University of Groningen NFE 2 L 2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease

[1]  Christian Gieger,et al.  Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function , 2011, Nature Genetics.

[2]  E. Noguchi,et al.  An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study , 2011, BMC Medical Genetics.

[3]  David M. Evans,et al.  A Comprehensive Evaluation of Potential Lung Function Associated Genes in the SpiroMeta General Population Sample , 2011, PloS one.

[4]  Edwin K Silverman,et al.  Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. , 2011, American journal of respiratory and critical care medicine.

[5]  Inês Barroso,et al.  Genome-wide association study identifies five loci associated with lung function , 2010, Nature Genetics.

[6]  Christoph Lange,et al.  Variants in FAM13A are associated with chronic obstructive pulmonary disease , 2010, Nature Genetics.

[7]  A. Hofman,et al.  Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function , 2010, Nature Genetics.

[8]  D. Postma,et al.  Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. , 2009, American journal of respiratory and critical care medicine.

[9]  D. Postma,et al.  Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population , 2009, Respiratory research.

[10]  L. Z. Akhmadishina,et al.  Polymorphism of the genes for antioxidant defense enzymes and their association with the development of chronic obstructive pulmonary disease in the population of Bashkortostan , 2009, Russian Journal of Genetics.

[11]  K. Shianna,et al.  A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci , 2009, PLoS genetics.

[12]  Scott T. Weiss,et al.  A Genome-Wide Association Study of Pulmonary Function Measures in the Framingham Heart Study , 2009, PLoS genetics.

[13]  Kim W. Carter,et al.  SimHap GUI: An intuitive graphical user interface for genetic association analysis , 2008, BMC Bioinformatics.

[14]  Masayuki Yamamoto,et al.  The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds , 2008, Molecular and Cellular Biology.

[15]  Deepti Malhotra,et al.  Decline in Nrf2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, Dj-1 , 2022 .

[16]  Cleo C. van Diemen,et al.  Lung function loss, smoking, vitamin C intake, and polymorphisms of the glutamate-cysteine ligase genes. , 2008, American journal of respiratory and critical care medicine.

[17]  D. Postma,et al.  Heme oxygenase 1 variations and lung function decline in smokers: proof of replication , 2008, Journal of Medical Genetics.

[18]  R. Tkacova,et al.  Glutathione S-transferase and microsomal epoxide hydrolase gene polymorphisms and risk of chronic obstructive pulmonary disease in Slovak population. , 2008, Croatian medical journal.

[19]  Frank Dudbridge,et al.  Likelihood-Based Association Analysis for Nuclear Families and Unrelated Subjects with Missing Genotype Data , 2008, Human Heredity.

[20]  S. Hong,et al.  The role of Bach2 in nucleic acid-triggered antiviral innate immune responses. , 2008, Biochemical and biophysical research communications.

[21]  J. Maurer Genetic Association Analysis of Functional Impairment in Chronic Obstructive Pulmonary Disease , 2008 .

[22]  Santiago Rodríguez,et al.  Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX' , 2007, BMC Bioinformatics.

[23]  N. Anthonisen,et al.  Polymorphisms of interleukin-10 and its receptor and lung function in COPD , 2007, European Respiratory Journal.

[24]  M. Imboden,et al.  Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study , 2007, Respiratory research.

[25]  Cleo C. van Diemen,et al.  A Disintegrin and Metalloprotease 33 polymorphisms and lung function decline in the general population , 2006, European Respiratory Review.

[26]  T. Mak,et al.  DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2 , 2006, Proceedings of the National Academy of Sciences.

[27]  A. Kikuchi,et al.  Heme oxygenase-1 gene promoter polymorphism and decline in lung function in Japanese men , 2006, Thorax.

[28]  P. Demoly,et al.  Association of lung function decline with the heme oxygenase-1 gene promoter microsatellite polymorphism in a general population sample. Results from the European Community Respiratory Health Survey (ECRHS), France , 2006, Journal of Medical Genetics.

[29]  A. Kong,et al.  Regulation of Nrf2 transactivation domain activity by p160 RAC3/SRC3 and other nuclear co-regulators. , 2006, Journal of biochemistry and molecular biology.

[30]  Masayuki Yamamoto,et al.  Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. , 2006, The Journal of clinical investigation.

[31]  P. Valentin-Weigand,et al.  Mycobacterium paratuberculosis, Mycobacterium smegmatis, and lipopolysaccharide induce different transcriptional and post‐transcriptional regulation of the IRG1 gene in murine macrophages , 2006, Journal of leukocyte biology.

[32]  Daniel C Liebler,et al.  Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation* , 2005, Journal of Biological Chemistry.

[33]  J. Li,et al.  Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix , 2005, Heredity.

[34]  John M Pezzuto,et al.  Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[35]  N. Laird,et al.  Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. , 2005, American journal of respiratory cell and molecular biology.

[36]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[37]  Irina Petrache,et al.  Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. , 2004, The Journal of clinical investigation.

[38]  P. Paré,et al.  Glutathione S-transferase variants and their interaction with smoking on lung function. , 2004, American journal of respiratory and critical care medicine.

[39]  Masayuki Yamamoto,et al.  Identification of polymorphisms in the promoter region of the human NRF2 gene. , 2004, Biochemical and biophysical research communications.

[40]  P. Yang,et al.  Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD , 2004, European Respiratory Journal.

[41]  Ralf Janknecht,et al.  Concerted Activation of ETS Protein ER81 by p160 Coactivators, the Acetyltransferase p300 and the Receptor Tyrosine Kinase HER2/Neu* , 2004, Journal of Biological Chemistry.

[42]  D. Nyholt A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. , 2004, American journal of human genetics.

[43]  N. Copeland,et al.  Cloning and analysis of gene regulation of a novel LPS-inducible cDNA , 1995, Immunogenetics.

[44]  C. Carlson,et al.  Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. , 2004, American journal of human genetics.

[45]  J. D. Engel,et al.  Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation , 2003, Nature Genetics.

[46]  R. Cole,et al.  Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[47]  C. Yoo,et al.  Lack of Association Between Glutathione S-transferase P1 Polymorphism and COPD in Koreans , 2002, Lung.

[48]  E. Silverman,et al.  Chronic obstructive pulmonary disease • 1: Susceptibility factors for COPD the genotype–environment interaction , 2002, Thorax.

[49]  P. Paré,et al.  Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers. , 2002, American journal of respiratory and critical care medicine.

[50]  N. Wareham,et al.  Siblings of Patients with Severe Chronic Obstructive Pulmonary Disease Have a Significant Risk of Airflow Obstruction , 2002 .

[51]  E. Broadfield,et al.  Prospective study of diet and decline in lung function in a general population. , 2002, American journal of respiratory and critical care medicine.

[52]  J. Qin,et al.  Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. , 2002, Molecular and cellular biology.

[53]  N. Kudo,et al.  Oxidative Stress Abolishes Leptomycin B-sensitive Nuclear Export of Transcription Repressor Bach2 That Counteracts Activation of Maf Recognition Element* , 2000, The Journal of Biological Chemistry.

[54]  P. Cassano,et al.  Antioxidant nutrients and pulmonary function: the Third National Health and Nutrition Examination Survey (NHANES III). , 2000, American journal of epidemiology.

[55]  W. MacNee,et al.  Oxidants/antioxidants and COPD. , 2000, Chest.

[56]  J. Yim,et al.  Genetic susceptibility to chronic obstructive pulmonary disease in Koreans: combined analysis of polymorphic genotypes for microsomal epoxide hydrolase and glutathione S-transferase M1 and T1 , 2000, Thorax.

[57]  S. Shibahara,et al.  Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. , 2000, American journal of human genetics.

[58]  R. Lanz,et al.  RAC-3 is a NF-kappa B coactivator. , 2000, FEBS letters.

[59]  Han-Jong Kim,et al.  Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53. , 1999, Molecular endocrinology.

[60]  J. D. Engel,et al.  Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. , 1999, Genes & development.

[61]  L. Madisen,et al.  Identification of Bach2 as a B‐cell‐specific partner for small Maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer , 1998, The EMBO journal.

[62]  H. Schünemann,et al.  Oxidative stress and lung function. , 1997, American journal of epidemiology.

[63]  R. Evans,et al.  Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300 , 1997, Cell.

[64]  W. Bailey,et al.  Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. , 1995, JAMA.

[65]  A. Buist,et al.  Spirometry in the Lung Health Study. 1. Methods and quality control. , 1991, The American review of respiratory disease.

[66]  F. Speizer,et al.  Assessment of genetic and nongenetic influences on pulmonary function. A twin study. , 2015, The American review of respiratory disease.

[67]  M Terrin,et al.  Reference spirometric values using techniques and equipment that meet ATS recommendations. , 2015, The American review of respiratory disease.

[68]  R. Peto,et al.  The natural history of chronic airflow obstruction. , 1977, British medical journal.