Inhibition of human TNF alpha and LT in cell-free extracts and in cell culture by antisense oligonucleotides.

[1]  A. Thomson.  The cytokine handbook , 1994 .

[2]  P. McLaughlin.  Tumour necrosis factor (TNF) and inflammation , 1992 .

[3]  J. Browning,et al.  Studies on the differing effects of tumor necrosis factor and lymphotoxin on the growth of several human tumor lines. , 1989, Journal of immunology.

[4]  F. Szoka,et al.  Single-stranded phosphodiester and phosphorothioate oligonucleotides bind actinomycin D and interfere with tumor necrosis factor-induced lysis in the L929 cytotoxicity assay. , 1993, Antisense research and development.

[5]  S. Reichard.  Progress in leukocyte biology , 1985 .

[6]  D. Prockop,et al.  Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA. , 1994, Biochemistry.

[7]  N. Ruddle,et al.  The role of lymphotoxin in inflammation. , 1988, Progress in allergy.

[8]  A. Dritschilo,et al.  Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides. , 1993, Biochemical and biophysical research communications.

[9]  M. Guenounou,et al.  Immunomodulation by cytokine antisense oligonucleotides. , 1995, European cytokine network.

[10]  J. Fluck,et al.  Four cell-secreted cytokines act synergistically to maintain long term proliferation of human B cell lines in vitro. , 1992, Journal of immunology.

[11]  S. Nedospasov,et al.  An autocrine growth factor constitutively produced by a human lymphoblastoid B-cell line is serologically related to lymphotoxin (TNF-beta). , 1989, Molecular immunology.

[12]  D. Ecker,et al.  Implication of RNA structure on antisense oligonucleotide hybridization kinetics. , 1992, Biochemistry.

[13]  T. Hunt,et al.  The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations. , 1986, Nucleic acids research.

[14]  J. Toulmé,et al.  Specific regulation of gene expression by antisense, sense and antigene nucleic acids. , 1990, Biochimica et biophysica acta.

[15]  J. Toulmé,et al.  Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. , 1989, Nucleic acids research.

[16]  E. Uhlmann,et al.  Antisense oligonucleotides: a new therapeutic principle , 1990 .

[17]  W. Fiers,et al.  Synthesis and maturation of recombinant human tumor necrosis factor in eukaryotic systems , 1986, FEBS letters.

[18]  M. de Ley,et al.  Inhibition of human interferon‐gamma expression by antisense oligodeoxynucleotides , 1994, Journal of leukocyte biology.

[19]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[20]  L. Old.  Tumour necrosis factor. Polypeptide mediator network. , 1987, Nature.

[21]  A. Cope,et al.  Lymphotoxin acts as an autocrine growth factor for Epstein‐Barr virus‐transformed B cells and differentiated Burkitt lymphoma cell lines , 1994, European journal of immunology.

[22]  G. Gifford,et al.  A photometric and plaque assay for macrophage mediated tumor cell cytotoxicity. , 1983, Journal of immunological methods.

[23]  P. Terranova,et al.  Molecular, biochemical, and functional characteristics of tumor necrosis factor-alpha produced by human placental cytotrophoblastic cells. , 1993, Journal of immunology.

[24]  M. Jäättelä.  Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin. , 1991, Laboratory investigation; a journal of technical methods and pathology.

[25]  C. Brosnan,et al.  Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. , 1991, The Journal of clinical investigation.

[26]  J. Toulmé,et al.  Effect of RNA secondary structure and modified bases on the inhibition of trypanosomatid protein synthesis in cell free extracts by antisense oligodeoxynucleotides. , 1990, Nucleic acids research.

[27]  M. Zuker.  Computer prediction of RNA structure. , 1989, Methods in enzymology.

[28]  J. Toulmé,et al.  An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites. , 1987, Gene.

[29]  A. Kaji,et al.  Nucleotide sequence of a cDNA encoding human tumor necrosis factor β from B lymphoblastoid cell RPMI 1788 , 1992, FEBS letters.