In vivo distribution of carotenoids in different anatomical locations of human skin: comparative assessment with two different Raman spectroscopy methods

Background:  The cutaneous antioxidants form an efficient protection system against the destructive potential of free radicals, produced by environmental factors, such as UV‐sun irradiation, hazardous substances and lifestyle habits. Most of the antioxidants cannot be produced by the human organism. Thus, they have to be incorporated by food and beverages.

[1]  P. Wardman,et al.  Sunscreens inadequately protect against ultraviolet-A-induced free radicals in skin: implications for skin aging and melanoma? , 2003, The Journal of investigative dermatology.

[2]  C. Mcguigan,et al.  Topical Delivery of Retinyl Ascorbate Co-Drug , 2004, Skin Pharmacology and Physiology.

[3]  Maxim E. Darvin,et al.  In vivo Raman spectroscopic analysis of the influence of IR radiation on the carotenoid antioxidant substances beta-carotene and lycopene in the human skin. Formation of free radicals , 2007 .

[4]  D. Costantini,et al.  Effects of carotenoid supplementation on colour expression, oxidative stress and body mass in rehabilitated captive adult kestrels (Falco tinnunculus) , 2007, Journal of Comparative Physiology B.

[5]  C. Mcguigan,et al.  Topical Delivery of Retinyl Ascorbate Co-Drug , 2004, Skin Pharmacology and Physiology.

[6]  U. Blume-Peytavi,et al.  Stratum corneum maturation. A review of neonatal skin function. , 2004, Skin pharmacology and physiology.

[7]  R. Guy,et al.  Assessment of the “Skin Reservoir” of Urea by Confocal Raman Microspectroscopy and Reverse Iontophoresis in vivo , 2007, Pharmaceutical Research.

[8]  V. Ruocco,et al.  Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A Double-Blind, Placebo-Controlled Study , 2007, Skin Pharmacology and Physiology.

[9]  E. Berardesca,et al.  Impact of anatomical location on barrier recovery, surface pH and stratum corneum hydration after acute barrier disruption , 2002, The British journal of dermatology.

[10]  Heike Richter,et al.  Application of optical non‐invasive methods in skin physiology: a comparison of laser scanning microscopy and optical coherent tomography with histological analysis , 2007, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[11]  Paul L Carson,et al.  Imaging of joints with laser-based photoacoustic tomography: an animal study. , 2006, Medical physics.

[12]  L. Miséry.  How the skin reacts to environmental factors , 2007, Journal of the European Academy of Dermatology and Venereology : JEADV.

[13]  V. Calabrese,et al.  Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology. , 2000, International journal of tissue reactions.

[14]  Don McNaughton,et al.  Resonance Raman spectroscopy of red blood cells using near-infrared laser excitation , 2007, Analytical and bioanalytical chemistry.

[15]  J. Thiele,et al.  DieTalgdrüse als Transporter für Vitamin E , 2006, Der Hautarzt.

[16]  J. Levy,et al.  Lycopene in serum, skin and adipose tissues after tomato-oleoresin supplementation in patients undergoing haemorrhoidectomy or peri-anal fistulotomy , 2003, British Journal of Nutrition.

[17]  C. Heard,et al.  Topical delivery of retinyl ascorbate co-drug. 1. Synthesis, penetration into and permeation across human skin. , 2004, International journal of pharmaceutics.

[18]  Maxim E. Darvin,et al.  Non-invasive in vivo detection of the carotenoid antioxidant substance lycopene in the human skin using the resonance Raman spectroscopy , 2006 .

[19]  Ulrike Blume-Peytavi,et al.  One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors. , 2008, Journal of biomedical optics.

[20]  Dae-Duk Kim,et al.  Evidence supporting antioxidant action of adipose-derived stem cells: protection of human dermal fibroblasts from oxidative stress. , 2008, Journal of dermatological science.

[21]  Vrushali R. Korde,et al.  Using optical coherence tomography to evaluate skin sun damage and precancer , 2007, Lasers in surgery and medicine.

[22]  U. Blume-Peytavi,et al.  Stratum Corneum Maturation , 2004, Skin Pharmacology and Physiology.

[23]  J. Lademann,et al.  Application of in-vivo laser scanning microscopy for evaluation of barrier creams , 2007 .

[24]  T. Herrling,et al.  Integrated Sun Protection Factor: A New Sun Protection Factor Based on Free Radicals Generated by UV Irradiation , 2004, Skin Pharmacology and Physiology.

[25]  J. Lademann,et al.  Effect of Supplemented and Topically Applied Antioxidant Substances on Human Tissue , 2006, Skin Pharmacology and Physiology.

[26]  H. Bruining,et al.  In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles. , 2001, The Journal of investigative dermatology.

[27]  Gerwin J. Puppels,et al.  Monitoring the Penetration Enhancer Dimethyl Sulfoxide in Human Stratum Corneum in Vivo by Confocal Raman Spectroscopy , 2002, Pharmaceutical Research.