Next generation screen printed electrochemical platforms: Non-enzymatic sensing of carbohydrates using screen printed electrodes.

The first example of a copper(ii) oxide screen printed electrode is reported which is characterised with microscopy and explored towards the electrochemical sensing of glucose, maltose, sucrose and fructose. It is shown that the non-enzymatic electrochemical sensing of glucose with cyclic voltammetry and amperometry is possible with low micro-molar up to milli-molar glucose readily detectable which compares competitively with nano-catalyst modified electrodes. The sensing of glucose shows a modest selectivity over maltose and sucrose while fructose is not detectable. An additional benefit of this approach is that metal oxides with known oxidation states can be incorporated into the screen printed electrodes allowing one to identify exactly the origin of the observed electro-catalytic response which is difficult when utilising metal oxide modified electrodes formed via electro-deposition techniques which result in a mixture of metal oxides/oxidation states. These next generation screen printed electrochemical sensing platforms provide a simplification over previous copper oxide systems offering a novel fabrication route for the mass production of electro-catalytic sensors for analytical and forensic applications.

[1]  Craig E. Banks,et al.  Characterisation of commercially available electrochemical sensing platforms , 2009 .

[2]  Shusheng Zhang,et al.  One-step synthesis of silver nanoparticles/carbon nanotubes/chitosan film and its application in glucose biosensor , 2009 .

[3]  C. Lokhande,et al.  Electrodeposited porous and amorphous copper oxide film for application in supercapacitor , 2009 .

[4]  Jianbin Zheng,et al.  Amine-terminated ionic liquid functionalized carbon nanotube-gold nanoparticles for investigating the direct electron transfer of glucose oxidase , 2009 .

[5]  E. Farjami,et al.  Fabrication of a glucose sensor based on a novel nanocomposite electrode. , 2009, Biosensors & bioelectronics.

[6]  Ali Al-Hajry,et al.  Enzymatic glucose biosensor based on flower-shaped copper oxide nanostructures composed of thin nanosheets , 2009 .

[7]  M. Jafarian,et al.  A study of the electrocatalytic oxidation of cyclohexanol on copper electrode , 2008 .

[8]  Richard G. Compton,et al.  The use of copper(II) oxide nanorod bundles for the non-enzymatic voltammetric sensing of carbohydrates and hydrogen peroxide , 2008 .

[9]  I. Taniguchi,et al.  Electrocatalytic glucose oxidation at bimetallic gold-copper nanoparticle-modified carbon electrodes in alkaline solution , 2008 .

[10]  Shuyan Gao,et al.  Green Fabrication of Hierarchical CuO Hollow Micro/Nanostructures and Enhanced Performance as Electrode Materials for Lithium-ion Batteries , 2008 .

[11]  Yu Lei,et al.  CuO Nanospheres Based Nonenzymatic Glucose Sensor , 2008 .

[12]  Rashid O. Kadara,et al.  Manufacturing electrochemical platforms: Direct-write dispensing versus screen printing , 2008 .

[13]  Adam Heller,et al.  Electrochemical glucose sensors and their applications in diabetes management. , 2008, Chemical reviews.

[14]  C. M. Li,et al.  Tailoring Zinc Oxide Nanowires for High Performance Amperometric Glucose Sensor , 2007 .

[15]  Qin Xu,et al.  Preparation of functionalized copper nanoparticles and fabrication of a glucose sensor , 2006 .

[16]  G. Rivas,et al.  Glucose biosensors based on the immobilization of copper oxide and glucose oxidase within a carbon paste matrix. , 2005, Talanta.

[17]  John H. T. Luong,et al.  Electrochemical detection of carbohydrates using copper nanoparticles and carbon nanotubes , 2004 .

[18]  Jun-Jie Zhu,et al.  Nano-Sized Copper Oxide Modified Carbon Paste Electrodes as an Amperometric Sensor for Amikacin , 2003 .

[19]  J. Zen,et al.  Photoelectrochemical oxygen sensor using copper-plated screen-printed carbon electrodes. , 2002, Analytical chemistry.

[20]  J. Zen,et al.  Electrochemical investigation of glucose sensor fabricated at copper-plated screen-printed carbon electrodes , 2002 .

[21]  G. Nagy,et al.  Copper electrode based amperometric detector cell for sugar and organic acid measurements , 2001 .

[22]  L. Gorton,et al.  Electrochemical oxidation of mono- and disaccharides at fresh as well as oxidized copper electrodes in alkaline media , 1999 .

[23]  H. Ju,et al.  (Os(bpy)2(PVI)10Cl)Cl polymer-modified carbon fiber electrodes for the electrocatalytic oxidation of NADH , 1997 .

[24]  W. LaCourse,et al.  Characterization of tobacco products by high-performance anion exchange chromatography-pulsed amperometric detection , 1996 .

[25]  Kenji,et al.  Electrocatalytic Oxidation of Carbohydrates at Copper(II)-Modified Electrodes and its Application to Flow-Through Detection. , 1994 .

[26]  William R. LaCourse,et al.  Detection of carbohydrates by capillary electrophoresis with pulsed amperometric detection , 1993 .

[27]  C. O. Huber,et al.  Electrocatalysis and amperometric detection using an electrode made of copper oxide and carbon paste , 1991 .

[28]  C. Banks,et al.  Copper Oxide – Graphite Composite Electrodes: Application to Nitrite Sensing , 2007 .

[29]  J. Zen,et al.  Flow injection analysis of hydrogen peroxide on copper-plated screen-printed carbon electrodes , 2000 .

[30]  M. Tanticharoen,et al.  Measurement of sulfite at oxide-coated copper electrodes. , 1998, The Analyst.

[31]  R. Baldwin,et al.  Comparison of metallic electrodes for constant-potential amperometric detection of carbohydrates, amino acids and related compounds in flow systems , 1991 .