Significance of risk polymorphisms for depression depends on stress exposure

[1]  N. Ferreira.  Emerging approaches , 2019, Psychogastroenterology for Adults.

[2]  I. Everall,et al.  Polygenic phenotypic plasticity moderates the effects of severe childhood abuse on depressive symptom severity in adulthood: A 5-year prospective cohort study , 2017, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[3]  D. Hinds,et al.  Identification of 15 genetic loci associated with risk of major depression in individuals of European descent , 2016, Nature Genetics.

[4]  K. Ressler,et al.  GENOME‐WIDE ASSOCIATION STUDY (GWAS) AND GENOME‐WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN , 2016, Depression and anxiety.

[5]  B. Bradley,et al.  Gene × Environment Determinants of Stress- and Anxiety-Related Disorders. , 2016, Annual review of psychology.

[6]  Adrian E. Raftery,et al.  Bayesian Model Averaging: A Tutorial , 2016 .

[7]  J. Potash,et al.  Polygenic interactions with environmental adversity in the aetiology of major depressive disorder , 2015, Psychological Medicine.

[8]  R. Elliott,et al.  Variability in the Effect of 5-HTTLPR on Depression in a Large European Population: The Role of Age, Symptom Profile, Type and Intensity of Life Stressors , 2015, PloS one.

[9]  Laura J. Scott,et al.  Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways , 2015, Nature Neuroscience.

[10]  Ruth C. Brown,et al.  Genetic Determinants of Depression: Recent Findings and Future Directions , 2015, Harvard review of psychiatry.

[11]  K. Kendler,et al.  Candidate Gene–Environment Interaction Research , 2015, Perspectives on psychological science : a journal of the Association for Psychological Science.

[12]  P. Zandi,et al.  Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis , 2014, Psychological Medicine.

[13]  Yanbo Zhang,et al.  Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice , 2014, Brain Research.

[14]  Isaac S Kohane,et al.  Deeper, longer phenotyping to accelerate the discovery of the genetic architectures of diseases , 2014, Genome Biology.

[15]  Peter Antal,et al.  Brain galanin system genes interact with life stresses in depression-related phenotypes , 2014, Proceedings of the National Academy of Sciences.

[16]  Rudolf Uher,et al.  Gene–Environment Interactions in Severe Mental Illness , 2014, Front. Psychiatry.

[17]  J. Belsky.  Differential Susceptibility to Environmental Influences , 2013 .

[18]  M. Kabbaj,et al.  The consequences of adolescent chronic unpredictable stress exposure on brain and behavior , 2013, Neuroscience.

[19]  John P. Rice,et al.  Genome‐wide association analysis accounting for environmental factors through propensity‐score matching: Application to stressful live events in major depressive disorder , 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[20]  Peter Antal,et al.  The effect of parameter priors on Bayesian relevance and effect size measures , 2013 .

[21]  Peter Willett,et al.  What is a tutorial , 2013 .

[22]  S. Sen,et al.  Gene × environment interaction models in psychiatric genetics. , 2012, Current topics in behavioral neurosciences.

[23]  K. Domschke,et al.  Behavioral genetics of affective and anxiety disorders. , 2012, Current topics in behavioral neurosciences.

[24]  R. Uher,et al.  Gene–Environment Interaction in Major Depression and Antidepressant Treatment Response , 2012, Current Psychiatry Reports.

[25]  A. Caspi,et al.  Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results. , 2011, Journal of affective disorders.

[26]  K. Shedden,et al.  The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. , 2011, Archives of general psychiatry.

[27]  P. Terpstra,et al.  Poor replication of candidate genes for major depressive disorder using genome-wide association data , 2011, Molecular Psychiatry.

[28]  R. Elliott,et al.  The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions , 2011, Biological Psychiatry.

[29]  G. Plazzi,et al.  A 5-year prospective cohort study on health-related quality of life in patients with narcolepsy. , 2011, Sleep medicine.

[30]  E. Nestler,et al.  Animal models of depression: molecular perspectives. , 2011, Current topics in behavioral neurosciences.

[31]  E. Nestler,et al.  Linking molecules to mood: new insight into the biology of depression. , 2010, The American journal of psychiatry.

[32]  G. Juhász,et al.  Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor gene , 2010, European Neuropsychopharmacology.

[33]  Qiong Yang,et al.  Analyze multivariate phenotypes in genetic association studies by combining univariate association tests , 2010, Genetic epidemiology.

[34]  D. Thomas,et al.  Gene–environment-wide association studies: emerging approaches , 2010, Nature Reviews Genetics.

[35]  G. Juhász,et al.  Significant association between the C(−1019)G functional polymorphism of the HTR1A gene and impulsivity , 2010, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[36]  K. Shedden,et al.  Evidence of Genetic Moderation , 2010 .

[37]  Jay Belsky,et al.  Beyond diathesis stress: differential susceptibility to environmental influences. , 2009, Psychological bulletin.

[38]  Rebecca Elliott,et al.  CNR1 Gene is Associated with High Neuroticism and Low Agreeableness and Interacts with Recent Negative Life Events to Predict Current Depressive Symptoms , 2009, Neuropsychopharmacology.

[39]  S. Fuller,et al.  Genetics of the P2X7 receptor and human disease , 2009, Purinergic Signalling.

[40]  Avshalom Caspi,et al.  Gene-environment interplay and psychopathology: multiple varieties but real effects. , 2006, Journal of child psychology and psychiatry, and allied disciplines.

[41]  Gregory F. Cooper,et al.  A Bayesian method for the induction of probabilistic networks from data , 1992, Machine Learning.

[42]  Paolo Giudici,et al.  Improving Markov Chain Monte Carlo Model Search for Data Mining , 2004, Machine Learning.

[43]  Nir Friedman,et al.  Being Bayesian About Network Structure. A Bayesian Approach to Structure Discovery in Bayesian Networks , 2004, Machine Learning.

[44]  A. Wilkie,et al.  Faculty Opinions recommendation of Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. , 2003 .

[45]  B. Freeman,et al.  DNA from Buccal Swabs Recruited by Mail: Evaluation of Storage Effects on Long-Term Stability and Suitability for Multiplex Polymerase Chain Reaction Genotyping , 2003, Behavior genetics.

[46]  A. Caspi,et al.  Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene , 2003, Science.

[47]  M. Rutter,et al.  Gene–environment interplay in relation to emotional and behavioural disturbance , 2002, European Psychiatry.

[48]  M. Palkovits,et al.  Stressor specificity of central neuroendocrine responses: implications for stress-related disorders. , 2001, Endocrine reviews.

[49]  P. Sullivan,et al.  Genetic epidemiology of major depression: review and meta-analysis. , 2000, The American journal of psychiatry.

[50]  Adrian E. Raftery,et al.  Bayesian model averaging: a tutorial (with comments by M. Clyde, David Draper and E. I. George, and a rejoinder by the authors , 1999 .

[51]  K. Bird.  Reflections and Recommendations , 1997 .

[52]  C. Judd,et al.  Statistical difficulties of detecting interactions and moderator effects. , 1993, Psychological bulletin.

[53]  A. Simons,et al.  Diathesis-stress theories in the context of life stress research: implications for the depressive disorders. , 1991, Psychological bulletin.

[54]  A. Bifulco,et al.  Life Events, Vulnerability and Onset of Depression , 1987, British Journal of Psychiatry.

[55]  T. Brugha,et al.  The List of Threatening Experiences: a subset of 12 life event categories with considerable long-term contextual threat , 1985, Psychological Medicine.