The comparison of ultrasonographic placenta examination with pathohistologic verification of fetal anomalies.

Ultrasonographic diagnostics is a sovereign diagnostic method of discovering disorders in growth and development of embryo. The main aim of this research was The Comparison of Ultrasonographic Placenta Examination with Pathohistologic Treatment of Placenta considering those pregnancies, which were previously verified to have embryo anomalies, and which were ended by the procedure of feticide. During the period of 2005-2008, 15 pregnant women, with gestation between 24th and 28th week, were hospitalized in our clinic. The patients with the embryo anomalies were divided into three groups: I--the group with the diagnosis of embryo hydrocephalus, II--the group with the diagnosis of other anomalies of growth of embryo's CNS, III--the group of patients with other embryo anomalies. Pathohistologic placenta examinations were carried out in the Department of Pathology and Forensic Medicine in KC Kragujevac. The ultrasonographic placenta finding of the patients with the different embryo anomalies was not statistically very different (chi2-test; p = 0.073). However, beside the lack of the significant difference, what was reasonable considering the size of the sample, we noticed quite different ultrasonographic findings of the placenta examination of the patients having the embryo with hydrocephalus in comparison to those patients having the other embryo anomalies of CNS. The ultrasonographic placenta examination of the patients having other embryo anomalies was similar to the finding of the patients having the embryo with hydrocephalus, and the most frequent finding in the group with hydrocephalus was a cystic degeneration of placenta, and in the group with other anomalies the hydrops placenta anomalies. Among the groups of patients with different placenta anomalies, statistically significant difference was not noticed in the pathohistologic finding obtained by placenta examination (chi2-test; p = 0.955). Ultrasonography is a sovereign, non-invasive diagnostic procedure in antenatal protection of pregnant women. If we should doubt that there exists an inadequate growth and development of embryo, such pregnancy must be correctly diagnosed and treated as soon as possible, ideally until 22nd week of gestation (Tab. 4, Fig. 1, Ref. 7).