Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

[1]  David Haussler,et al.  The UCSC Genome Browser database: 2014 update , 2013, Nucleic Acids Res..

[2]  E. Nice,et al.  Chemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection , 2013, Journal of Translational Medicine.

[3]  Sean R. Davis,et al.  NCBI GEO: archive for functional genomics data sets—update , 2012, Nucleic Acids Res..

[4]  O. Abdel-Wahab,et al.  The role of mutations in epigenetic regulators in myeloid malignancies , 2012, Nature Reviews Cancer.

[5]  C. Erneux,et al.  A specific increase in inositol 1,4,5-trisphosphate 3-kinase B expression upon differentiation of human embryonic stem cells. , 2012, Cellular signalling.

[6]  P. Real,et al.  SCL/TAL1 regulates hematopoietic specification from human embryonic stem cells. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[7]  Gina M. Bernardo,et al.  FOXA1: a transcription factor with parallel functions in development and cancer. , 2012, Bioscience reports.

[8]  T. Down,et al.  Genome Wide Analysis of Acute Myeloid Leukemia Reveal Leukemia Specific Methylome and Subtype Specific Hypomethylation of Repeats , 2012, PloS one.

[9]  J. Mpindi,et al.  HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation , 2012, Oncogene.

[10]  K. Döhner,et al.  A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy , 2012, Haematologica.

[11]  L. Pasqualucci,et al.  Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype. , 2011, Blood.

[12]  F. Speleman,et al.  PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies , 2011, British journal of haematology.

[13]  Michael A McDevitt,et al.  Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation , 2010, Leukemia & lymphoma.

[14]  L. van Neste,et al.  Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis , 2010, Oncogene.

[15]  G. Shurin,et al.  Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells. , 2010, Cancer research.

[16]  C. Glass,et al.  Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. , 2010, Molecular cell.

[17]  Michael Rehli,et al.  General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells. , 2010, Cancer research.

[18]  D. Berry,et al.  DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  Bob Löwenberg,et al.  Review Articles (434 articles) , 2008 .

[20]  Fabien Campagne,et al.  DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. , 2010, Cancer cell.

[21]  J. Hartman,et al.  Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation , 2009, Breast Cancer Research.

[22]  Lucy Skrabanek,et al.  MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. , 2009, Blood.

[23]  J. Byrd,et al.  Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia , 2009, Proceedings of the National Academy of Sciences.

[24]  David A. Williams,et al.  Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells. , 2009, Blood.

[25]  J. Downing,et al.  Mouse models of human AML accurately predict chemotherapy response. , 2009, Genes & development.

[26]  C. O'keefe,et al.  Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. , 2009, Blood.

[27]  C. Plass,et al.  Epigenetics in acute myeloid leukemia. , 2008, Seminars in oncology.

[28]  Ø. Bruserud,et al.  Review: genetic models of acute myeloid leukaemia , 2008, Oncogene.

[29]  Gordon K. Smyth,et al.  A comparison of background correction methods for two-colour microarrays , 2007, Bioinform..

[30]  W. Hofmann,et al.  The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia , 2007 .

[31]  M. Lübbert,et al.  Acute Myeloid Leukemia: Epidemiology and Etiology , 2006, Cancer.

[32]  C. Goparaju,et al.  Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression , 2006, Molecular Cancer.

[33]  T. Onda,et al.  Down-regulation of 1D-myo-inositol 1,4,5-trisphosphate 3-kinase A protein expression in oral squamous cell carcinoma. , 2006, International journal of oncology.

[34]  John K Field,et al.  Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[35]  S. Fujita,et al.  Novel RUNX1‐PRDM16 fusion transcripts in a patient with acute myeloid leukemia showing t(1;21)(p36;q22) , 2005, Genes, chromosomes & cancer.

[36]  J. Kutok,et al.  Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1 , 2004, Nature Genetics.

[37]  R. Tibshirani,et al.  Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. , 2004, The New England journal of medicine.

[38]  Ping Ji,et al.  Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells , 2004, Molecular and Cellular Biology.

[39]  M. Esteller.  Profiling aberrant DNA methylation in hematologic neoplasms: a view from the tip of the iceberg. , 2003, Clinical immunology.

[40]  R. Claus,et al.  Epigenetic targets in hematopoietic malignancies , 2003, Oncogene.

[41]  J. DeGregori,et al.  Defective Gene Expression, S Phase Progression, and Maturation during Hematopoiesis in E2F1/E2F2 Mutant Mice , 2003, Molecular and Cellular Biology.

[42]  Donald Metcalf,et al.  The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12 , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[43]  M. Ehrlich,et al.  DNA methylation in cancer: too much, but also too little , 2002, Oncogene.

[44]  M. Oh,et al.  Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects. , 2001, Nucleic acids research.

[45]  Christine Brun,et al.  In silico prediction of protein-protein interactions in human macrophages , 2001, BMC Research Notes.

[46]  S. Clark,et al.  Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. , 1999, Cancer research.

[47]  M. Caligiuri,et al.  Restriction landmark genome scanning for aberrant methylation in primary refractory and relapsed acute myeloid leukemia; involvement of the WIT-1 gene , 1999, Oncogene.

[48]  S. Baylin,et al.  HIC1 hypermethylation is a late event in hematopoietic neoplasms. , 1997, Cancer research.

[49]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[50]  C. Plass,et al.  Enrichment of methylated DNA by methyl-CpG immunoprecipitation. , 2013, Methods in molecular biology.

[51]  Gina M. Bernardo,et al.  FOXA 1 : a transcription factor with parallel functions in development and cancer , 2011 .

[52]  H. Tien,et al.  CEBPA methylation as a prognostic biomarker in patients with de novo acute myeloid leukemia , 2011, Leukemia.

[53]  C. Müller-Tidow,et al.  DNA methylation as a pathogenic event and as a therapeutic target in AML. , 2011, Cancer treatment reviews.

[54]  W. Hofmann,et al.  The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia. , 2007, Blood.

[55]  Achim Leutz,et al.  Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1 , 2006, Nature Genetics.

[56]  T. Onda,et al.  Down-regulation of 1 D-myo-inositol 1 , 4 , 5-trisphosphate 3-kinase A protein expression in oral squamous cell carcinoma , 2006 .

[57]  Mathematical and Computing Sciences , 2004 .