The caveolin proteins

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[2]  Steve McClain,et al.  Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. , 2003, The American journal of pathology.

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[4]  Richard G. W. Anderson,et al.  Multiple Functions of Caveolin-1* , 2002, The Journal of Biological Chemistry.

[5]  David S. Park,et al.  Caveolin-3 Knock-out Mice Develop a Progressive Cardiomyopathy and Show Hyperactivation of the p42/44 MAPK Cascade* , 2002, The Journal of Biological Chemistry.

[6]  David S. Park,et al.  Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. , 2002, The American journal of pathology.

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[10]  Lucas Pelkmans,et al.  Endocytosis Via Caveolae , 2002, Traffic.

[11]  G. Christ,et al.  Caveolin-2-Deficient Mice Show Evidence of Severe Pulmonary Dysfunction without Disruption of Caveolae , 2002, Molecular and Cellular Biology.

[12]  David S. Park,et al.  Caveolin-1-deficient Mice Are Lean, Resistant to Diet-induced Obesity, and Show Hypertriglyceridemia with Adipocyte Abnormalities* , 2002, The Journal of Biological Chemistry.

[13]  M. Lisanti,et al.  Caveolin-deficient mice: insights into caveolar function human disease. , 2001, The Journal of clinical investigation.

[14]  G. Christ,et al.  Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. , 2001, The Journal of biological chemistry.

[15]  M. Lisanti,et al.  Caveolae and caveolin-3 in muscular dystrophy. , 2001, Trends in molecular medicine.

[16]  M. Lisanti,et al.  Adenovirus-mediated expression of caveolin-1 in mouse liver increases plasma high-density lipoprotein levels. , 2001, Biochemistry.

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[19]  L. Norkin.  Caveolae in the uptake and targeting of infectious agents and secreted toxins. , 2001, Advanced drug delivery reviews.

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[22]  Pingsheng Liu,et al.  Cell-specific targeting of caveolin-1 to caveolae, secretory vesicles, cytoplasm or mitochondria. , 2001, Journal of cell science.

[23]  E. Ikonen,et al.  A Caveolin Dominant Negative Mutant Associates with Lipid Bodies and Induces Intracellular Cholesterol Imbalance , 2001, The Journal of cell biology.

[24]  T Hayakawa,et al.  Invasion activating caveolin-1 mutation in human scirrhous breast cancers. , 2001, Cancer research.

[25]  M. Bitzer,et al.  Caveolin-1 Regulates Transforming Growth Factor (TGF)-β/SMAD Signaling through an Interaction with the TGF-β Type I Receptor* , 2001, The Journal of Biological Chemistry.

[26]  M. Lisanti,et al.  Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway. , 2000, The Journal of biological chemistry.

[27]  S. Yokoyama,et al.  Involvement of caveolin-1 in cholesterol enrichment of high density lipoprotein during its assembly by apolipoprotein and THP-1 cells. , 2000, Journal of lipid research.

[28]  F. Sotgia,et al.  Caveolin-3 directly interacts with the C-terminal tail of beta -dystroglycan. Identification of a central WW-like domain within caveolin family members. , 2000, The Journal of biological chemistry.

[29]  M. Lisanti,et al.  Limb-girdle Muscular Dystrophy (LGMD-1C) Mutants of Caveolin-3 Undergo Ubiquitination and Proteasomal Degradation , 2000, The Journal of Biological Chemistry.

[30]  M. Wilson,et al.  Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette. , 2000, Molecular endocrinology.

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[32]  M. Lisanti,et al.  The Cyclin D1 Gene Is Transcriptionally Repressed by Caveolin-1* , 2000, The Journal of Biological Chemistry.

[33]  M. Lisanti,et al.  A Molecular Dissection of Caveolin-1 Membrane Attachment and Oligomerization , 2000, The Journal of Biological Chemistry.

[34]  J. Coers,et al.  Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth , 1999, Nature Cell Biology.

[35]  C. Peschle,et al.  Expression of Caveolin-1 Is Required for the Transport of Caveolin-2 to the Plasma Membrane , 1999, The Journal of Biological Chemistry.

[36]  M. Lisanti,et al.  Phenotypic Behavior of Caveolin-3 Mutations That Cause Autosomal Dominant Limb Girdle Muscular Dystrophy (LGMD-1C) , 1999, The Journal of Biological Chemistry.

[37]  J. Hancock,et al.  Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains , 1999, Nature Cell Biology.

[38]  J. Srinivasan,et al.  Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans , 1999, Nature Cell Biology.

[39]  S. Steinberg,et al.  Activated protein kinase C isoforms target to cardiomyocyte caveolae : stimulation of local protein phosphorylation. , 1999, Circulation research.

[40]  J. Engelman,et al.  Sequence and detailed organization of the human caveolin‐1 and ‐2 genes located near the D7S522 locus (7q31.1) , 1999, FEBS letters.

[41]  J. Engelman,et al.  Targeted downregulation of caveolin‐1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade , 1998, The EMBO journal.

[42]  J. Engelman,et al.  Genes encoding human caveolin‐1 and ‐2 are co‐localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers , 1998, FEBS letters.

[43]  J. Engelman,et al.  Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo , 1998, FEBS letters.

[44]  M. McNiven,et al.  Dynamin-mediated Internalization of Caveolae , 1998, The Journal of cell biology.

[45]  P. Oh,et al.  Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium , 1998, The Journal of cell biology.

[46]  F. Zara,et al.  Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy , 1998, Nature Genetics.

[47]  Jan E Schnitzer,et al.  Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells , 1998, Oncogene.

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[49]  M. Lisanti,et al.  Interaction of a Receptor Tyrosine Kinase, EGF-R, with Caveolins , 1997, The Journal of Biological Chemistry.

[50]  E. V. van Donselaar,et al.  Cell-type and Tissue-specific Expression of Caveolin-2 , 1997, The Journal of Biological Chemistry.

[51]  R. Parton,et al.  Regulation of caveolin and caveolae by cholesterol in MDCK cells. , 1997, Journal of lipid research.

[52]  A. Bist,et al.  Two sterol regulatory element-like sequences mediate up-regulation of caveolin gene transcription in response to low density lipoprotein free cholesterol. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Charles C. Wykoff,et al.  Recombinant Expression of Caveolin-1 in Oncogenically Transformed Cells Abrogates Anchorage-independent Growth* , 1997, The Journal of Biological Chemistry.

[54]  Richard G. W. Anderson,et al.  Murine SR-BI, a High Density Lipoprotein Receptor That Mediates Selective Lipid Uptake, Is N-Glycosylated and Fatty Acylated and Colocalizes with Plasma Membrane Caveolae* , 1997, The Journal of Biological Chemistry.

[55]  P. Oh,et al.  Organized Endothelial Cell Surface Signal Transduction in Caveolae Distinct from Glycosylphosphatidylinositol-anchored Protein Microdomains* , 1997, The Journal of Biological Chemistry.

[56]  Tsuneya Ikezu,et al.  Identification of Peptide and Protein Ligands for the Caveolin-scaffolding Domain , 1997, The Journal of Biological Chemistry.

[57]  T. Katada,et al.  Identification, Sequence, and Expression of an Invertebrate Caveolin Gene Family from the Nematode Caenorhabditis elegans , 1997, The Journal of Biological Chemistry.

[58]  R. Parton,et al.  Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation , 1997, The Journal of cell biology.

[59]  Richard G. W. Anderson,et al.  A Role for Caveolin in Transport of Cholesterol from Endoplasmic Reticulum to Plasma Membrane* , 1996, The Journal of Biological Chemistry.

[60]  M. Lisanti,et al.  Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases. , 1996, The Journal of biological chemistry.

[61]  M. Lisanti,et al.  Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells , 1996, The Journal of Biological Chemistry.

[62]  M. Lisanti,et al.  Phosphorylation of Caveolin by Src Tyrosine Kinases , 1996, The Journal of Biological Chemistry.

[63]  H. Lodish,et al.  Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle (*) , 1996, The Journal of Biological Chemistry.

[64]  H. Lodish,et al.  Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[65]  M. Lisanti,et al.  Expression and Characterization of Recombinant Caveolin , 1996, The Journal of Biological Chemistry.

[66]  R. Parton,et al.  M‐caveolin, a muscle‐specific caveolin‐related protein , 1995, FEBS letters.

[67]  C. Fielding,et al.  Plasma membrane caveolae mediate the efflux of cellular free cholesterol. , 1995, Biochemistry.

[68]  F. Wieland,et al.  VIP21/caveolin is a cholesterol-binding protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[69]  M. Lisanti,et al.  Oligomeric structure of caveolin: implications for caveolae membrane organization. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[70]  H. Lodish,et al.  Caveolin Isoforms Differ in Their N-terminal Protein Sequence and Subcellular Distribution. IDENTIFICATION AND EPITOPE MAPPING OF AN ISOFORM-SPECIFIC MONOCLONAL ANTIBODY PROBE (*) , 1995, The Journal of Biological Chemistry.

[71]  F. Vogel,et al.  VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro. , 1995, Molecular biology of the cell.

[72]  P. Oh,et al.  Endothelial Caveolae Have the Molecular Transport Machinery for Vesicle Budding, Docking, and Fusion Including VAMP, NSF, SNAP, Annexins, and GTPases (*) , 1995, The Journal of Biological Chemistry.

[73]  D. Dietzen,et al.  Caveolin Is Palmitoylated on Multiple Cysteine Residues , 1995, The Journal of Biological Chemistry.

[74]  D. Baltimore,et al.  Reduction of caveolin and caveolae in oncogenically transformed cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

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[77]  R. F. Cook,et al.  Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease , 1994, The Journal of cell biology.

[78]  M. Lisanti,et al.  Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells , 1993, The Journal of cell biology.

[79]  D. Soppet,et al.  Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[80]  P. Dupree,et al.  VIP21, a 21-kD membrane protein is an integral component of trans-Golgi- network-derived transport vesicles , 1992, The Journal of cell biology.

[81]  Richard G. W. Anderson,et al.  Caveolin, a protein component of caveolae membrane coats , 1992, Cell.

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[83]  J. Glenney,et al.  Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton , 1989, The Journal of cell biology.

[84]  L. Orci,et al.  Non-coated membrane invaginations are involved in binding and internalization of cholera and tetanus toxins , 1982, Nature.

[85]  F. Sotgia,et al.  Impairment of caveolae formation and T-system disorganization in human muscular dystrophy with caveolin-3 deficiency. , 2002, The American journal of pathology.

[86]  Richard G. W. Anderson,et al.  Alterations in membrane cholesterol that affect structure and function of caveolae. , 2002, Methods in enzymology.

[87]  M. Lisanti,et al.  Limb-girdle Muscular Dystrophy (LGMD-1C) Mutants of Caveolin-3 Undergo Ubiquitination and Proteasomal Degradation TREATMENT WITH PROTEASOMAL INHIBITORS BLOCKS THE DOMINANT NEGATIVE EFFECT OF LGMD-1C MUTANTS AND RESCUES WILD-TYPE CAVEOLIN-3* , 2000 .

[88]  M. Lisanti,et al.  Purification of caveolae-derived membrane microdomains containing lipid-anchored signaling molecules, such as GPI-anchored proteins, H-Ras, Src-family tyrosine kinases, eNOS, and G-protein alpha-, beta-, and gamma-subunits. , 1999, Methods in molecular biology.

[89]  D. Brown,et al.  Functions of lipid rafts in biological membranes. , 1998, Annual review of cell and developmental biology.

[90]  M. Lisanti,et al.  Phosphorylation of Caveolin by Src Tyrosine Kinases THE a-ISOFORM OF CAVEOLIN IS SELECTIVELY PHOSPHORYLATED BY v-Src IN VIVO* , 1996 .

[91]  M. Lisanti,et al.  Caveolae purification and glycosylphosphatidylinositol-linked protein sorting in polarized epithelia. , 1995, Methods in enzymology.

[92]  M. Lisanti,et al.  Expression and Characterization of Recombinant Caveolin PURIFICATION BY POLYHISTIDINE TAGGING AND CHOLESTEROL-DEPENDENT INCORPORATION INTO DEFINED LIPID MEMBRANES* , 1995 .

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