Overexpression of Purinergic P2X4 Receptors in Hippocampus Rescues Memory Impairment in Rats with Type 2 Diabetes

[1]  Daishi Tian,et al.  Microglial P2Y12 receptor regulates ventral hippocampal CA1 neuronal excitability and innate fear in mice , 2019, Molecular Brain.

[2]  L. Bergantin.  Debating the “bidirectional link” between diabetes and depression through the Ca2+/cAMP signalling: Off‐label effects of Ca2+ channel blockers , 2019, Pharmacological research.

[3]  F. Koch-Nolte,et al.  P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis , 2018, EMBO molecular medicine.

[4]  K. Paller,et al.  Retrieval and sleep both counteract the forgetting of spatial information , 2018, Learning & memory.

[5]  G. Forloni,et al.  Novel targets in Alzheimer's disease: A special focus on microglia. , 2018, Pharmacological research.

[6]  Lina Xu,et al.  Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms , 2018, Pharmacological research.

[7]  Xiong Wang,et al.  Tau-Induced Ca2+/Calmodulin-Dependent Protein Kinase-IV Activation Aggravates Nuclear Tau Hyperphosphorylation , 2017, Neuroscience Bulletin.

[8]  Ji Zhang,et al.  Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain , 2018, Molecular pain.

[9]  M. Tsuda.  Modulation of Pain and Itch by Spinal Glia , 2017, Neuroscience Bulletin.

[10]  N. Ozaki,et al.  CCR2 upregulation in DRG neurons plays a crucial role in gastric hyperalgesia associated with diabetic gastropathy , 2018, Molecular pain.

[11]  Jinrong Wei,et al.  Upregulation of Spinal Voltage-Dependent Anion Channel 1 Contributes to Bone Cancer Pain Hypersensitivity in Rats , 2017, Neuroscience Bulletin.

[12]  Zheng-Xiong Xi,et al.  Local Cues Establish and Maintain Region-Specific Phenotypes of Basal Ganglia Microglia , 2017, Neuron.

[13]  Z. Xiang,et al.  MiR-30a Positively Regulates the Inflammatory Response of Microglia in Experimental Autoimmune Encephalomyelitis , 2017, Neuroscience Bulletin.

[14]  Xiaofang Shi,et al.  Effects of Single and Repeated Exposure to a 50-Hz 2-mT Electromagnetic Field on Primary Cultured Hippocampal Neurons , 2017, Neuroscience Bulletin.

[15]  Guang-Yin Xu,et al.  Neonatal Maternal Deprivation Enhances Presynaptic P2X7 Receptor Transmission in Insular Cortex in an Adult Rat Model of Visceral Hypersensitivity , 2017, CNS neuroscience & therapeutics.

[16]  Lingling Zhu,et al.  WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation , 2017, Neuroscience Bulletin.

[17]  R. Sandhir,et al.  Fractal dimensions: A new paradigm to assess spatial memory and learning using Morris water maze , 2016, Behavioural Brain Research.

[18]  Joel N. Meyer,et al.  PCR‐Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage , 2016, Current protocols in toxicology.

[19]  M. Xie,et al.  Rho-Associated Kinase Inhibitors Promote Microglial Uptake Via the ERK Signaling Pathway , 2016, Neuroscience Bulletin.

[20]  M. Duarte,et al.  Oxidative DNA damage is associated with inflammatory response, insulin resistance and microvascular complications in type 2 diabetes. , 2015, Mutation research.

[21]  G. Biessels,et al.  Hippocampal insulin resistance and cognitive dysfunction , 2015, Nature Reviews Neuroscience.

[22]  J. Weaver,et al.  Activation of matrix metalloproteinase in dorsal hippocampus drives improvement in spatial working memory after intra‐VTA nicotine infusion in rats , 2015, Journal of neurochemistry.

[23]  Xinghong Jiang,et al.  Promoted Interaction of Nuclear Factor-κB With Demethylated Purinergic P2X3 Receptor Gene Contributes to Neuropathic Pain in Rats With Diabetes , 2015, Diabetes.

[24]  Jinrong Wei,et al.  Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats , 2015, Pain.

[25]  Q. Pittman,et al.  Microglia-Dependent Alteration of Glutamatergic Synaptic Transmission and Plasticity in the Hippocampus during Peripheral Inflammation , 2015, The Journal of Neuroscience.

[26]  Ukpong B. Eyo,et al.  Modulation of Microglial Process Convergence Toward Neuronal Dendrites by Extracellular Calcium , 2015, The Journal of Neuroscience.

[27]  L. Formigli,et al.  Minocycline But Not Tigecycline Is Neuroprotective and Reduces the Neuroinflammatory Response Induced by the Superimposition of Sepsis Upon Traumatic Brain Injury* , 2014, Critical care medicine.

[28]  M. Donath.  Targeting inflammation in the treatment of type 2 diabetes: time to start , 2014, Nature Reviews Drug Discovery.

[29]  C. Davis,et al.  Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity , 2014, The Journal of Neuroscience.

[30]  J. Llop,et al.  P2X4 receptors control the fate and survival of activated microglia , 2014, Glia.

[31]  J. Shaw,et al.  Global estimates of diabetes prevalence for 2013 and projections for 2035. , 2014, Diabetes Research and Clinical Practice.

[32]  K. Clarke,et al.  Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin , 2013, Cardiovascular Diabetology.

[33]  B. Winblad,et al.  Diabetes, Alzheimer disease, and vascular dementia A population-based neuropathologic study , 2013 .

[34]  A. Bhansali,et al.  Diabetes mellitus and risk of dementia: A meta‐analysis of prospective observational studies , 2013, Journal of diabetes investigation.

[35]  Letisha R. Wyatt,et al.  Sociocommunicative and Sensorimotor Impairments in Male P2X4-Deficient Mice , 2013, Neuropsychopharmacology.

[36]  C. Matute,et al.  Neurotransmitter signaling in the pathophysiology of microglia , 2013, Front. Cell. Neurosci..

[37]  J. Cadet,et al.  Oxidatively generated complex DNA damage: tandem and clustered lesions. , 2012, Cancer letters.

[38]  Guy C. Brown,et al.  Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling , 2012, Journal of Neuroinflammation.

[39]  B. Frier,et al.  Diabetes and cognitive dysfunction , 2012, The Lancet.

[40]  R. North,et al.  Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons , 2011, The European journal of neuroscience.

[41]  B. Winblad,et al.  Diabetes, Alzheimer disease, and vascular dementia , 2010, Neurology.

[42]  P. M. Hwang,et al.  Mitochondrial respiration protects against oxygen-associated DNA damage. , 2010, Nature communications.

[43]  Charles D. Smith,et al.  Human cerebral neuropathology of Type 2 diabetes mellitus. , 2009, Biochimica et biophysica acta.

[44]  I. Deary,et al.  Cognition and diabetes: a lifespan perspective , 2008, The Lancet Neurology.

[45]  David A. Bennett,et al.  Mixed brain pathologies account for most dementia cases in community-dwelling older persons , 2007, Neurology.

[46]  R. North,et al.  Altered Hippocampal Synaptic Potentiation in P2X4 Knock-Out Mice , 2006, The Journal of Neuroscience.

[47]  F. Helmchen,et al.  Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo , 2005, Science.

[48]  D. Bennett,et al.  Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. , 2004, Archives of neurology.

[49]  S. Koizumi,et al.  P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury , 2003, Nature.

[50]  S. B. Kater,et al.  ATP Released from Astrocytes Mediates Glial Calcium Waves , 1999, The Journal of Neuroscience.

[51]  T. Lindahl.  Instability and decay of the primary structure of DNA , 1993, Nature.

[52]  Daishi Tian,et al.  Dual Functions of Microglia in Ischemic Stroke , 2019, Neuroscience Bulletin.

[53]  M. Mattson,et al.  TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury. , 2017, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[54]  J. Tost.  Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns. , 2016, Advances in experimental medicine and biology.

[55]  张弘弘,et al.  Promoted Interaction of Nuclear Factor-kB With Demethylated Purinergic P2X3 Receptor Gene Contributes to Neuropathic Pain in Rats With Diabetes , 2015 .