Diet as a risk factor for peripheral arterial disease in the general population: the Edinburgh Artery Study.

The Edinburgh Artery Study included a cross-sectional survey of 1592 men and women (aged 55-74 y). One aim was to examine relationships between an indicator of peripheral arterial disease, the ankle brachial pressure index (ABPI), and dietary factors. Nutrient intake was derived from a food-frequency questionnaire. Higher frequency of consumption of fiber-containing foods was associated with greater mean ABPI in males and higher consumption of meat and meat products were significantly associated with low mean ABPI in males and females. In a multiple linear regression with ABPI as outcome and energy-adjusted nutrients as predictors, cereal fiber (P = 0.02) and alcohol (P = 0.04) were positively associated with the ABPI in males but not in females. Dietary vitamin E(alpha-tocopherol) intake was positively associated with ABPI (P = 0.04) independently of smoking and other nutrients. Dietary vitamin C intake was significantly related to ABPI (P = 0.006) only among those who had ever smoked.

[1]  W. P. Dixon,et al.  BMPD statistical software manual , 1988 .

[2]  P. Puska,et al.  Plasma Vitamins E and A Inversely Correlated to Mortality from Ischemic Heart Disease in Cross‐Cultural Epidemiology , 1989, Annals of the New York Academy of Sciences.

[3]  Meir J. Stampfer,et al.  Total energy intake: implications for epidemiologic analyses. , 1986, American journal of epidemiology.

[4]  H. Tunstall-Pedoe,et al.  Coronary Risk Factor and Lifestyle Variation across Scotland: Results from the Scottish Heart Health Study , 1989, Scottish medical journal.

[5]  H. Keen,et al.  SMOKING AND OTHER RISK FACTORS FOR CORONARY HEART-DISEASE IN BRITISH CIVIL SERVANTS , 1976, The Lancet.

[6]  R F Heller,et al.  Reducing blood cholesterol levels in patients with peripheral vascular disease: dietitian or diet fact sheet? , 1989, The Medical journal of Australia.

[7]  J. Marr,et al.  Diet and heart: a postscript. , 1977, British medical journal.

[8]  K. Hutchison,et al.  Effects of two "lipid-lowering" diets on plasma lipid levels of patients with peripheral vascular disease. , 1984, Journal of the American Dietetic Association.

[9]  Ivar Heuch,et al.  Fish consumption and mortality from coronary heart disease. , 1985, The New England journal of medicine.

[10]  R. Prescott,et al.  Edinburgh Artery Study: prevalence of asymptomatic and symptomatic peripheral arterial disease in the general population. , 1991, International journal of epidemiology.

[11]  W. Kannel,et al.  Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. , 2020, Annals of internal medicine.

[12]  D. Wood,et al.  Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene , 1991, The Lancet.

[13]  K. Katsouyanni,et al.  Diet and peripheral arterial occlusive disease: the role of poly-, mono-, and saturated fatty acids. , 1991, American journal of epidemiology.

[14]  G. Block,et al.  Use of vitamin and mineral supplements: demographics and amounts of nutrients consumed. The 1987 Health Interview Survey. , 1990, American journal of epidemiology.

[15]  F E Preston,et al.  Beneficial effect of fish oil on blood viscosity in peripheral vascular disease. , 1984, British medical journal.

[16]  K. Hutchison,et al.  Effects of dietary manipulation on vascular status of patients with peripheral vascular disease. , 1983, JAMA.

[17]  S. Renaud,et al.  Wine, alcohol, platelets, and the French paradox for coronary heart disease , 1992, The Lancet.

[18]  J. Yarnell,et al.  A short dietary questionnaire for use in an epidemiological survey: comparison with weighed dietary records. , 1983, Human nutrition. Applied nutrition.