Salivary changes, oral symptoms, and oral health-related quality of life in patients with neuromuscular diseases

y el test el nivel de de Resultados: la esclero-sis fue la enfermedad de base más prevalente (50 %). El promedio del salivar en reposo fue de ± con un hiperflujo del % de los pacientes e hiposalivación del 3.3 %. El promedio del pH salivar fue 6.47 ± 0.57. Los síntomas orales más frecuentes fueron disfagia (56.7 %) y xerostomía (43.3 %). El promedio del Oral Health Impact Profile -14 fue de 5.54 ± 4.93 y el 90 % de los pacientes presentó algún impacto de las condiciones bucales en su calidad de vida. Los síntomas de disfagia, xerostomía, ardor bucal y sialorrea presentaron una asociación estadísticamente significante ( p <0.05) con la calidad de vida relacionada con la salud bucal. Las dimensiones del Oral Health Impact Profile -14 que presentaron mayores porcentajes fueron la inhabilidad psicológica (14.5 %) y la limita-ción funcional (13.5 %). Conclusión: la mayoría de los pacientes presentó una disfunción de las glándulas salivares, y la presencia de síntomas bucales influenció negativamente la percepción de la calidad de vida de los individuos con enfermedades neuromusculares. Palabras enfermedades hospitala-ria Abstract Introduction: The aim of this study was to evaluate the salivary flow, the presence of oral symptoms, and the oral health-related quality of life perceptions among individuals with neuromuscular diseases. Materials and Methods: It is a cross-sectional study, with 30 individuals with neuromuscular diseases treated at a neurorehabilitation clinic of a Brazilian university hospital from October to December 2017. Anamnesis, assessment of resting salivary flow, and measurement of salivary pH were performed. The instrument Oral Health Impact Profile-14 was used to evaluate the oral health-related quality of life. Data were analyzed using descriptive analysis and chi-square test, using a 5 % significance level (p <0.05). Results: Amyotrophic Lateral Sclerosis was the most common disease in the group (50 %). The mean resting salivary flow was 0.44 ml/min, where it was found 43.3 % of high salivary flow and 3.3 % of hypo-salivation. The mean salivary pH found was 6.47 ± 0.57, where 56.6 % of the patients had neutral pH and 40 % low pH. The most prevalent oral symptoms were dysphagia (56.7 %) and xerostomia (43.3 %). The mean Oral Health Impact Profile-14 was 5.54 ± 4.93, with 90 % of patients presenting some impact of oral conditions on quality of life. A statistically significant association (p <0.05) between the quality of life and symptoms of dysphagia, xerostomia, oral burning, and sialorrhea was found. The Oral Health Impact Profile-14 dimensions with the highest percentages were psychological inability (14.5 %) and functional limitation (13.5 %). Conclusion: The majority of patients presented salivary gland dysfunction with high salivary flows. The presence of oral symptoms negatively influenced the individual’s quality of life perceptions of individuals with neuromuscular diseases.

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