Sirtuin 1 and endothelial glycocalyx

[1]  T. Rabelink,et al.  Endothelial glycocalyx hyaluronan: regulation and role in prevention of diabetic complications. , 2020, The American journal of pathology.

[2]  B. Flamion,et al.  Endothelial glycocalyx impairment in disease: Focus on hyaluronan shedding. , 2020, The American journal of pathology.

[3]  M. Goligorsky,et al.  GLYCOCALYX IN ENDOTOXEMIA AND SEPSIS. , 2020, The American journal of pathology.

[4]  Y. Cho,et al.  Tissue-resident natural killer cells exacerbate tubulointerstitial fibrosis by activating transglutaminase 2 and syndecan-4 in a model of aristolochic acid-induced nephropathy , 2019, BMB reports.

[5]  T. Jenssen,et al.  Matrix metalloproteinase‐9 mediated shedding of syndecan‐4 in glomerular endothelial cells , 2019, Microcirculation.

[6]  J. Tarbell,et al.  Endothelial surface glycocalyx (ESG) components and ultra-structure revealed by stochastic optical reconstruction microscopy (STORM). , 2019, Biorheology.

[7]  H. Dihazi,et al.  Dickkopf-3 in aberrant endothelial secretome triggers renal fibroblast activation and endothelial–mesenchymal transition , 2019, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[8]  G. Gambaro,et al.  Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury , 2018, Oncotarget.

[9]  M. Goligorsky,et al.  Endothelial cell dysfunction and glycocalyx - A vicious circle. , 2018, Matrix biology : journal of the International Society for Matrix Biology.

[10]  H. Dihazi,et al.  Fibrogenic Secretome of Sirtuin 1-Deficient Endothelial Cells: Wnt, Notch and Glycocalyx Rheostat , 2018, Front. Physiol..

[11]  H. Dihazi,et al.  Endothelial dysfunction is a superinducer of syndecan-4: fibrogenic role of its ectodomain. , 2018, American journal of physiology. Heart and circulatory physiology.

[12]  M. Goligorsky,et al.  Endothelial glycocalyx—the battleground for complications of sepsis and kidney injury , 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[13]  H. Dihazi,et al.  The third path of tubulointerstitial fibrosis: aberrant endothelial secretome. , 2017, Kidney international.

[14]  D. Liveris,et al.  Therapeutic Restoration of Endothelial Glycocalyx in Sepsis , 2017, The Journal of Pharmacology and Experimental Therapeutics.

[15]  A. Lupo,et al.  Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545 , 2017, Oncotarget.

[16]  R. Sanderson,et al.  Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy , 2017, The FEBS journal.

[17]  G. Gambaro,et al.  Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury , 2016, PloS one.

[18]  G. Christensen,et al.  Syndecans in heart fibrosis , 2016, Cell and Tissue Research.

[19]  M. Götte,et al.  Shed proteoglycans in tumor stroma , 2016, Cell and Tissue Research.

[20]  E. Pasini,et al.  Endothelial Glycocalyx: Shedding Light on Malaria Pathogenesis. , 2016, Trends in molecular medicine.

[21]  M. Goligorsky,et al.  Sirtuins, Cell Senescence, and Vascular Aging. , 2016, The Canadian journal of cardiology.

[22]  T. Rabelink,et al.  Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis. , 2016, The American journal of pathology.

[23]  T. Rabelink,et al.  Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx. , 2016, Journal of the American Society of Nephrology : JASN.

[24]  M. Goligorsky,et al.  Mechanotransduction of the endothelial glycocalyx mediates nitric oxide production through activation of TRP channels. , 2016, American journal of physiology. Cell physiology.

[25]  J. Tarbell,et al.  EXOCYTOSIS OF ENDOTHELIAL LYSOSOME‐RELATED ORGANELLES HAIR‐TRIGGERS A PATCHY LOSS OF GLYCOCALYX AT THE ONSET OF SEPSIS , 2016, The American journal of pathology.

[26]  W. Pan,et al.  Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK , 2016, PloS one.

[27]  I. Sjaastad,et al.  Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice. , 2015, Journal of molecular and cellular cardiology.

[28]  L. Guarente,et al.  The multifaceted functions of sirtuins in cancer , 2015, Nature Reviews Cancer.

[29]  M. Jacob,et al.  Degradation of the endothelial glycocalyx in clinical settings: searching for the sheddases , 2015, British journal of clinical pharmacology.

[30]  H. Vink,et al.  Perturbed mechanotransduction by endothelial surface glycocalyx modification greatly impairs the arteriogenic process. , 2015, American journal of physiology. Heart and circulatory physiology.

[31]  G. Gambaro,et al.  Impact of heparanase on renal fibrosis , 2015, Journal of Translational Medicine.

[32]  J. Holcomb,et al.  Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients , 2015, Journal of Translational Medicine.

[33]  T. Jenssen,et al.  Syndecan-4 Is a Major Syndecan in Primary Human Endothelial Cells In Vitro, Modulated by Inflammatory Stimuli and Involved in Wound Healing , 2015, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[34]  M. Goligorsky,et al.  Sirtuin 1 ablation in endothelial cells is associated with impaired angiogenesis and diastolic dysfunction. , 2014, American journal of physiology. Heart and circulatory physiology.

[35]  R. Foster,et al.  Matrix metalloproteinase 9‐mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[36]  M. Vogeser,et al.  Hypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyx , 2014, Critical Care.

[37]  S. Kersten Physiological regulation of lipoprotein lipase. , 2014, Biochimica et biophysica acta.

[38]  B. Brenner,et al.  Heparanase multiple effects in cancer. , 2014, Thrombosis research.

[39]  Linghong Huang,et al.  Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis. , 2014, Journal of the American Society of Nephrology : JASN.

[40]  R. R. Domingues,et al.  Deciphering the role of the ADAM17-dependent secretome in cell signaling. , 2014, Journal of proteome research.

[41]  M. Goligorsky,et al.  Endothelial sirtuin 1 deficiency perpetrates nephrosclerosis through downregulation of matrix metalloproteinase-14: relevance to fibrosis of vascular senescence. , 2014, Journal of the American Society of Nephrology : JASN.

[42]  J. Tarbell,et al.  Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. , 2014, American journal of physiology. Heart and circulatory physiology.

[43]  T. Rabelink,et al.  The role of heparanase and the endothelial glycocalyx in the development of proteinuria. , 2014, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[44]  M. Simpson,et al.  Emerging roles for hyaluronidase in cancer metastasis and therapy. , 2014, Advances in cancer research.

[45]  W. Sessa,et al.  Angiopoietin-2 Secretion by Endothelial Cell Exosomes , 2013, The Journal of Biological Chemistry.

[46]  T. Suuronen,et al.  Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. , 2013, Cellular signalling.

[47]  T. Rabelink,et al.  The endothelial glycocalyx as a potential modifier of the hemolytic uremic syndrome. , 2013, European journal of internal medicine.

[48]  D. Vynios,et al.  Hyaluronidases and their inhibitors in the serum of colorectal carcinoma patients. , 2013, Journal of pharmaceutical and biomedical analysis.

[49]  M. Simons,et al.  Syndecan-4 signaling at a glance , 2013, Journal of Cell Science.

[50]  R. Goldberg,et al.  Versatile role of heparanase in inflammation. , 2013, Matrix biology : journal of the International Society for Matrix Biology.

[51]  J. Li,et al.  Antithrombin is protective against myocardial ischemia and reperfusion injury , 2013, Journal of thrombosis and haemostasis : JTH.

[52]  John M Tarbell,et al.  Mechano‐sensing and transduction by endothelial surface glycocalyx: composition, structure, and function , 2013, Wiley interdisciplinary reviews. Systems biology and medicine.

[53]  C. Carlson,et al.  Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure‐overloaded heart , 2013, The FEBS journal.

[54]  Li Zhang,et al.  Negative regulation of inflammation by SIRT1. , 2013, Pharmacological research.

[55]  A. Thotakura,et al.  The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. , 2012, Trends in cell biology.

[56]  D. Spillmann,et al.  The Mutual Impact of Syndecan-1 and Its Glycosaminoglycan Chains—A Multivariable Puzzle , 2012, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[57]  Yimu Yang,et al.  The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis , 2012, Nature Medicine.

[58]  Johan Auwerx,et al.  Sirtuins as regulators of metabolism and healthspan , 2012, Nature Reviews Molecular Cell Biology.

[59]  Jin-ping Li,et al.  Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice , 2012, Neuroscience Letters.

[60]  M. Goligorsky,et al.  Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. , 2012, The American journal of pathology.

[61]  P. Park,et al.  Molecular functions of syndecan-1 in disease. , 2012, Matrix biology : journal of the International Society for Matrix Biology.

[62]  T. Annecke,et al.  Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion. , 2011, British journal of anaesthesia.

[63]  J. Esko,et al.  Heparan sulfate proteoglycans. , 2011, Cold Spring Harbor perspectives in biology.

[64]  Ashraf A Bakkar,et al.  Targeting hyaluronidase for cancer therapy: antitumor activity of sulfated hyaluronic acid in prostate cancer cells. , 2011, Cancer research.

[65]  L. Guarente Franklin H. Epstein Lecture: Sirtuins, aging, and medicine. , 2011, The New England journal of medicine.

[66]  Y. Matsui,et al.  Syndecan-4 Prevents Cardiac Rupture and Dysfunction After Myocardial Infarction , 2011, Circulation research.

[67]  T. Peretz,et al.  Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice. , 2011, The Journal of clinical investigation.

[68]  H. Lipowsky Protease Activity and the Role of the Endothelial Glycocalyx in Inflammation. , 2011, Drug discovery today. Disease models.

[69]  M. Christiaans,et al.  Acute ischemic injury to the renal microvasculature in human kidney transplantation. , 2010, American journal of physiology. Renal physiology.

[70]  J. Couchman,et al.  Transmembrane signaling proteoglycans. , 2010, Annual review of cell and developmental biology.

[71]  M. Jacob,et al.  Endothelial glycocalyx and coronary vascular permeability: the fringe benefit , 2010, Basic Research in Cardiology.

[72]  M. Gooz ADAM-17: the enzyme that does it all , 2010, Critical reviews in biochemistry and molecular biology.

[73]  M. Swellam,et al.  Expression of HYAL1 and survivin RNA as diagnostic molecular markers for bladder cancer. , 2010, The Journal of urology.

[74]  Vasilis Vasiliou,et al.  Evolutionary divergence and functions of the ADAM and ADAMTS gene families , 2009, Human Genomics.

[75]  H. van Goor,et al.  ADAM17 upregulation in human renal disease: a role in modulating TGF-alpha availability? , 2009, American journal of physiology. Renal physiology.

[76]  U. Welsch,et al.  Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion. , 2009, Cardiovascular research.

[77]  Michiyuki Matsuda,et al.  Suppression of RhoG activity is mediated by a syndecan 4–synectin–RhoGDI1 complex and is reversed by PKCα in a Rac1 activation pathway , 2009, The Journal of cell biology.

[78]  B. Walcheck,et al.  Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding1 , 2009, The Journal of Immunology.

[79]  E. Edelman,et al.  Heparanase Alters Arterial Structure, Mechanics, and Repair Following Endovascular Stenting in Mice , 2009, Circulation research.

[80]  G. Wong,et al.  Hyaluronan-mediated CD44 Interaction with p300 and SIRT1 Regulates β-Catenin Signaling and NFκB-specific Transcription Activity Leading to MDR1 and Bcl-xL Gene Expression and Chemoresistance in Breast Tumor Cells* , 2009, Journal of Biological Chemistry.

[81]  Paul N. Smith,et al.  Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis. , 2008, Arthritis and rheumatism.

[82]  N. J. Nasser Heparanase involvement in physiology and disease , 2008, Cellular and Molecular Life Sciences.

[83]  I. Poola,et al.  Molecular Risk Assessment for Breast Cancer Development in Patients with Ductal Hyperplasias , 2008, Clinical Cancer Research.

[84]  F. Alt,et al.  SIRT1 controls endothelial angiogenic functions during vascular growth. , 2007, Genes & development.

[85]  Francis G Spinale,et al.  Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. , 2007, Physiological reviews.

[86]  J. Kastelein,et al.  Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis , 2007, Diabetologia.

[87]  C. Hansch,et al.  Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. , 2007, Bioorganic & medicinal chemistry.

[88]  Dick W. Slaaf,et al.  The endothelial glycocalyx: composition, functions, and visualization , 2007, Pflügers Archiv - European Journal of Physiology.

[89]  P. Raynaud,et al.  Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma. , 2006, Blood.

[90]  A. Brasier The NF-κB regulatory network , 2007, Cardiovascular Toxicology.

[91]  M. Sperandio Selectins and glycosyltransferases in leukocyte rolling in vivo , 2006, The FEBS journal.

[92]  T. Peretz,et al.  Role of endothelial heparanase in delayed-type hypersensitivity. , 2006, Blood.

[93]  R. Heine,et al.  Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes. , 2006, Diabetes.

[94]  A. Brasier The NF-kappaB regulatory network. , 2006, Cardiovascular toxicology.

[95]  Hans Vink,et al.  The endothelial glycocalyx: a potential barrier between health and vascular disease , 2005, Current opinion in lipidology.

[96]  P. E. Van den Steen,et al.  Targeting neutrophil collagenase/matrix metalloproteinase-8 and gelatinase B/matrix metalloproteinase-9 with a peptidomimetic inhibitor protects against endotoxin shock. , 2005, Biochemical pharmacology.

[97]  Satoshi O. Suzuki,et al.  Clinical Significance of Heparin-Binding Epidermal Growth Factor–Like Growth Factor and A Disintegrin and Metalloprotease 17 Expression in Human Ovarian Cancer , 2005, Clinical Cancer Research.

[98]  M. Kawaguchi,et al.  Overexpression of tumour necrosis factor‐α‐converting enzyme in psoriasis , 2005 .

[99]  J. Platt,et al.  Conditional signaling by Toll‐like receptor 4 , 2005, The FASEB Journal.

[100]  E. Tkachenko,et al.  Syndecans: new kids on the signaling block. , 2005, Circulation research.

[101]  M. Mayo,et al.  Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase , 2004, The EMBO journal.

[102]  M. Karin,et al.  The two NF-κB activation pathways and their role in innate and adaptive immunity , 2004 .

[103]  Guangping Chen,et al.  Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression. , 2004, Biochemistry.

[104]  Steven P. Gygi,et al.  Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase , 2004, Science.

[105]  Delin Chen,et al.  Mammalian SIRT1 Represses Forkhead Transcription Factors , 2004, Cell.

[106]  A. Mulivor,et al.  Inflammation- and ischemia-induced shedding of venular glycocalyx. , 2004, American journal of physiology. Heart and circulatory physiology.

[107]  M. Karin,et al.  The two NF-kappaB activation pathways and their role in innate and adaptive immunity. , 2004, Trends in immunology.

[108]  F. Zhan,et al.  High heparanase activity in multiple myeloma is associated with elevated microvessel density. , 2003, Cancer research.

[109]  J. Couchman Syndecans: proteoglycan regulators of cell-surface microdomains? , 2003, Nature Reviews Molecular Cell Biology.

[110]  Jeffry A Florian,et al.  Heparan Sulfate Proteoglycan Is a Mechanosensor on Endothelial Cells , 2003, Circulation research.

[111]  T. Yoshizaki,et al.  Cleavage of Syndecan-1 by Membrane Type Matrix Metalloproteinase-1 Stimulates Cell Migration* , 2003, Journal of Biological Chemistry.

[112]  B. Duling,et al.  Rapid modification of the glycocalyx caused by ischemia-reperfusion is inhibited by adenosine A2A receptor activation. , 2003, American journal of physiology. Heart and circulatory physiology.

[113]  J. Baselga,et al.  TACE is required for the activation of the EGFR by TGF‐α in tumors , 2003 .

[114]  J. Baselga,et al.  TACE is required for the activation of the EGFR by TGF-alpha in tumors. , 2003, The EMBO journal.

[115]  Vincenza Dolo,et al.  Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. , 2002, The American journal of pathology.

[116]  K. Shimamoto,et al.  Effect of TNF-α–Converting Enzyme Inhibitor on Insulin Resistance in Fructose-Fed Rats , 2002 .

[117]  K. Shimamoto,et al.  Effect of TNF-alpha--converting enzyme inhibitor on insulin resistance in fructose-fed rats. , 2002, Hypertension.

[118]  H. Saito,et al.  Syndecan-4 Deficiency Leads to High Mortality of Lipopolysaccharide-injected Mice* , 2001, The Journal of Biological Chemistry.

[119]  N. Kamatani,et al.  Tumor necrosis factor-alpha (TNF-alpha) converting enzyme contributes to production of TNF-alpha in synovial tissues from patients with rheumatoid arthritis. , 2001, The Journal of rheumatology.

[120]  M. Detmar,et al.  Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4. , 2001, The Journal of clinical investigation.

[121]  Z. Werb,et al.  How matrix metalloproteinases regulate cell behavior. , 2001, Annual review of cell and developmental biology.

[122]  A. Nandi,et al.  Hyaluronan Anchoring and Regulation on the Surface of Vascular Endothelial Cells Is Mediated through the Functionally Active Form of CD44* , 2000, The Journal of Biological Chemistry.

[123]  T. W. Secomb,et al.  The endothelial surface layer , 2000, Pflügers Archiv.

[124]  S. Tumova,et al.  Heparan Sulfate Chains from Glypican and Syndecans Bind the Hep II Domain of Fibronectin Similarly Despite Minor Structural Differences* , 2000, The Journal of Biological Chemistry.

[125]  B. Duling,et al.  Permeation of the luminal capillary glycocalyx is determined by hyaluronan. , 1999, American journal of physiology. Heart and circulatory physiology.

[126]  R. Frye,et al.  Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. , 1999, Biochemical and biophysical research communications.

[127]  J. Harlan,et al.  Adhesion of Activated Platelets to Endothelial Cells: Evidence for a GPIIbIIIa-dependent Bridging Mechanism and Novel Roles for Endothelial Intercellular Adhesion Molecule 1 (ICAM-1), αvβ3 Integrin, and GPIbα , 1998, The Journal of experimental medicine.

[128]  G. Ghosh,et al.  Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA , 1998, Nature.

[129]  M J May,et al.  NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.

[130]  Klaus Ley,et al.  Regulation of E‐Selectin, P‐Selectin, and Intercellular Adhesion Molecule 1 Expression in Mouse Cremaster Muscle Vasculature , 1997, Microcirculation.

[131]  H. V. Van Wart,et al.  Hydrolysis of a Broad Spectrum of Extracellular Matrix Proteins by Human Macrophage Elastase* , 1997, The Journal of Biological Chemistry.

[132]  R. Gallo,et al.  Syndecans-1 and -4 are induced during wound repair of neonatal but not fetal skin. , 1996, The Journal of investigative dermatology.

[133]  W. Graber,et al.  Association of hyaluronan with rat vascular endothelial and smooth muscle cells. , 1995, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[134]  B. Feldt-Rasmussen,et al.  Effect of low-dose heparin on urinary albumin excretion in insulin-dependent diabetes mellitus , 1995, The Lancet.

[135]  Choll W. Kim,et al.  Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns. , 1994, Molecular biology of the cell.

[136]  B. F. Becker Towards the physiological function of uric acid. , 1993, Free radical biology & medicine.

[137]  M. Laato,et al.  Induced expression of syndecan in healing wounds , 1991, The Journal of cell biology.

[138]  T. Deckert,et al.  Possible Genetic Defects in Regulation of Glycosaminoglycans in Patients With Diabetic Nephropathy , 1991, Diabetes.