Anorectal manometry in children with defecation disorders BSPGHAN Motility Working Group consensus statement

Defecatory disorders in children, including chronic constipation (CC) and fecal incontinence (FI), are common conditions worldwide and have a significant impact on children, their families, and the healthcare system. Anorectal manometry (ARM) and high‐resolution anorectal manometry (HRAM) are relatively novel tools for the assessment of anal sphincter function and rectal sensation and have contributed significantly to improving the understanding of the anorectum as a functional unit. ARM has been recognized as the investigation of choice for adults with symptoms of defecation disorders, including fecal incontinence (FI), evacuation difficulties, and constipation. Although it is the gold standard tool in adults, it has yet to be formally accepted as a standardized diagnostic tool in the pediatric age, with limited knowledge regarding indications, protocol, and normal values. ARM/HRAM is slowly becoming recognized among pediatricians, but given that there are currently no agreed guidelines there is a risk that will lead to diversity in practice. The British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN)—Motility Working Group (MWG) therefore has taken the opportunity to provide guidance on the use of ARM/HRAM in children with CC and/or FI.

[1]  L. Mahajan,et al.  Effects of a Psychological Preparation Intervention on Anxiety Associated with Pediatric Anorectal Manometry , 2019, International journal of pediatrics.

[2]  C. Di Lorenzo,et al.  Prevalence of Functional Defecation Disorders in Children: A Systematic Review and Meta‐Analysis , 2018, The Journal of pediatrics.

[3]  B. Chumpitazi,et al.  Physical Therapy for Fecal Incontinence in Children with Pelvic Floor Dyssynergia , 2017, The Journal of pediatrics.

[4]  L. Mahajan,et al.  Anxiety Associated With High-resolution Anorectal Manometry in Pediatric Patients and Parents , 2017, Journal of pediatric gastroenterology and nutrition.

[5]  Jia‐Feng Wu,et al.  Diagnostic Role of Anal Sphincter Relaxation Integral in High‐Resolution Anorectal Manometry for Hirschsprung Disease in Infants , 2017, The Journal of pediatrics.

[6]  M. Fox,et al.  Methods of anorectal manometry vary widely in clinical practice: Results from an international survey , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[7]  Yuan-Pang Wang,et al.  Epidemiology of functional gastrointestinal disorders in children and adolescents: A systematic review , 2017, World journal of gastroenterology.

[8]  M. Sood,et al.  An ANMS‐NASPGHAN consensus document on anorectal and colonic manometry in children , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[9]  M. Dądalski,et al.  Evaluation of the effectiveness of biofeedback therapy for functional constipation in children. , 2016, The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.

[10]  M. Benninga,et al.  Childhood constipation as an emerging public health problem. , 2016, World journal of gastroenterology.

[11]  A. Banaszkiewicz,et al.  Values From Three-dimensional High-resolution Anorectal Manometry Analysis of Children Without Lower Gastrointestinal Symptoms. , 2016, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[12]  T. Patcharatrakul,et al.  Diagnosis and Treatment of Dyssynergic Defecation , 2016, Journal of neurogastroenterology and motility.

[13]  Xianqing Jin,et al.  Evaluation of postoperative anal functions using endoanal ultrasonography and anorectal manometry in children with congenital anorectal malformations. , 2016, Journal of pediatric surgery.

[14]  A. Bharucha,et al.  How to Perform and Interpret a High-resolution Anorectal Manometry Test , 2015, Journal of neurogastroenterology and motility.

[15]  P. Dinning,et al.  The use of colonic and anorectal high‐resolution manometry and its place in clinical work and in research , 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[16]  J. Remes-Troche,et al.  Accuracy and Reproducibility of High-definition Anorectal Manometry and Pressure Topography Analyses in Healthy Subjects. , 2015, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[17]  A. Lembo,et al.  Emergency Department Burden of Constipation in the United States from 2006 to 2011 , 2015, The American Journal of Gastroenterology.

[18]  D. Kufeji,et al.  Anorectal manometry with and without ketamine for evaluation of defecation disorders in children. , 2015, Journal of pediatric surgery.

[19]  C. Gyawali,et al.  High‐resolution anorectal manometry in newborns: normative values and diagnostic utility in Hirschsprung disease , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[20]  C. Knowles,et al.  Normal values for high‐resolution anorectal manometry: a time for consensus and collaboration , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[21]  S. Scott,et al.  Traditional measures of normal anal sphincter function using high‐resolution anorectal manometry (HRAM) in 115 healthy volunteers , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[22]  Khoa Tran,et al.  Effect of Propofol on Anal Sphincter Pressure During Anorectal Manometry , 2014, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

[23]  Jeana Hong Clinical Applications of Gastrointestinal Manometry in Children , 2014, Pediatric gastroenterology, hepatology & nutrition.

[24]  A. Staiano,et al.  Evaluation and Treatment of Functional Constipation in Infants and Children: Evidence-Based Recommendations From ESPGHAN and NASPGHAN , 2014, Journal of pediatric gastroenterology and nutrition.

[25]  S. Nurko,et al.  Longitudinal and Radial Characteristics of Intra-Anal Pressures in Children Using 3D High-Definition Anorectal Manometry: New Observations , 2013, The American Journal of Gastroenterology.

[26]  Lijun Sun,et al.  Impact of Functional Constipation on Health-Related Quality of Life in Preschool Children and Their Families in Xi’an, China , 2013, PloS one.

[27]  Yuwei Li,et al.  Normal values and pressure morphology for three-dimensional high-resolution anorectal manometry of asymptomatic adults: a study in 110 subjects , 2013, International Journal of Colorectal Disease.

[28]  G. Clayden,et al.  Pathophysiology of chronic childhood constipation: functional and morphological evaluation by anorectal manometry and endosonography and colonic transit study. , 2013, Journal of pediatric surgery.

[29]  A. Zinsmeister,et al.  Phenotypic identification and classification of functional defecatory disorders using high-resolution anorectal manometry. , 2013, Gastroenterology.

[30]  M. Benninga,et al.  Review article: faecal incontinence in children: epidemiology, pathophysiology, clinical evaluation and management , 2013, Alimentary pharmacology & therapeutics.

[31]  B. Kuo,et al.  Balloon Expulsion Test as a Screen for Outlet Obstruction in Children With Chronic Constipation , 2013, Journal of pediatric gastroenterology and nutrition.

[32]  A. Zinsmeister,et al.  Normal Values for High-Resolution Anorectal Manometry in Healthy Women: Effects of Age and Significance of Rectoanal Gradient , 2012, The American Journal of Gastroenterology.

[33]  M. Fox,et al.  Chicago classification criteria of esophageal motility disorders defined in high resolution esophageal pressure topography 1 , 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[34]  R. Rosen,et al.  Anorectal Manometry May Identify Children With Spinal Cord Lesions , 2011, Journal of pediatric gastroenterology and nutrition.

[35]  B. Chumpitazi,et al.  Defecation Disorders in Children After Surgery for Hirschsprung Disease , 2011, Journal of pediatric gastroenterology and nutrition.

[36]  A. Wald,et al.  Quality of life in children and adults with constipation. , 2011, Best practice & research. Clinical gastroenterology.

[37]  S. Rajindrajith,et al.  Constipation in Children: Novel Insight Into Epidemiology, Pathophysiology and Management , 2011, Journal of neurogastroenterology and motility.

[38]  R. Kennedy,et al.  Nonpharmacologic Techniques for Distress Reduction During Emergency Medical Care: A Review , 2010 .

[39]  M. Benninga,et al.  Constipation-associated and Nonretentive Fecal Incontinence in Children and Adolescents: An Epidemiological Survey in Sri Lanka , 2010, Journal of pediatric gastroenterology and nutrition.

[40]  C. Pehl,et al.  Influence of Gender and Age on Anorectal Function: Normal Values from Anorectal Manometry in a Large Caucasian Population , 2010, Digestion.

[41]  Sunil Kumar,et al.  Manometric tests of anorectal function in 90 healthy children: a clinical study from Kuwait. , 2009, Journal of pediatric surgery.

[42]  R. Gilmont,et al.  Bioengineered internal anal sphincter derived from isolated human internal anal sphincter smooth muscle cells. , 2009, Gastroenterology.

[43]  C. Yi,et al.  Influence of Intravenous Propofol Sedation on Anorectal Manometry in Healthy Adults , 2009, The American journal of the medical sciences.

[44]  A. Papparella,et al.  Role of anorectal manometry in children with severe constipation , 2009, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[45]  G. Clayden,et al.  Evaluation of outcome of anorectal anomaly in childhood: the role of anorectal manometry and endosonography , 2008, Pediatric Surgery International.

[46]  C. Yi,et al.  Anorectal manometry in patients with chronic constipation: a single-center experience. , 2008, Hepato-gastroenterology.

[47]  M. Benninga,et al.  Epidemiology of Childhood Constipation: A Systematic Review , 2006, The American Journal of Gastroenterology.

[48]  J. Reitsma,et al.  Diagnostic Tests in Hirschsprung Disease: A Systematic Review , 2006, Journal of pediatric gastroenterology and nutrition.

[49]  J. Rosh,et al.  Chronic Childhood Constipation Is Associated with Impaired Quality of Life: A Case-Controlled Study , 2005, Journal of pediatric gastroenterology and nutrition.

[50]  J. Reitsma,et al.  Diagnosis of Hirschsprung's disease: a prospective, comparative accuracy study of common tests. , 2005, The Journal of pediatrics.

[51]  M. Post,et al.  High prevalence of incontinence among young adults with spina bifida: description, prediction and problem perception , 2005, Spinal Cord.

[52]  M. Benninga,et al.  Use of Rome II criteria in childhood defecation disorders: applicability in clinical and research practice. , 2004, The Journal of pediatrics.

[53]  J. Croffie,et al.  Impact of Sedation and Anesthesia on the Rectoanal Inhibitory Reflex in Children , 2004, Journal of pediatric gastroenterology and nutrition.

[54]  C. Di Lorenzo,et al.  Internal Anal Sphincter Achalasia in Children: Clinical Characteristics and Treatment with Clostridium botulinum Toxin , 2003, Journal of pediatric gastroenterology and nutrition.

[55]  S. Nurko,et al.  Rectal Manometry in Patients With Isolated Sacral Agenesis , 2003, Journal of pediatric gastroenterology and nutrition.

[56]  G. Clayden,et al.  Investigations for incontinence and constipation after surgery for Hirschsprung's disease in children , 2003, Pediatric Surgery International.

[57]  P. Enck,et al.  Minimum standards of anorectal manometry , 2002, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[58]  C. Di Lorenzo,et al.  Manometry studies in children: minimum standards for procedures , 2002, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[59]  W. Whitehead,et al.  Anorectal functional testing: review of collective experience , 2002, American Journal of Gastroenterology.

[60]  G. Boeckxstaens,et al.  The effect of anorectal manometry on the outcome of treatment in severe childhood constipation: a randomized, controlled trial. , 2001, Pediatrics.

[61]  M. Benninga,et al.  Manometry, Profilometry, and Endosonography: Normal Physiology and Anatomy of the Anal Canal in Healthy Children , 1994, Journal of pediatric gastroenterology and nutrition.

[62]  L. Taitz,et al.  Anorectal manometry results in defecation disorders. , 1983, Archives of disease in childhood.

[63]  D. Burleigh,et al.  Neural and pharmacologic factors affecting motility of the internal anal sphincter. , 1983, Gastroenterology.

[64]  Link,et al.  UvA-DARE ( Digital Academic Repository ) Unraveling childhood constipation : Pathophysiology , diagnostics and treatment , 2014 .

[65]  T. Purtuloğlu,et al.  Importance of anorectal manometry after definitive surgery for Hirschsprung′s disease in children , 2013, African journal of paediatric surgery : AJPS.

[66]  M. Benninga,et al.  Functional nonretentive fecal incontinence in children. , 2007, Journal of pediatric gastroenterology and nutrition.