Nutrient sensing modulates malaria parasite virulence

[1]  M. Berriman,et al.  Complete avian malaria parasite genomes reveal host-specific parasite evolution in birds and mammals , 2016, bioRxiv.

[2]  Gretchen A. Stevens,et al.  Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants , 2016, The Lancet.

[3]  D. Sabatini,et al.  Nutrient-Sensing Mechanisms across Evolution , 2015, Cell.

[4]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[5]  D. Sabatini,et al.  Nutrient-sensing mechanisms and pathways , 2015, Nature.

[6]  D. Wirth,et al.  Dietary restriction protects against experimental cerebral malaria via leptin modulation and T cell mTORC1 suppression , 2014, Nature Communications.

[7]  L. Okell,et al.  Asymptomatic malaria infections: detectability, transmissibility and public health relevance , 2014, Nature Reviews Microbiology.

[8]  R. Kurumbail,et al.  Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. , 2014, Structure.

[9]  T. Seyfried,et al.  Influence of a ketogenic diet, fish-oil, and calorie restriction on plasma metabolites and lipids in C57BL/6J mice , 2014, Nutrition & Metabolism.

[10]  Américo Rodrigues,et al.  Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases , 2014, Front. Plant Sci..

[11]  J. Thevelein,et al.  Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae , 2014, FEMS microbiology reviews.

[12]  David Carling,et al.  Structural basis of AMPK regulation by small molecule activators , 2013, Nature Communications.

[13]  A. Ivens,et al.  Genome wide dissection of the quorum sensing signaling pathway in Trypanosoma brucei , 2013, Nature.

[14]  R. Weindruch,et al.  Transcriptomics and Metabonomics Identify Essential Metabolic Signatures in Calorie Restriction (CR) Regulation across Multiple Mouse Strains , 2013, Metabolites.

[15]  Cole Trapnell,et al.  TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.

[16]  M. Mann,et al.  Proteomic and Genetic Analyses Demonstrate that Plasmodium berghei Blood Stages Export a Large and Diverse Repertoire of Proteins , 2012, Molecular & Cellular Proteomics.

[17]  M. Llinás,et al.  Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state , 2012, Proceedings of the National Academy of Sciences.

[18]  D. Hardie,et al.  AMP-activated protein kinase: a target for drugs both ancient and modern , 2012, Chemistry & biology.

[19]  G. Barton,et al.  The kinomes of apicomplexan parasites. , 2012, Microbes and infection.

[20]  M. Llinás,et al.  New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community , 2012, Malaria Journal.

[21]  B. Kemp,et al.  The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase , 2012, Science.

[22]  Davis J. McCarthy,et al.  Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation , 2012, Nucleic acids research.

[23]  Yang Liu,et al.  Interaction of SNF1 Protein Kinase with Its Activating Kinase Sak1 , 2011, Eukaryotic Cell.

[24]  S. Teegarden,et al.  Caloric Restriction Experience Reprograms Stress and Orexigenic Pathways and Promotes Binge Eating , 2010, The Journal of Neuroscience.

[25]  Alex Bateman,et al.  The Systematic Functional Analysis of Plasmodium Protein Kinases Identifies Essential Regulators of Mosquito Transmission , 2010, Cell host & microbe.

[26]  C. Howe,et al.  Evolution of the TSC1/TSC2-TOR Signaling Pathway , 2010, Science Signaling.

[27]  L. Partridge,et al.  Extending Healthy Life Span—From Yeast to Humans , 2010, Science.

[28]  Davis J. McCarthy,et al.  edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..

[29]  D. Conway,et al.  Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture , 2009, Proceedings of the National Academy of Sciences.

[30]  A. Sicard,et al.  Disruption of the PfPK7 Gene Impairs Schizogony and Sporogony in the Human Malaria Parasite Plasmodium falciparum , 2007, Eukaryotic Cell.

[31]  Ivo Que,et al.  Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Klein,et al.  Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[33]  D. Carling,et al.  The regulation of AMP-activated protein kinase by phosphorylation. , 2000, The Biochemical journal.

[34]  Stefan Hohmann,et al.  Yeast Stress Responses , 1997, Topics in Current Genetics.

[35]  P. Ambroise‐Thomas,et al.  PfKIN, an SNF1 type protein kinase of Plasmodium falciparum predominantly expressed in gametocytes. , 1996, Molecular and biochemical parasitology.

[36]  N. Hunt,et al.  Amelioration of murine cerebral malaria by dietary restriction , 1993, Parasitology.

[37]  M. Murray,et al.  REFEEDING-MALARIA AND HYPERFERRÆMIA , 1975, The Lancet.

[38]  J. Huxley.  The second biological revolution. , 1946, Lancet.

[39]  Robert H Schiestl,et al.  Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method , 2007, Nature Protocols.

[40]  C. Janse,et al.  High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite Plasmodium berghei , 2006, Nature Protocols.