Schizotypal dimensions in normals and schizophrenic patients: a comparison with other clinical samples

Schizotypy is usually referred to as a "liability" to schizophrenia, but it could also be more generally referred to as nonspecific "psychosis-proneness". This study examined the structure of schizotypy in a normal sample and in a sample of schizophrenics through the administration of the Schizotypal Personality Questionnaire (SPQ). Within a "fully dimensional" approach to psychiatric disorders, this study also compared SPQ scores in clinical samples of subjects with bipolar, unipolar and obsessive-compulsive (OCD) disorders. The results suggested that the disorganized three-factor model, Cognitive-Perceptual, Interpersonal Deficits and Disorganization, underlies individual differences across samples of normal and schizophrenic patients. Furthermore, the SPQ measures discriminated schizophrenia and bipolars from major depression but not from OCD.

[1]  L. J. Chapman,et al.  Putatively psychosis-prone subjects 10 years later. , 1994, Journal of abnormal psychology.

[2]  G. Claridge,et al.  Fully and quasi-dimensional constructions of schizotypy , 1995 .

[3]  P. Venables,et al.  The structure of schizotypy, its relation to subdiagnoses of schizophrenia and to sex and age. , 1994, The British journal of clinical psychology.

[4]  M. Karayiorgou,et al.  Evidence of a schizotypy subtype in OCD. , 2000, Journal of psychiatric research.

[5]  A. Raine The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. , 1991, Schizophrenia bulletin.

[6]  J. Hewitt,et al.  The factor structure of schizotypy in a normal population , 1989 .

[7]  A. Rossi,et al.  Pattern of Comorbidity Among Anxious and Odd Personality Disorders: The Case of Obsessive-Compulsive Personality Disorder , 2000, CNS Spectrums.

[8]  M. Battaglia,et al.  Latent class analysis of DSM-IV schizotypal personality disorder criteria in psychiatric patients. , 2001, Schizophrenia bulletin.

[9]  M. Lenzenweger,et al.  Schizotypal Personality: Tracking the taxon: on the latent structure and base rate of schizotypy , 1995 .

[10]  S. Mednick,et al.  Three-factor model of schizotypal personality: invariance across culture, gender, religious affiliation, family adversity, and psychopathology. , 2000, Schizophrenia bulletin.

[11]  A. Raine,et al.  Cognitive-perceptual, interpersonal, and disorganized features of schizotypal personality. , 1994, Schizophrenia bulletin.

[12]  van den Robert Bosch,et al.  The multidimensionality of schizotypy. , 1995, Schizophrenia bulletin.

[13]  H. Hoijtink,et al.  The multidimensionality of self-report schizotypy in a psychiatric population: an analysis using multidimensional Rasch models. , 2000, Schizophrenia bulletin.

[14]  G. A. Miller,et al.  Comparing borderline definitions: DSM-III borderline and schizotypal personality disorders. , 1989, Journal of abnormal psychology.

[15]  S. Pallanti The Anxiety-Psychosis Spectrum , 2000, CNS Spectrums.

[16]  Paul E. Meehl,et al.  Toward an Integrated Theory of Schizotaxia, Schizotypy, and Schizophrenia , 1990 .

[17]  A. McCutcheon,et al.  Latent Class Analysis , 2021, Encyclopedia of Autism Spectrum Disorders.

[18]  M. Battaglia,et al.  Schizotypal disorder: at the crossroads of genetics and nosology , 1996, Acta psychiatrica Scandinavica.

[19]  R. Bentall,et al.  The multidimensional nature of schizotypal traits: a factor analytic study with normal subjects. , 1989, The British journal of clinical psychology.

[20]  R. Bentall,et al.  The factor structure of "schizotypal' traits: a large replication study. , 1996, The British journal of clinical psychology.

[21]  Gordon Claridge,et al.  Theoretical background and issues , 1997 .

[22]  A. Gorman,et al.  The structure of schizotypy: A pilot multitrait twin study , 1991, Psychiatry Research.

[23]  F. Macciardi,et al.  The structure of DSM-III-R schizotypal personality disorder diagnosed by direct interviews. , 1997, Schizophrenia bulletin.

[24]  Philip D. Harvey,et al.  The factor structure of schizotypal symptoms in a clinical population. , 1996, Schizophrenia bulletin.

[25]  Philip D. Harvey,et al.  Schizotypal symptoms in the relatives of schizophrenia patients: an empirical analysis of the factor structure. , 2000, Schizophrenia bulletin.

[26]  T. Crow,et al.  A continuum of psychosis, one human gene, and not much else — the case for homogeneity , 1995, Schizophrenia Research.

[27]  M. Tsuang Schizophrenia: genes and environment , 2000, Biological Psychiatry.

[28]  K. Kendler,et al.  The structure of psychosis: latent class analysis of probands from the Roscommon Family Study. , 1998, Archives of general psychiatry.

[29]  P. Venables Schizotypal Personality: Schizotypal status as a developmental stage in studies of risk for schizophrenia , 1995 .

[30]  P. Venables,et al.  The content and structure of schizotypy: a study using confirmatory factor analysis. , 2000, Schizophrenia bulletin.

[31]  K. Kendler,et al.  Schizotypal symptoms and signs in the Roscommon Family Study. Their factor structure and familial relationship with psychotic and affective disorders. , 1995, Archives of general psychiatry.