Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer

[1]  M. Koch,et al.  Overexpression of SIX1 is an independent prognostic marker in stage I–III colorectal cancer , 2015, International journal of cancer.

[2]  H. Ford,et al.  TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation. , 2015, Cancer research.

[3]  Lijuan Lin,et al.  Sineoculis homeobox homolog 1 protein overexpression as an independent biomarker for pancreatic ductal adenocarcinoma. , 2014, Experimental and molecular pathology.

[4]  Zhaoming Li,et al.  Six1 Promotes Proliferation of Pancreatic Cancer Cells via Upregulation of Cyclin D1 Expression , 2013, PloS one.

[5]  J. Inazawa,et al.  SIX1 promotes epithelial–mesenchymal transition in colorectal cancer through ZEB1 activation , 2012, Oncogene.

[6]  Jean Paul Thiery,et al.  Early events in cell adhesion and polarity during epithelial-mesenchymal transition , 2012, Journal of Cell Science.

[7]  M. Koch,et al.  Expression Analysis of Aldehyde Dehydrogenase 1A1 (ALDH1A1) in Colon and Rectal Cancer in Association with Prognosis and Response to Chemotherapy , 2012, Annals of Surgical Oncology.

[8]  T. Brabletz.  To differentiate or not — routes towards metastasis , 2012, Nature Reviews Cancer.

[9]  Jie-xiong Tan,et al.  Expression and significance of Six1 and Ezrin in cervical cancer tissue , 2011, Tumor Biology.

[10]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[11]  Alberto Martin,et al.  Tumorigenesis: Twist1 links EMT to self-renewal , 2010, Nature Cell Biology.

[12]  Ying-ru Zheng,et al.  Expression and Clinical Implications of Homeobox Gene Six1 in Cervical Cancer Cell Lines and Cervical Epithelial Tissues , 2010, International Journal of Gynecologic Cancer.

[13]  S. Fan,et al.  Suppression of tumorigenesis and metastasis of hepatocellular carcinoma by shRNA interference targeting on homeoprotein Six1 , 2010, International journal of cancer.

[14]  H. Ford,et al.  Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression , 2010, Journal of Mammary Gland Biology and Neoplasia.

[15]  D. D. Billheimer,et al.  The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. , 2009, The Journal of clinical investigation.

[16]  H. Ford,et al.  Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.

[17]  Gerhard Christofori,et al.  EMT, the cytoskeleton, and cancer cell invasion , 2009, Cancer and Metastasis Reviews.

[18]  H. Ford,et al.  Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival. , 2007, Cancer research.

[19]  P. Dalerba,et al.  Identification of pancreatic cancer stem cells. , 2006, Cancer research.

[20]  Thomas Kirchner,et al.  Invasion and Metastasis in Colorectal Cancer: Epithelial-Mesenchymal Transition, Mesenchymal-Epithelial Transition, Stem Cells and β-Catenin , 2005, Cells Tissues Organs.

[21]  L. Solnica-Krezel.  Conserved Patterns of Cell Movements during Vertebrate Gastrulation , 2005, Current Biology.

[22]  E. Hay,et al.  Transforming growth factor β (TGFβ) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT) , 2004 .

[23]  R. Tucker.  Neural crest cells: a model for invasive behavior. , 2004, The international journal of biochemistry & cell biology.

[24]  S. Morrison,et al.  Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[25]  M. Pfaffl,et al.  A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.

[26]  R. DePinho,et al.  Cellular Senescence Minireview Mitotic Clock or Culture Shock? , 2000, Cell.

[27]  M. Carmell,et al.  Posttranscriptional Gene Silencing in Plants , 2006 .

[28]  H. Ford,et al.  Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[29]  S. Holmen,et al.  Efficient lipid-mediated transfection of DNA into primary rat hepatocytes , 1995, In Vitro Cellular & Developmental Biology - Animal.

[30]  A. Jemal,et al.  Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.

[31]  E. Hay,et al.  Transforming growth factor beta (TGFbeta) signalling in palatal growth, apoptosis and epithelial mesenchymal transformation (EMT). , 2004, Archives of oral biology.

[32]  Henry A. Erlich,et al.  The polymerase chain reaction. , 1989, Trends in genetics : TIG.

[33]  K. Mullis,et al.  Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction. , 1986, Cold Spring Harbor symposia on quantitative biology.

[34]  N. Dubrawsky.  Cancer statistics , 2022 .