 2016, Pathology international.
[16] G. D’Angelo,et al. Glycosphingolipid–Protein Interaction in Signal Transduction , 2016, International journal of molecular sciences.
[17] K. Biswas,et al. Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway. , 2016, Biochimica et biophysica acta.
[18] A. Krasinskas,et al. A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas , 2015, The American journal of surgical pathology.
[19] Paul D. Smith,et al. MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft Model , 2015, Molecular Cancer Therapeutics.
[20] M. Toyoda,et al. Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells , 2015, The Journal of Biological Chemistry.
[21] D. Mahuran,et al. Liquid chromatography/electrospray ionisation-tandem mass spectrometry quantification of GM2 gangliosides in human peripheral cells and plasma. , 2014, Analytical biochemistry.
[22] Benjamin D. Smith,et al. Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States. , 2014, Cancer research.
[23] P. Delannoy,et al. How Do Gangliosides Regulate RTKs Signaling? , 2013, Cells.
[24] Yihui Liu,et al. Tumor gangliosides accelerate murine tumor angiogenesis , 2013, Angiogenesis.
[25] M. Toyoda,et al. Glycoconjugates and Related Molecules in Human Vascular Endothelial Cells , 2013, International journal of vascular medicine.
[26] K. Handa,et al. Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells , 2013, Proceedings of the National Academy of Sciences.
[27] B. Lupo,et al. The Plasma Membrane Sialidase NEU3 Regulates the Malignancy of Renal Carcinoma Cells by Controlling β1 Integrin Internalization and Recycling* , 2012, The Journal of Biological Chemistry.
[28] G. Hortobagyi,et al. Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis. , 2012, The Journal of clinical investigation.
[29] Y. Igarashi,et al. Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia , 2012, The Journal of Biological Chemistry.
[30] S. Akinaga,et al. Genetically engineered humanized anti‐ganglioside GM2 antibody against multiple organ metastasis produced by GM2‐expressing small‐cell lung cancer cells , 2011, Cancer science.
[31] R. Weinberg,et al. A Perspective on Cancer Cell Metastasis , 2011, Science.
[32] M. Nowak,et al. Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer , 2010, Nature.
[33] Kazuro Furukawa,et al. GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft‐localization of gangliosides in a melanoma cell line , 2010, Cancer science.
[34] J. M. Aerts,et al. Inhibition of Glycosphingolipid Synthesis Induces a Profound Reduction of Plasma Cholesterol and Inhibits Atherosclerosis Development in APOE*3 Leiden and Low-Density Lipoprotein Receptor−/− Mice , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[35] J. D'haese,et al. Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer. , 2009, Gastroenterology.
[36] Leslie H. Sobin,et al. TNM Classification of Malignant Tumours, 7th Edition , 2009 .
[37] A. Jemal,et al. Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.
[38] S. Hakomori,et al. Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. , 2008, Biochimica et biophysica acta.
[39] Seng H. Cheng,et al. Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes , 2007, Diabetes.
[40] M. Borner,et al. Successful challenge with the fully human EGFR antibody panitumumab following an infusion reaction with the chimeric EGFR antibody cetuximab. , 2007, Annals of oncology : official journal of the European Society for Medical Oncology.
[41] S. O’Rahilly,et al. Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity , 2007, Diabetes.
[42] Kazuro Furukawa,et al. Overexpressed GM1 Suppresses Nerve Growth Factor (NGF) Signals by Modulating the Intracellular Localization of NGF Receptors and Membrane Fluidity in PC12 Cells* , 2004, Journal of Biological Chemistry.
[43] C. Hollak,et al. Biochemistry of glycosphingolipid storage disorders: implications for therapeutic intervention. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[44] Kohei Miyazono,et al. TGF-β signalling from cell membrane to nucleus through SMAD proteins , 1997, Nature.
[45] S. Hakomori. Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. , 1996, Cancer research.
[46] L. Old,et al. Human monoclonal antibodies to glycolipids and other carbohydrate antigens: dissection of the humoral immune response in cancer patients. , 1989, Cancer research.
[47] L. Ulsh,et al. Immunosuppressive activity of human neuroblastoma tumor gangliosides , 1989, International journal of cancer.
[48] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[49] S. Kitada,et al. Gangliosides shed by tumor cells enhance tumor formation in mice. , 1987, The Journal of clinical investigation.
[50] A. Dell,et al. Glycosphingolipids of lectin-resistant mutants of the highly metastatic mouse tumor cell line, MDAY-D2. , 1987, Cancer research.
[51] L. Sobin,et al. TNM Classification of Malignant Tumours , 1987, UICC International Union Against Cancer.
[52] G. Zwingelstein,et al. Studies of a ganglioside fraction extracted from human malignant melanoma. , 1976, Biochimie.