Enhancing Surveillance and Diagnostics in Anthrax-Endemic Countries

Naturally occurring anthrax disproportionately affects the health and economic welfare of poor, rural communities in anthrax-endemic countries. However, many of these countries have limited anthrax prevention and control programs. Effective prevention of anthrax outbreaks among humans is accomplished through routine livestock vaccination programs and prompt response to animal outbreaks. The Centers for Disease Control and Prevention uses a 2-phase framework when providing technical assistance to partners in anthrax-endemic countries. The first phase assesses and identifies areas for improvement in existing human and animal surveillance, laboratory diagnostics, and outbreak response. The second phase provides steps to implement improvements to these areas. We describe examples of implementing this framework in anthrax-endemic countries. These activities are at varying stages of completion; however, the public health impact of these initiatives has been encouraging. The anthrax framework can be extended to other zoonotic diseases to build on these efforts, improve human and animal health, and enhance global health security.

[1]  S. Salyer,et al.  Prioritizing Zoonoses for Global Health Capacity Building—Themes from One Health Zoonotic Disease Workshops in 7 Countries, 2014–2016 , 2017, Emerging infectious diseases.

[2]  J. Blackburn,et al.  Modeling the environmental suitability of anthrax in Ghana and estimating populations at risk: Implications for vaccination and control , 2017, PLoS neglected tropical diseases.

[3]  ArthurRay,et al.  Global Health Security: Building Capacities for Early Event Detection, Epidemiologic Workforce, and Laboratory Response. , 2016, Health security.

[4]  J. Rushton,et al.  Economic Assessment of Zoonoses Surveillance in a ‘One Health’ Context: A Conceptual Framework , 2016, Zoonoses and public health.

[5]  Jennifer B Nuzzo,et al.  Public Health Surveillance: At the Core of the Global Health Security Agenda. , 2016, Health security.

[6]  A. Mounts,et al.  Global Health Security: Building Capacities for Early Event Detection, Epidemiologic Workforce, and Laboratory Response. , 2016, Health security.

[7]  Ahmed El Idrissi Sean Shadomy,et al.  Anthrax outbreaks : a warning for improved prevention , control and heightened awareness empres watch , 2016 .

[8]  H. Margolis,et al.  Underrecognition of Dengue during 2013 Epidemic in Luanda, Angola , 2015, Emerging infectious diseases.

[9]  Nicholas D. Preston,et al.  Drivers of Emerging Infectious Disease Events as a Framework for Digital Detection , 2015, Emerging infectious diseases.

[10]  S. Shadomy,et al.  Human anthrax outbreak associated with livestock exposure: Georgia, 2012 , 2015, Epidemiology and Infection.

[11]  A. Goel Anthrax: A disease of biowarfare and public health importance. , 2015, World journal of clinical cases.

[12]  F. Misgie,et al.  A Review on Anthrax and its Public Health and Economic Importance , 2015 .

[13]  C. Rubin,et al.  Prioritizing Zoonoses: A Proposed One Health Tool for Collaborative Decision-Making , 2014, PloS one.

[14]  J. Frean,et al.  Anthrax as an example of the One Health concept. , 2014, Revue scientifique et technique.

[15]  X. Cui,et al.  An overview of anthrax infection including the recently identified form of disease in injection drug users , 2012, Intensive Care Medicine.

[16]  A. Hoffmaster,et al.  Anthrax outbreaks in Bangladesh, 2009-2010. , 2012, The American journal of tropical medicine and hygiene.

[17]  A. Hoffmaster,et al.  Lethal Factor Toxemia and Anti-Protective Antigen Antibody Activity in Naturally Acquired Cutaneous Anthrax , 2011, The Journal of infectious diseases.

[18]  A. Fasanella,et al.  Anthrax undervalued zoonosis. , 2010, Veterinary microbiology.

[19]  M. Hugh-jones,et al.  The ecology of Bacillus anthracis. , 2009, Molecular aspects of medicine.

[20]  Theresa L. Smith,et al.  Zoonosis update. Anthrax. , 2008, Journal of the American Veterinary Medical Association.

[21]  M. Peiris,et al.  International Health Regulations (2005) , 2005, The Lancet.

[22]  A. Kaufmann,et al.  Anthrax in Europe: its epidemiology, clinical characteristics, and role in bioterrorism. , 2002, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[23]  C. Dolea,et al.  World Health Organization , 1949, International Organization.