Effect of Nigella sativa oil on postoperative peritoneal adhesion formation

We aim to evaluate the effect of Nigella sativa oil (NSO) on postoperative peritoneal adhesion formation in female rats. This experimental study is the first on the prevention of postoperative adhesion formation by NSO.

[1]  Aamir Ahmad,et al.  From here to eternity - the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. , 2008, Cancer therapy.

[2]  S. T. du Montcel,et al.  Adhesive Postoperative Small Bowel Obstruction: Incidence and Risk Factors of Recurrence After Surgical Treatment: A Multicenter Prospective Study , 2006, Annals of surgery.

[3]  M. Salem.  Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. , 2005, International immunopharmacology.

[4]  J. Folkman,et al.  Prevention of Intra-abdominal Adhesions Using the Antiangiogenic COX-2 Inhibitor Celecoxib , 2005, Annals of surgery.

[5]  F. de la Portilla,et al.  Prevention of Peritoneal Adhesions by Intraperitoneal Administration of Vitamin E: An Experimental Study in Rats , 2004, Diseases of the colon and rectum.

[6]  J. Boyd,et al.  Adhesion-related readmissions following gynaecological laparoscopy or laparotomy in Scotland: an epidemiological study of 24 046 patients. , 2004, Human reproduction.

[7]  G. Saed,et al.  Molecular characterization of postoperative adhesions: the adhesion phenotype. , 2004, The Journal of the American Association of Gynecologic Laparoscopists.

[8]  M. Aldemir,et al.  The Preventive Effect of Rofecoxib in Postoperative Intraperitoneal Adhesions , 2004, Acta chirurgica Belgica.

[9]  M. Başbuğ,et al.  Effect of melatonin in the prevention of post-operative adhesion formation in a rat uterine horn adhesion model. , 2003, Human reproduction.

[10]  B. Ali,et al.  Pharmacological and toxicological properties of Nigella sativa , 2003, Phytotherapy research : PTR.

[11]  T. Midtvedt,et al.  Orally delivered antibiotics which lower bacterial numbers decrease experimental intra-abdominal adhesions , 2003, Langenbeck's Archives of Surgery.

[12]  O. Badary,et al.  Thymoquinone Is a Potent Superoxide Anion Scavenger , 2003, Drug and chemical toxicology.

[13]  M. Diamond,et al.  Are pelvic adhesions preventable? , 2003, Surgical technology international.

[14]  Ji-yun Zhang,et al.  Tropical application of halcinonide cream reduces the severity and incidence of intraperitoneal adhesions in a rat model. , 2002, American journal of surgery.

[15]  A. Çeti̇n,et al.  Prevention of postoperative adhesion formation in rat uterine horn model by nimesulide: a selective COX-2 inhibitor. , 2001, Human reproduction.

[16]  P. Campbell,et al.  Evaluation of the SprayGel adhesion barrier in the rat cecum abrasion and rabbit uterine horn adhesion models. , 2001, Fertility and sterility.

[17]  M. Salem,et al.  Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. , 2000, International journal of immunopharmacology.

[18]  T. Kooistra,et al.  Use of fibrinolytic agents in the prevention of postoperative adhesion formation. , 2000, Fertility and sterility.

[19]  R. Hawthorn,et al.  The impact of adhesions on hospital readmissions over ten years after 8849 open gynaecological operations: an assessment from the Surgical and Clinical Adhesions Research Study , 2000, BJOG : an international journal of obstetrics and gynaecology.

[20]  C. V. van Blitterswijk,et al.  Effects of five different barrier materials on postsurgical adhesion formation in the rat. , 2000, Human reproduction.

[21]  İ. Koçak,et al.  Effects of Seprafilm (sodium hyaluranate-based bioresorbable), Sepracoat (0.4% hyaluronic acid), and Ringer's lactate on the prevention of postsurgical adhesion formation in rat models. , 2000, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.

[22]  M. Parker,et al.  Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study , 1999, The Lancet.

[23]  G D Hooker,et al.  Prevention of adhesion formation with use of sodium hyaluronate-based bioresorbable membrane in a rat model of ventral hernia repair with polypropylene mesh--a randomized, controlled study. , 1999, Surgery.

[24]  M. A. Khan.  Chemical composition and medicinal properties of Nigella sativa Linn. , 1999, InflammoPharmacology.

[25]  S. Perry,et al.  Abdominal adhesiolysis: inpatient care and expenditures in the United States in 1994. , 1998, Journal of the American College of Surgeons.

[26]  D. Wiseman,et al.  Time-dependent effect of tolmetin sodium in a rabbit uterine adhesion model. , 1994, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[27]  M. Intaglietta,et al.  Effect of leukocyte adhesion and microvascular permeability on capillary perfusion during ischemia-reperfusion injury in hamster cheek pouch. , 1993, International journal of microcirculation, clinical and experimental.

[28]  D. Evans,et al.  Dose dependency and wound healing aspects of the use of tissue plasminogen activator in the prevention of intra-abdominal adhesions. , 1993, American journal of surgery.

[29]  D. Loisance,et al.  [Synergic effect of Dextran 70 at 32% and an antibiotic in the prevention of peritoneal adhesions. Experimental study in rats]. , 1992, Journal de chirurgie.

[30]  M. Hatem,et al.  Studies on the antimicrobial activity of Nigella sativa seed (black cumin). , 1991, Journal of ethnopharmacology.

[31]  I. Bukovsky,et al.  The effect of prostaglandins and aspirin--an inhibitor of prostaglandin synthesis--on adhesion formation in rats. , 1991, Human reproduction.

[32]  T. Elkins,et al.  Oxygen free radicals and pelvic adhesion formation: I. Blocking oxygen free radical toxicity to prevent adhesion formation in an endometriosis model. , 1991, International journal of fertility.

[33]  K. Rodgers,et al.  Inhibition of postsurgical adhesions by liposomes containing nonsteroidal antiinflammatory drugs. , 1990, International journal of fertility.

[34]  R. Ahokas,et al.  Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat. I. , 1984, Fertility and sterility.

[35]  J. Stangel,et al.  Formation and prevention of postoperative abdominal adhesions. , 1984, The Journal of reproductive medicine.

[36]  D. Milligan,et al.  Observations on the pathogenesis of peritoneal adhesions: a light and electron microscopical study , 1974, The British journal of surgery.