Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling
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A. Brunner | Xiaoke Yin | M. Mayr | Aikaterini S. Papadopoulou | B. de Strooper | N. Hübner | T. Thum | S. Engelhardt | R. Kumarswamy | S. Werfel | Petros Avramopoulos | D. Ramanujam | Y. Sassi | Laurenz Grüter | Simon Giosele | Dena Esfandyari | B. Laggerbauer | X. Yin | Stanislas Werfel | Andreas-David Brunner
[1] B. Kuster,et al. Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation , 2017, Nucleic acids research.
[2] S. Engelhardt,et al. Viral Vector-Based Targeting of miR-21 in Cardiac Nonmyocyte Cells Reduces Pathologic Remodeling of the Heart , 2016, Molecular therapy : the journal of the American Society of Gene Therapy.
[3] Beverly L. Davidson,et al. Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP , 2016, Nucleic acids research.
[4] Peter Kohl,et al. Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease , 2016, Nature Reviews Drug Discovery.
[5] Jing Zhang,et al. Myocyte-fibroblast communication in cardiac fibrosis and arrhythmias: Mechanisms and model systems. , 2016, Journal of molecular and cellular cardiology.
[6] P. McCrea,et al. Beyond β-catenin: prospects for a larger catenin network in the nucleus , 2015, Nature Reviews Molecular Cell Biology.
[7] Susan M. Schlenner,et al. The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity , 2015, Diabetes.
[8] L. Cascione,et al. Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment , 2015, PloS one.
[9] J. Baron,et al. Evidence That Up-Regulation of MicroRNA-29 Contributes to Postnatal Body Growth Deceleration. , 2015, Molecular endocrinology.
[10] Judith A. Blake,et al. The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease , 2014, Nucleic Acids Res..
[11] René M. Botnar,et al. Role of miR-195 in Aortic Aneurysmal Disease , 2014, Circulation research.
[12] Jun Yu,et al. microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway , 2014, Oncotarget.
[13] Guoying Yu,et al. MicroRNA mimicry blocks pulmonary fibrosis , 2014, EMBO molecular medicine.
[14] Zhonghan Li,et al. Therapeutic targeting of microRNAs: current status and future challenges , 2014, Nature Reviews Drug Discovery.
[15] Arjun Deb. Cell-cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury. , 2014, Cardiovascular research.
[16] A. Didangelos,et al. Extracellular Matrix Secretion by Cardiac Fibroblasts: Role of MicroRNA-29b and MicroRNA-30c , 2013, Circulation research.
[17] Yong Liu,et al. miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation. , 2013, American journal of physiology. Renal physiology.
[18] L. Zentilin,et al. MiR-378 Controls Cardiac Hypertrophy by Combined Repression of Mitogen-Activated Protein Kinase Pathway Factors , 2013, Circulation.
[19] S. Nattel,et al. Role of the Wnt‐Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential , 2013, The Journal of physiology.
[20] A. Hata. Functions of microRNAs in cardiovascular biology and disease. , 2013, Annual review of physiology.
[21] P. Jiang,et al. Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.
[22] J. Mendell,et al. MicroRNAs in Stress Signaling and Human Disease , 2012, Cell.
[23] Merlin C. Thomas,et al. Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis. , 2012, Journal of the American Society of Nephrology : JASN.
[24] Alicia Deng,et al. Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. , 2012, The Journal of clinical investigation.
[25] P. Tsao,et al. miR-29b Participates in Early Aneurysm Development in Marfan Syndrome , 2012, Circulation research.
[26] K. Chowdhury,et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy , 2012, Nature Communications.
[27] Aikaterini S. Papadopoulou,et al. The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor , 2011, Nature Immunology.
[28] M. Vinciguerra,et al. MicroRNA-29 in Aortic Dilation: Implications for Aneurysm Formation , 2011, Circulation research.
[29] J. Qian,et al. miR-29 is a major regulator of genes associated with pulmonary fibrosis. , 2011, American journal of respiratory cell and molecular biology.
[30] Cheuk-Man Yu,et al. TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29. , 2011, Journal of the American Society of Nephrology : JASN.
[31] T. Luedde,et al. Micro‐RNA profiling reveals a role for miR‐29 in human and murine liver fibrosis , 2011, Hepatology.
[32] T. P. Rao,et al. An updated overview on Wnt signaling pathways: a prelude for more. , 2010, Circulation research.
[33] G. Gronowicz,et al. miR-29 Modulates Wnt Signaling in Human Osteoblasts through a Positive Feedback Loop* , 2010, The Journal of Biological Chemistry.
[34] Oliver Distler,et al. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. , 2010, Arthritis and rheumatism.
[35] Hui Zhou,et al. Deep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3′ Trailers , 2010, PloS one.
[36] J. Nerbonne,et al. MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts , 2010, Circulation research.
[37] I. Rigoutsos. New tricks for animal microRNAS: targeting of amino acid coding regions at conserved and nonconserved sites. , 2009, Cancer research.
[38] R. Duisters,et al. MIRNA-133 AND MIRNA-30 REGULATE CONNECTIVE TISSUE GROWTH FACTOR: IMPLICATIONS FOR A ROLE OF MIRNAS IN MYOCARDIAL MATRIX REMODELING , 2013 .
[39] Y. Maejima,et al. Distinct roles of GSK-3α and GSK-3β phosphorylation in the heart under pressure overload , 2008, Proceedings of the National Academy of Sciences.
[40] W. Rottbauer,et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts , 2008, Nature.
[41] C. Burge,et al. Most mammalian mRNAs are conserved targets of microRNAs. , 2008, Genome research.
[42] Jeffrey E. Thatcher,et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis , 2008, Proceedings of the National Academy of Sciences.
[43] S. Bailey,et al. Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. , 2007, American journal of physiology. Heart and circulatory physiology.
[44] C. Croce,et al. MicroRNA-133 controls cardiac hypertrophy , 2007, Nature Medicine.
[45] Xiaoxia Qi,et al. Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA , 2007, Science.
[46] E. Wentzel,et al. A Hexanucleotide Element Directs MicroRNA Nuclear Import , 2007, Science.
[47] Ajamete Kaykas,et al. Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements , 2003, Current Biology.
[48] E. Olson,et al. Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[49] Chris Albanese,et al. Negative regulation of the Wnt–β‐catenin pathway by the transcriptional repressor HBP1 , 2001, The EMBO journal.
[50] I. Saito,et al. Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination. , 1998, Gene.
[51] F. Alt,et al. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[52] D. Solter,et al. Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells , 1993, Transgenic Research.
[53] J. Ross,et al. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[54] T. Friedmann. An ASGCT Perspective on the National Academies Genome Editing Summit. , 2016, Molecular therapy : the journal of the American Society of Gene Therapy.
[55] Koen Van Laer,et al. Current status and future challenges , 2015 .
[56] Elisa Izaurralde,et al. NON-CODING RNA Towards a molecular understanding of microRNA-mediated gene silencing , 2015 .
[57] T. Thum,et al. A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. , 2012, Journal of molecular and cellular cardiology.
[58] E. Olson,et al. Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. , 2002, Proceedings of the National Academy of Sciences of the United States of America.