Orexin-stimulated MAP kinase cascades are activated through multiple G-protein signalling pathways in human H295R adrenocortical cells: diverse roles for orexins A and B.
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H. Randeva | H. Lehnert | J. Chen | P. Stanfield | O. Jöhren | A. Conner | M. Ramanjaneya | J. Brown | Prashantha Kumar | James E. P. Brown
[1] C. Tortorella,et al. Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade , 1999, The Journal of Steroid Biochemistry and Molecular Biology.
[2] A. Bonci,et al. Orexin B/hypocretin 2 increases glutamatergic transmission to ventral tegmental area neurons , 2008, The European journal of neuroscience.
[3] K. Eidne,et al. Orexin receptors: Distinct β-arrestin and internalization profiles for subtypes 1 and 2 , 2006, Frontiers in Neuroendocrinology.
[4] M. Kathmann,et al. Presynaptic neuropeptide receptors. , 2008, Handbook of experimental pharmacology.
[5] B. H. Shah,et al. Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation. , 2002, Molecular pharmacology.
[6] H. Wootz,et al. G-protein-coupled OX1 Orexin/hcrtr-1 Hypocretin Receptors Induce Caspase-dependent and -independent Cell Death through p38 Mitogen-/Stress-activated Protein Kinase* , 2006, Journal of Biological Chemistry.
[7] R. Tapping,et al. BMK1 Mediates Growth Factor-induced Cell Proliferation through Direct Cellular Activation of Serum and Glucocorticoid-inducible Kinase* , 2001, The Journal of Biological Chemistry.
[8] R. Philp,et al. PKC δ phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2 , 2007 .
[9] C. Der,et al. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer , 2007, Oncogene.
[10] G. Nussdorfer,et al. Preproorexin and orexin receptors are expressed in cortisol-secreting adrenocortical adenomas, and orexins stimulate in vitro cortisol secretion and growth of tumor cells. , 2005, The Journal of clinical endocrinology and metabolism.
[11] S. Carr,et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. , 1998, Cell.
[12] H. Haas,et al. OX1 orexin receptors activate extracellular signal-regulated kinase in Chinese hamster ovary cells via multiple mechanisms: the role of Ca2+ influx in OX1 receptor signaling. , 2006, Molecular endocrinology.
[13] J. Flier,et al. Obesity and the Hypothalamus: Novel Peptides for New Pathways , 1998, Cell.
[14] A. Ziółkowska,et al. Orexins modulate the growth of cultured rat adrenocortical cells, acting through type 1 and type 2 receptors coupled to the MAPK p42/p44- and p38-dependent cascades. , 2005, International journal of molecular medicine.
[15] H. Randeva,et al. The signalling profile of recombinant human orexin-2 receptor. , 2008, Cellular signalling.
[16] Marc Parmentier,et al. Distinct Recognition of OX1 and OX2Receptors by Orexin Peptides , 2003, Journal of Pharmacology and Experimental Therapeutics.
[17] O. Jöhren,et al. Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats. , 2001, Endocrinology.
[18] O. Jöhren,et al. Adrenal expression of orexin receptor subtypes is differentially regulated in experimental streptozotocin induced type-1 diabetes , 2006, Peptides.
[19] H. Randeva,et al. Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: implications for adrenal function and energy homeostasis. , 2001, The Journal of clinical endocrinology and metabolism.
[20] I. Bird,et al. The NCI-H295 cell line: a pluripotent model for human adrenocortical studies , 1994, Molecular and Cellular Endocrinology.
[21] Rachel S White,et al. Orexin A Induces GnRH Gene Expression and Secretion from GT1-7 Hypothalamic GnRH Neurons , 2007, Neuroendocrinology.
[22] D Smart,et al. SB‐334867‐A: the first selective orexin‐1 receptor antagonist , 2001, British journal of pharmacology.
[23] C. Tortorella,et al. Orexins stimulate glucocorticoid secretion from cultured rat and human adrenocortical cells, exclusively acting via the OX1 receptor , 2005, The Journal of Steroid Biochemistry and Molecular Biology.
[24] S. Carr,et al. Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior , 1998, Cell.
[25] William A. Catterall,et al. Ins and outs , 1994, Nature.
[26] H. Randeva,et al. Expression and coupling characteristics of the CRH and orexin type 2 receptors in human fetal adrenals. , 2001, The Journal of clinical endocrinology and metabolism.
[27] A Stricker-Krongrad,et al. Independent feeding and metabolic actions of orexins in mice. , 1998, Biochemical and biophysical research communications.
[28] H. Randeva,et al. Food deprivation differentially modulates orexin receptor expression and signaling in rat hypothalamus and adrenal cortex. , 2005, American journal of physiology. Endocrinology and metabolism.
[29] T. Gorojankina,et al. Study of orexins signal transduction pathways in rat olfactory mucosa and in olfactory sensory neurons-derived cell line Odora: Multiple orexin signalling pathways , 2007, Regulatory Peptides.
[30] M. Otis,et al. Role of MAPKs in angiotensin II-induced steroidogenesis in rat glomerulosa cells , 2007, Molecular and Cellular Endocrinology.
[31] R. Philp,et al. PKC delta phosphorylates p52ShcA at Ser29 to regulate ERK activation in response to H2O2. , 2007, Cellular signalling.
[32] E. Hull,et al. A Role for Hypocretin (Orexin) in Male Sexual Behavior , 2007, The Journal of Neuroscience.
[33] H. Randeva,et al. Orexin receptors and G-protein coupling: evidence for another "promiscuous" seven transmembrane domain receptor. , 2003, Journal of pharmacological sciences.
[34] P. Sexton,et al. ‘Ins and outs’ of seven-transmembrane receptor signalling to ERK , 2005, Trends in Endocrinology & Metabolism.
[35] T. Voisin,et al. Orexin-induced apoptosis: the key role of the seven-transmembrane domain orexin type 2 receptor. , 2006, Endocrinology.
[36] G. Mazzocchi,et al. Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins A and B. , 2001, The Journal of clinical endocrinology and metabolism.
[37] J. Kukkonen,et al. OX1 Orexin Receptors Couple to Adenylyl Cyclase Regulation via Multiple Mechanisms* , 2005, Journal of Biological Chemistry.
[38] G. Mazzocchi,et al. Orexin A stimulates cortisol secretion from human adrenocortical cells through activation of the adenylate cyclase-dependent signaling cascade. , 2001, The Journal of clinical endocrinology and metabolism.
[39] G. Nussdorfer,et al. Effects of orexins A and B on the secretory and proliferative activity of immature and regenerating rat adrenal glands. , 2001, Histology and histopathology.
[40] H. Randeva,et al. Orexins stimulate steroidogenic acute regulatory (StAR) protein expression through multiple signalling pathways , 2008 .