The literature and market survey reveal that so far there is no preparation of niacin in the form of effervescent tablets (ET) and it is still available in the market as only a conventional tablet. Even this conventional tablet is prepared hardly by a handful of pharmaceuticals. The present study was aimed to formulate the niacin in the form of ET dosage form as an alternative to the available marketed few conventional tablets. ET was made up of effervescent granules (EG). EG are prepared by wet granulation method with non-reactive liquids using PVP as a binder with concentration ratios of 1: 2: 4. As the concentration of PVP is increased, the dissolution profile of niacin was decreased. The formulation F8 containing citric acid, tartaric acid and sodium bicarbonate in the ratio of 1:1:1 was considered to be the best formulation. All the prepared EG and ET are evaluated for the official tests and found to be within limits. Invitro dissolution studies of formulation F8 shows good release by about 95.2% in 3.30 hours. All prepared formulations are slightly acidic (pH 4.0 to 4.2) to augment the taste of the solution. IR Spectra of formulation F8 shows, there is no interaction between niacin and excipients used. And the formulation F8 was most stable at temperature 25oC to 40oC. It conclude that, niacin can prepared in the form of “pleasantly flavored effervescent drink” of ET by compressing EG, which is prepared by wet granulation method with non-reactive liquids.