Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival
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Wing-Kin Sung | Edwin Cheung | Cheng Wei Chang | Kern Rei Chng | W. Sung | E. Cheung | Peck Yean Tan | K. S. A. Wansa | K. D. Senali Abayratna Wansa
[1] Cheng Wei Chang,et al. AP‐2γ regulates oestrogen receptor‐mediated long‐range chromatin interaction and gene transcription , 2011, The EMBO journal.
[2] Wing-Kin Sung,et al. CENTDIST: discovery of co-associated factors by motif distribution , 2011, Nucleic Acids Res..
[3] C. Glass,et al. Reprogramming Transcription via Distinct Classes of Enhancers Functionally Defined by eRNA , 2011, Nature.
[4] E. Montgomery,et al. NKX3.1 as a Marker of Prostatic Origin in Metastatic Tumors , 2010, The American journal of surgical pathology.
[5] O. De Wever,et al. Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis. , 2010, Journal of the National Cancer Institute.
[6] Zhaohui S. Qin,et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. , 2010, Cancer cell.
[7] Feng Lin,et al. A signal-noise model for significance analysis of ChIP-seq with negative control , 2010, Bioinform..
[8] Saraswati Sukumar,et al. The Hox genes and their roles in oncogenesis , 2010, Nature Reviews Cancer.
[9] Clifford A. Meyer,et al. Nucleosome Dynamics Define Transcriptional Enhancers , 2010, Nature Genetics.
[10] E. Cheung,et al. Genomic analyses of hormone signaling and gene regulation. , 2010, Annual review of physiology.
[11] Daehee Hwang,et al. Integrated Expression Profiling and ChIP-seq Analyses of the Growth Inhibition Response Program of the Androgen Receptor , 2009, PloS one.
[12] M. Shen,et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer , 2009, Nature.
[13] H. Aburatani,et al. Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. , 2009, Cancer research.
[14] N. Kyprianou,et al. Androgen receptor and growth factor signaling cross-talk in prostate cancer cells. , 2008, Endocrine-related cancer.
[15] G. Coetzee,et al. Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity , 2008, PloS one.
[16] D. Tindall,et al. Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancer. , 2008, Cancer research.
[17] R. Shamir,et al. Transcription factor and microRNA motif discovery: the Amadeus platform and a compendium of metazoan target sets. , 2008, Genome research.
[18] E. Gelmann,et al. R E V Ie W a Rt I C L E , 2022 .
[19] W. Schulz,et al. Functional analysis of NKX3.1 in LNCaP prostate cancer cells by RNA interference. , 2008, International journal of oncology.
[20] Clifford A. Meyer,et al. FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription , 2008, Cell.
[21] A. Jemal,et al. Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.
[22] Z. Shao,et al. Enhanced Expression of Rab27A Gene by Breast Cancer Cells Promoting Invasiveness and the Metastasis Potential by Secretion of Insulin-Like Growth Factor-II , 2008, Molecular Cancer Research.
[23] D. Tindall,et al. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. , 2007, Endocrine reviews.
[24] A. Morin,et al. SIRNA-Directed In Vivo Silencing of Androgen Receptor Inhibits the Growth of Castration-Resistant Prostate Carcinomas , 2007, PloS one.
[25] S. Abdulkadir,et al. Haploinsufficient Prostate Tumor Suppression by Nkx3.1 , 2007, Journal of Biological Chemistry.
[26] I. Mills,et al. New androgen receptor genomic targets show an interaction with the ETS1 transcription factor , 2007, EMBO reports.
[27] Hao Li,et al. Cell- and gene-specific regulation of primary target genes by the androgen receptor. , 2007, Genes & development.
[28] K. Pienta,et al. A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. , 2007, Molecular cell.
[29] C. Bieberich,et al. Immunohistochemical Differentiation of High-grade Prostate Carcinoma From Urothelial Carcinoma , 2007, The American journal of surgical pathology.
[30] H. Aburatani,et al. Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis , 2007, Oncogene.
[31] P. Rennie,et al. Short hairpin RNA knockdown of the androgen receptor attenuates ligand-independent activation and delays tumor progression. , 2006, Cancer research.
[32] D. Tindall,et al. Molecular regulation of androgen action in prostate cancer , 2006, Journal of cellular biochemistry.
[33] Clifford A. Meyer,et al. Genome-wide analysis of estrogen receptor binding sites , 2006, Nature Genetics.
[34] M. Gleave,et al. NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. , 2006, Cancer cell.
[35] C. Bieberich,et al. Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion. , 2006, Cancer research.
[36] H. Naora,et al. Homeobox gene expression in cancer: insights from developmental regulation and deregulation. , 2005, European journal of cancer.
[37] R. Schwartz,et al. Regulation of organ development by the NKX-homeodomain factors: an NKX code. , 2005, Cellular and molecular biology.
[38] J. Thrasher,et al. Small-interfering RNA–induced androgen receptor silencing leads to apoptotic cell death in prostate cancer , 2005, Molecular Cancer Therapeutics.
[39] G. Mills,et al. Emerging role of RAB GTPases in cancer and human disease. , 2005, Cancer research.
[40] E. Gelmann,et al. Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer. , 2005, Cancer research.
[41] Qing Yang,et al. Androgen receptor signaling is required for androgen-sensitive human prostate cancer cell proliferation and survival , 2005, Cancer Cell International.
[42] B. Gary,et al. Interaction of Nkx3.1 and p27kip1 in prostate tumor initiation. , 2004, The American journal of pathology.
[43] R. Aebersold,et al. Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. , 2003, Molecular endocrinology.
[44] Renjie Jin,et al. The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes. , 2003, Molecular endocrinology.
[45] F. Nunes,et al. Homeobox genes: a molecular link between development and cancer. , 2003, Pesquisa odontologica brasileira = Brazilian oral research.
[46] Jeffrey A. Magee,et al. Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation. , 2003, Cancer cell.
[47] E. Gelmann,et al. Molecular biology of the androgen receptor. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[48] C. Heinlein,et al. Androgen receptor (AR) coregulators: an overview. , 2002, Endocrine reviews.
[49] Neil J. McKenna,et al. Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators , 2002, Cell.
[50] D. Tindall,et al. Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. , 2002, Cancer research.
[51] H. Klocker,et al. Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor , 2002, Cancer Gene Therapy.
[52] T. Visakorpi,et al. Molecular genetics of prostate cancer. , 2003, Annals of medicine.
[53] D. Feldman,et al. The development of androgen-independent prostate cancer , 2001, Nature Reviews Cancer.
[54] F. Claessens,et al. Selective DNA binding by the androgen receptor as a mechanism for hormone-specific gene regulation , 2001, The Journal of Steroid Biochemistry and Molecular Biology.
[55] E. Bruckheimer,et al. Dihydrotestosterone enhances transforming growth factor-beta-induced apoptosis in hormone-sensitive prostate cancer cells. , 2001, Endocrinology.
[56] T. Pretlow,et al. Full-length cDNA sequence and genomic organization of human NKX3A - alternative forms and regulation by both androgens and estrogens. , 2000, Gene.
[57] H. Klocker,et al. Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides , 2000, Cancer Gene Therapy.
[58] A. Belldegrun,et al. Evidence for clonal outgrowth of androgen-independent prostate cancer cells from androgen-dependent tumors through a two-step process. , 1999, Cancer research.
[59] R. Cardiff,et al. Roles for Nkx3.1 in prostate development and cancer. , 1999, Genes & development.
[60] C S Song,et al. Regulation of androgen action. , 1999, Vitamins and hormones.
[61] D. Tindall,et al. Isolation and androgen regulation of the human homeobox cDNA, NKX3.1 , 1998, The Prostate.
[62] C. Chiang,et al. Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression , 1998, Mechanisms of Development.
[63] R. T. Curtis,et al. A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer. , 1997, Genomics.
[64] M. Shen,et al. Tissue‐specific expression of murine Nkx3.1 in the male urogenital system , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.
[65] G. Duchesne,et al. Androgens and prostate cancer: biology, pathology and hormonal therapy. , 1997, European journal of cancer.
[66] C. Bieberich,et al. Prostate-specific and Androgen-dependent Expression of a Novel Homeobox Gene* , 1996, The Journal of Biological Chemistry.
[67] M. Beato,et al. Interaction of steroid hormone receptors with the transcription initiation complex. , 1996, Endocrine reviews.
[68] L. Liotta,et al. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12-21. , 1996, Cancer research.
[69] K. Kirk,et al. Distinct Functional Properties of Rab3A and Rab3B in PC12 Neuroendocrine Cells (*) , 1996, The Journal of Biological Chemistry.
[70] Chawnshang Chang,et al. The androgen receptor: a mediator of diverse responses. , 1996, Frontiers in bioscience : a journal and virtual library.
[71] D. Grabs,et al. Rab3 Proteins and SNAP‐25, Essential Components of the Exocytosis Machinery in Conventional Synapses, are Absent from Ribbon Synapses of the Mouse Retina , 1996, The European journal of neuroscience.
[72] J. Trapman,et al. The androgen receptor in prostate cancer. , 1996, Pathology, research and practice.
[73] F. Bosman,et al. Loss of heterozygosity of chromosome 8 microsatellite loci implicates a candidate tumor suppressor gene between the loci D8S87 and D8S133 in human prostate cancer. , 1994, Cancer research.
[74] E. Wilson,et al. The androgen receptor: an overview. , 1994, Recent progress in hormone research.
[75] J. Vincent,et al. Inhibition of RabSB expression attenuates Ca2+-dependent exocytosis in rat anterior pituitary cells , 1993, Nature.
[76] J. Vincent,et al. Inhibition of Rab3B expression attenuates Ca(2+)-dependent exocytosis in rat anterior pituitary cells. , 1993, Nature.
[77] U. Bergerheim,et al. Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma , 1991, Genes, chromosomes & cancer.
[78] S. J. Higgins,et al. The endocrinology and developmental biology of the prostate. , 1987, Endocrine reviews.