Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
暂无分享,去创建一个
David R. Liu | Gregory A. Newby | Luke W. Koblan | Jordan L. Doman | Luke W Koblan | Christopher Wilson | Jonathan M. Levy | Tristan Tay | J. P. Maianti | Aditya Raguram
[1] E. Myers,et al. Basic local alignment search tool. , 1990, Journal of molecular biology.
[2] A. R. Wagner. Molecular Biology and Evolution , 2001 .
[3] G. Raymond,et al. MPDU1 mutations underlie a novel human congenital disorder of glycosylation, designated type If. , 2001, The Journal of clinical investigation.
[4] F. Drabløs,et al. Uracil in DNA – occurrence, consequences and repair , 2002, Oncogene.
[5] Cathy H. Wu,et al. UniProt: the Universal Protein knowledgebase , 2004, Nucleic Acids Res..
[6] Ziheng Yang. PAML 4: phylogenetic analysis by maximum likelihood. , 2007, Molecular biology and evolution.
[7] Internation Journal of laboratory Hematology. , 2008 .
[8] D. G. Gibson,et al. Enzymatic assembly of DNA molecules up to several hundred kilobases , 2009, Nature Methods.
[9] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[10] H. Park,et al. High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice , 2011, PloS one.
[11] K. Katoh,et al. MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability , 2013, Molecular biology and evolution.
[12] J. A. Gavira,et al. Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases. , 2013, Journal of the American Chemical Society.
[13] M. Harms,et al. Evolutionary biochemistry: revealing the historical and physical causes of protein properties , 2013, Nature Reviews Genetics.
[14] Hollis G. Potter,et al. Author Manuscript , 2013 .
[15] P. Grisanti,et al. Interpreting elevated fetal hemoglobin in pathology and health at the basic laboratory level: new and known γ‐ gene mutations associated with hereditary persistence of fetal hemoglobin , 2014, International journal of laboratory hematology.
[16] C. Woods,et al. Painful and painless channelopathies , 2014, The Lancet Neurology.
[17] A. von Haeseler,et al. IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies , 2014, Molecular biology and evolution.
[18] G. Hong,et al. Nucleic Acids Research , 2015, Nucleic Acids Research.
[19] David R. Liu,et al. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage , 2016, Nature.
[20] David R. Liu,et al. Continuous evolution of B. thuringiensis toxins overcomes insect resistance , 2016, Nature.
[21] Ricardo Villamarín-Salomón,et al. ClinVar: public archive of interpretations of clinically relevant variants , 2015, Nucleic Acids Res..
[22] Lucas C Wheeler,et al. The thermostability and specificity of ancient proteins. , 2016, Current opinion in structural biology.
[23] Edward M. Callaway,et al. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration , 2016, Nature.
[24] Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage , 2017, Nature.
[25] Dan Liu,et al. Correction of β-thalassemia mutant by base editor in human embryos , 2017, Protein & Cell.
[26] Gaelen T. Hess,et al. Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes. , 2017, Molecular cell.
[27] Thomas K. F. Wong,et al. ModelFinder: Fast Model Selection for Accurate Phylogenetic Estimates , 2017, Nature Methods.
[28] Kevin T. Zhao,et al. Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity , 2017, Science Advances.
[29] Guanglei Li,et al. Highly efficient and precise base editing in discarded human tripronuclear embryos , 2017, Protein & Cell.
[30] Kevin T. Zhao,et al. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions , 2017, Nature Biotechnology.
[31] David R. Liu,et al. Evolved Cas9 variants with broad PAM compatibility and high DNA specificity , 2018, Nature.
[32] Eugene Chung,et al. Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy , 2018, Nature Biotechnology.
[33] A. von Haeseler,et al. UFBoot2: Improving the Ultrafast Bootstrap Approximation , 2017, bioRxiv.
[34] The Uniprot Consortium. UniProt: the universal protein knowledgebase , 2018, Nucleic acids research.
[35] J. Coller,et al. Codon optimality, bias and usage in translation and mRNA decay , 2017, Nature Reviews Molecular Cell Biology.
[36] Martha L. Bulyk,et al. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch , 2018, Cell.