Photochemical Acceleration of DNA Strand Displacement by Using Ultrafast DNA Photo‐crosslinking

DNA strand displacement is an essential reaction in genetic recombination, biological processes, and DNA nanotechnology. In particular, various DNA nanodevices enable complicated calculations. However, it takes time before the output is obtained, so acceleration of DNA strand displacement is required for a rapid‐response DNA nanodevice. Herein, DNA strand displacement by using DNA photo‐crosslinking to accelerate this displacement is evaluated. The DNA photo‐crosslinking of 3‐cyanovinylcarbazole (CNVK) was accelerated at least 20 times, showing a faster DNA strand displacement. The rate of photo‐crosslinking is a key factor and the rate of DNA strand displacement is accelerated through ultrafast photo‐crosslinking. The rate of DNA strand displacement was regulated by photoirradiation energy.

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