Effect of Cepharanthin on Superoxide Anion (O2–) Production by Macrophages

Our previous report showed the inhibitory action of cepharanthin on oxygen‐derived free radical production by polymorphonuclear leukocytes (PMN). In the present study, we examined the effects of cepharanthin on production of superoxide anion (O2–), one oxygen radical, by macrophages in vitro and in vivo.