Local anesthesia; Toxicity; Lipid emulsion; Prevention; Treatment.

[1]  B. Finucane,et al.  Local anesthetic systemic toxicity , 2010, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[2]  J. Neal,et al.  ASRA Practice Advisory on Local Anesthetic Systemic Toxicity , 2009, Regional Anesthesia & Pain Medicine.

[3]  T. Martin,et al.  Use of Intralipid in an infant with impending cardiovascular collapse due to local anesthetic toxicity , 2009, Journal of Anesthesia.

[4]  G. Fanelli,et al.  Pharmacology, toxicology, and clinical use of new long acting local anesthetics, ropivacaine and levobupivacaine. , 2008, Acta bio-medica : Atenei Parmensis.

[5]  J. Gerancher,et al.  Early Intralipid Therapy May Have Prevented Bupivacaine‐Associated Cardiac Arrest , 2008, Regional anesthesia and pain medicine.

[6]  N. Bedforth,et al.  Levobupivacaine‐induced seizures and cardiovascular collapse treated with Intralipid® , 2007, Anaesthesia.

[7]  David.L Brown,et al.  Local Anesthetic Toxicity , 2007 .

[8]  S. Stehr,et al.  Successful resuscitation of a patient with ropivacaine‐induced asystole after axillary plexus block using lipid infusion * , 2006, Anaesthesia.

[9]  J. Eisenkraft,et al.  Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. , 2006, Anesthesiology.

[10]  D. Feinstein,et al.  Lipid Infusion Accelerates Removal of Bupivacaine and Recovery From Bupivacaine Toxicity in the Isolated Rat Heart , 2005, Regional Anesthesia & Pain Medicine.

[11]  P. Neuvonen,et al.  Pharmacokinetics of Ropivacaine in Uremic and Nonuremic Patients After Axillary Brachial Plexus Block , 2003, Anesthesia and analgesia.

[12]  M. Mulroy Systemic Toxicity and Cardiotoxicity From Local Anesthetics: Incidence and Preventive Measures , 2002, Regional Anesthesia & Pain Medicine.

[13]  R. Gristwood Cardiac and CNS Toxicity of Levobupivacaine , 2002 .

[14]  A. Borgeat,et al.  From cocaine to ropivacaine: the history of local anesthetic drugs. , 2001, Current topics in medicinal chemistry.

[15]  T. Nelson,et al.  Is Comparative Cardiotoxicity of S(−) and R(+) Bupivacaine Related to Enantiomer-Selective Inhibition of L-Type Ca2+ Channels? , 2001, Anesthesia and analgesia.

[16]  G. Weinberg,et al.  Pretreatment or Resuscitation with a Lipid Infusion Shifts the Dose‐Response to Bupivacaine‐induced Asystole in Rats , 1998, Anesthesiology.

[17]  B. Graf,et al.  Stereospecific Effect of Bupivacaine Isomers on Atrioventricular Conduction in the Isolated Perfused Guinea Pig Heart , 1997, Anesthesiology.

[18]  K. Samii,et al.  Myocardial uptake of bupivacaine: II. Pharmacokinetics and pharmacodynamics of bupivacaine enantiomers in the isolated perfused rabbit heart. , 1993, Anesthesia and analgesia.

[19]  B. Covino,et al.  Effect of progesterone on the cardiac electrophysiologic alterations produced by ropivacaine and bupivacaine. , 1992, Anesthesiology.

[20]  F. Walker,et al.  Pregnancy Increases Median Nerve Susceptibility to Lidocaine , 1990 .

[21]  R. Lindberg,et al.  EXTRADURAL ADMINISTRATION OF BUPIVACAINE: PHARMACOKINETICS AND METABOLISM IN PREGNANT AND NON-PREGNANT WOMEN , 1990 .

[22]  D. Denson,et al.  Alpha1‐acid glycoprotein and albumin in human serum bupivacaine binding , 1984 .

[23]  A. Barson,et al.  Fat embolism in infancy after intravenous fat infusions. , 1978, Archives of disease in childhood.

[24]  M. H. Alper Toxicity of local anesthetics. , 1976, The New England journal of medicine.

[25]  D. Moore,et al.  Oxygen: the antidote for systemic toxic reactions from local anesthetic drugs. , 1960, JAMA.

[26]  P. E. Ireland,et al.  The clinical and experimental comparison of cocaine and pontocaine as topical anesthetics in otolaryngological practice , 1951, The Laryngoscope.