Biometric investigation of changes in the anterior eye segment during accommodation

Non-invasive biometry of the anterior structures of the human eye can be performed with unprecedented precision of 8-10 microns and a resolution of approximately 9 microns by partial coherence interferometry, which has the potential to assess the effect of cycloplegia on the ocular components of the anterior eye segment, to further improve the precision to 1-2 microns by the use of these agents and to quantify the amount of residual accommodations in different states of cycloplegia. In addition, the anterior chamber depth, the thickness of the crystalline lens, their changes during accommodation, as well as the movement of the anterior and posterior lens pole during accommodation can be quantified objectively and accurately to investigate the mechanism of accommodation.

[1]  A J Adams,et al.  The effect of cycloplegia on measurement of the ocular components. , 1994, Investigative ophthalmology & visual science.

[2]  Martin S. Banks,et al.  Depth of focus, eye size and visual acuity , 1980, Vision Research.

[3]  F. W. Campbell,et al.  Effect of Focus on the Visual Response to a Sinusoidally Modulated Spatial Stimulus , 1965 .

[4]  I Lavery,et al.  Safe use of lasers. , 1978, Occupational health; a journal for occupational health nurses.

[5]  G. Weinstein,et al.  Psychotic reaction induced by cyclopentolate (Cyclogyl). Results of pilot study and a double-blind study. , 1963, American journal of ophthalmology.

[6]  E A Swanson,et al.  Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography. , 1995, Archives of ophthalmology.

[7]  W. G. Whitmore.  A biometric study of ocular changes during accommodation. , 1993, American journal of ophthalmology.

[8]  W. N. Charman,et al.  Pupil Diameter and the Depth-of-field of the Human Eye as Measured by Laser Speckle , 1977 .

[9]  C K Hitzenberger,et al.  Measurement of the axial length of cataract eyes by laser Doppler interferometry. , 1993, Investigative ophthalmology & visual science.

[10]  Francis Heed Adler,et al.  Adler's Physiology of the eye;: Clinical application , 1976 .

[11]  A. Fercher,et al.  In vivo optical coherence tomography. , 1993, American journal of ophthalmology.

[12]  H. Fledelius.  Accommodation and Juvenile Myopia , 1981 .

[13]  E A Swanson,et al.  Micrometer-scale resolution imaging of the anterior eye in vivo with optical coherence tomography. , 1994, Archives of ophthalmology.

[14]  Jane F. Koretz,et al.  Accommodation and presbyopia in the human eye—aging of the anterior segment , 1989, Vision Research.

[15]  N. Brown,et al.  The change in shape and internal form of the lens of the eye on accommodation. , 1973, Experimental eye research.

[16]  S. Pancharatnam.  Partial polarisation, partial coherence and their spectral description for polychromatic light—Part II , 1963 .

[17]  G. Bleeker.  Evaluation of Three Methods of Recording the Anterior Chamber Depth of the Eye , 1961 .

[18]  K. Awan.  Adverse systemic reactions of topical cyclopentolate hydrochloride. , 1976, Annals of ophthalmology.

[19]  Adolf Friedrich Fercher,et al.  Ophthalmic Laser Interferometry , 1986, Other Conferences.

[20]  F. Newell.  The American Journal of Ophthalmology , 1862, American journal of ophthalmology.

[21]  Harald Sattmann,et al.  Measurement of the anterior structures of the human eye by partial coherence interferometry , 1995, Other Conferences.

[22]  N. Brown,et al.  The shape of the lens equator. , 1974, Experimental eye research.

[23]  Christopher A. Cook,et al.  Aging of the human crystalline lens and anterior segment , 1994, Vision Research.

[24]  G. Glockler,et al.  Proceedings of the Indian Academy of Science. , 1939 .

[25]  H. Obstfeld,et al.  Optics in Vision , 1982, Visual Science and Engineering.

[26]  J M Thijssen,et al.  Intraocular lens power calculations: the optimal approach. , 1985, Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde.

[27]  Richard F. Brubaker,et al.  Adler's Physiology of the Eye , 1976 .

[28]  D. Albert,et al.  The effect of photodynamic action on corneal cells in tissue culture. , 1975, Experimental eye research.

[29]  C K Hitzenberger,et al.  Submicrometer precision biometry of the anterior segment of the human eye. , 1997, Investigative ophthalmology & visual science.

[30]  Awan Kj.  Adverse systemic reactions of topical cyclopentolate hydrochloride. , 1976 .

[31]  Campbell Fw.  A method for measuring the depth of field of the human eye. , 1954 .

[32]  J. Duker,et al.  Imaging of macular diseases with optical coherence tomography. , 1995, Ophthalmology.

[33]  Harald Sattmann,et al.  Measurement of the thickness of fundus layers by partial coherence tomography , 1995 .

[34]  C K Hitzenberger,et al.  Optical measurement of the axial eye length by laser Doppler interferometry. , 1991, Investigative ophthalmology & visual science.

[35]  A J Adams,et al.  The repeatability of measurement of the ocular components. , 1992, Investigative ophthalmology & visual science.

[36]  J. Fujimoto,et al.  Micron‐resolution ranging of cornea anterior chamber by optical reflectometry , 1991, Lasers in surgery and medicine.