Transforming growth factor‐β1 induced alteration of skeletal morphogenesis in vivo

[1]  Thomas A Einhorn,et al.  Fracture healing as a post‐natal developmental process: Molecular, spatial, and temporal aspects of its regulation , 2003, Journal of cellular biochemistry.

[2]  J. Puzas,et al.  A Role for the BMP Antagonist Chordin in Endochondral Ossification , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[3]  D. Dorsa,et al.  Neuronal apoptosis resulting from high doses of the isoflavone genistein: role for calcium and p42/44 mitogen-activated protein kinase. , 2001, The Journal of pharmacology and experimental therapeutics.

[4]  E. Schwarz,et al.  PTHrP expression in chick sternal chondrocytes is regulated by TGF‐β through Smad‐mediated signaling , 2001, Journal of cellular physiology.

[5]  T. Nohno,et al.  Differential response of Shh expression between chick forelimb and hindlimb buds by FGF‐4 , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[6]  R. Serra,et al.  The perichondrium plays an important role in mediating the effects of TGF‐β1 on endochondral bone formation , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[7]  V. Goldberg,et al.  BMP‐2 induction and TGF‐β1 modulation of rat periosteal cell chondrogenesis , 2001 .

[8]  P. Billings,et al.  Authentic Matrix Vesicles Contain Active Metalloproteases (MMP) , 2001, The Journal of Biological Chemistry.

[9]  C. Deng,et al.  TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular Cartilage , 2001, The Journal of cell biology.

[10]  E. Schwarz,et al.  Smad2 and 3 Mediate Transforming Growth Factor-β1-Induced Inhibition of Chondrocyte Maturation* *The work was supported by National Health Services Grant AR-38945 (to R.J.O.) and an Orthopaedic Research Education Foundation Award (to C.M.F.). , 2000, Endocrinology.

[11]  P. Billings,et al.  MMP‐13 is induced during chondrocyte hypertrophy , 2000, Journal of cellular biochemistry.

[12]  M. D'souza,et al.  PTHrP expression in chondrocytes, regulation by TGF-beta, and interactions between epiphyseal and growth plate chondrocytes. , 2000, Experimental cell research.

[13]  D. Hu,et al.  The role of sonic hedgehog in normal and abnormal craniofacial morphogenesis. , 1999, Development.

[14]  P. ten Dijke,et al.  Localization of Smads, the TGF‐β Family Intracellular Signaling Components During Endochondral Ossification , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[15]  T. Yamamoto,et al.  Temporal and spatial expressions of transforming growth factor-betas and their receptors in epiphyseal growth plate. , 1999, International journal of oncology.

[16]  P. Sharpe,et al.  Regulation and role of Sox9 in cartilage formation , 1999, Developmental dynamics : an official publication of the American Association of Anatomists.

[17]  L. Bonewald,et al.  Growth plate chondrocytes store latent transforming growth factor (TGF)‐β1 in their matrix through latent TGF‐β1 binding protein‐1 , 1998 .

[18]  Giuseppe M Peretti,et al.  Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair , 1998, Mechanisms of Development.

[19]  D. Davidson,et al.  Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud , 1998, Mechanisms of Development.

[20]  Mahlon D. Johnson,et al.  Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis , 1997, The Journal of cell biology.

[21]  C. Tabin,et al.  Molecular Models for Vertebrate Limb Development , 1997, Cell.

[22]  V. Lefebvre,et al.  Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis , 1997, Developmental dynamics : an official publication of the American Association of Anatomists.

[23]  Patrick P.L. Tam,et al.  SOX9 directly regulates the type-ll collagen gene , 1997, Nature Genetics.

[24]  P N Goodfellow,et al.  SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene , 1997, Molecular and cellular biology.

[25]  Clifford J. Tabin,et al.  Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein , 1996, Science.

[26]  B. Lanske,et al.  PTH/PTHrP Receptor in Early Development and Indian Hedgehog--Regulated Bone Growth , 1996, Science.

[27]  Y. Gañán,et al.  Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod. , 1996, Development.

[28]  M. Sporn,et al.  TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. , 1993, Developmental biology.

[29]  B. Thorp,et al.  Transforming growth factor-beta 1, -beta 2 and -beta 3 in cartilage and bone cells during endochondral ossification in the chick. , 1992, Development.

[30]  S. Bryant,et al.  Effects of localized application of transforming growth factor beta 1 on developing chick limbs. , 1991, Developmental biology.

[31]  J. Puzas,et al.  The production of transforming growth factor-beta by chick growth plate chondrocytes in short term monolayer culture. , 1990, Endocrinology.

[32]  R. Derynck,et al.  Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor. , 1986, Science.

[33]  L. Bonewald,et al.  Vitamin D3 metabolites regulate LTBP1 and latent TGF‐β1 expression and latent TGF‐β1 incorporation in the extracellular matrix of chondrocytes , 1999, Journal of cellular biochemistry.

[34]  D. Kingsley,et al.  The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. , 1994, Genes & development.