An Expert Opinion on Advanced Insulin Pump Use in Youth with Type 1 Diabetes.

Among children and adolescents with type 1 diabetes mellitus, the use of insulin pump therapy has increased since its introduction in the early 1980s. Optimal management of type 1 diabetes mellitus depends on sufficient understanding by patients, their families, and healthcare providers on how to use pump technology. The goal for the use of insulin pump therapy should be to advance proficiency over time from the basics taught at the initiation of pump therapy to utilizing advanced settings to obtain optimal glycemic control. However, this goal is often not met, and appropriate understanding of the full features of pump technology can be lacking. The objective of this review is to provide an expert perspective on the advanced features and use of insulin pump therapy, including practical guidelines for the successful use of insulin pump technology, and other considerations specific to patients and healthcare providers.

[1]  J. Edge,et al.  Can children with Type 1 diabetes and their caregivers estimate the carbohydrate content of meals and snacks? , 2009, Diabetic medicine : a journal of the British Diabetic Association.

[2]  K. Nørgaard,et al.  Effects of advanced carbohydrate counting in patients with Type 1 diabetes: a systematic review , 2014, Diabetic medicine : a journal of the British Diabetic Association.

[3]  Bruce W Bode,et al.  Diabetes management in the new millennium using insulin pump therapy , 2002, Diabetes/metabolism research and reviews.

[4]  Ewa Pańkowska,et al.  Application of novel dual wave meal bolus and its impact on glycated hemoglobin A1c level in children with type 1 diabetes , 2009, Pediatric diabetes.

[5]  Gian Vincenzo Zuccotti,et al.  Impact of new technologies on diabetes care. , 2015, World journal of diabetes.

[6]  D. B. Keenan,et al.  Accuracy of a New Real-Time Continuous Glucose Monitoring Algorithm , 2010, Journal of diabetes science and technology.

[7]  J. Shubrook,et al.  Insulin pumps: Beyond basal-bolus , 2015, Cleveland Clinic Journal of Medicine.

[8]  D. Golicki,et al.  The effect of using the insulin pump bolus calculator compared to standard insulin dosage calculations in patients with type 1 diabetes mellitus - systematic review. , 2013, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[9]  T. Jones,et al.  New Insights into Managing the Risk of Hypoglycaemia Associated with Intermittent High-Intensity Exercise in Individuals with Type 1 Diabetes Mellitus , 2007, Sports medicine.

[10]  J. Fairchild.  Changes in management and outcomes for children and adolescents with type 1 diabetes over the last 50 years , 2015, Journal of paediatrics and child health.

[11]  R. Porcher,et al.  Glucose response to intense aerobic exercise in type 1 diabetes: maintenance of near euglycemia despite a drastic decrease in insulin dose. , 2003, Diabetes care.

[12]  Eyal Dassau,et al.  Dynamic Insulin on Board: Incorporation of Circadian Insulin Sensitivity Variation , 2013, Journal of diabetes science and technology.

[13]  Claudio Cobelli,et al.  Diurnal Pattern of Insulin Action in Type 1 Diabetes , 2013, Diabetes.

[14]  M. Riddell,et al.  Preventing exercise-induced hypoglycemia in type 1 diabetes using real-time continuous glucose monitoring and a new carbohydrate intake algorithm: an observational field study. , 2011, Diabetes technology & therapeutics.

[15]  Francesca Annan,et al.  Exercise management in type 1 diabetes: a consensus statement. , 2017, The lancet. Diabetes & endocrinology.

[16]  M. Joubert,et al.  Personal continuous glucose monitoring (CGM) in diabetes management: review of the literature and implementation for practical use. , 2012, Diabetes research and clinical practice.

[17]  David Kerr,et al.  Insulin Pump Therapy With Automated Insulin Suspension in Response to Hypoglycemia , 2011, Diabetes Care.

[18]  S. Kwatra,et al.  The athlete with type I diabetes: managing insulin, diet and exercise. , 1996, American family physician.

[19]  N. Bratina,et al.  A New Horizon for Glucose Monitoring , 2015, Hormone Research in Paediatrics.

[20]  M. Colten,et al.  Effects of a Glucose Polymer Sports Drink on Blood Glucose, Insulin, and Performance in Subjects With Diabetes , 1996, The Diabetes educator.

[21]  Ambady Ramachandran,et al.  Hypoglycemia: The neglected complication , 2013, Indian journal of endocrinology and metabolism.

[22]  J. Pinsker,et al.  The role of continuous glucose monitoring in the care of children with type 1 diabetes , 2013, International Journal of Pediatric Endocrinology.

[23]  Stephen D Patek,et al.  Assessing sensor accuracy for non-adjunct use of continuous glucose monitoring. , 2015, Diabetes technology & therapeutics.

[24]  Bruce Buckingham,et al.  Continuous Glucose Monitoring: Current Use and Future Directions , 2013, Current Diabetes Reports.

[25]  David C Klonoff,et al.  Predictors of Hypoglycemia in the ASPIRE In-Home Study and Effects of Automatic Suspension of Insulin Delivery , 2015, Journal of diabetes science and technology.

[26]  S. Garg,et al.  Hypoglycemia Reduction and Changes in Hemoglobin A1c in the ASPIRE In-Home Study , 2015, Diabetes technology & therapeutics.

[27]  R. Beck,et al.  A contrast between children and adolescents with excellent and poor control: the T1D exchange clinic registry experience , 2014, Pediatric diabetes.

[28]  Masakazu Hirose,et al.  Quality of Life and Technology: Impact on Children and Families With Diabetes , 2012, Current Diabetes Reports.

[29]  C. Kenny.  When hypoglycemia is not obvious: diagnosing and treating under-recognized and undisclosed hypoglycemia. , 2014, Primary care diabetes.

[30]  D. Klonoff,et al.  Threshold-based insulin-pump interruption for reduction of hypoglycemia. , 2013, The New England journal of medicine.

[31]  Rajiv V Shah,et al.  Retrospective analysis of the real-world use of the threshold suspend feature of sensor-augmented insulin pumps. , 2015, Diabetes technology & therapeutics.

[32]  David M. Maahs,et al.  Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry , 2014, Diabetes Care.

[33]  K. Driscoll,et al.  Importance of Manually Entering Blood Glucose Readings When Wireless-Compatible Meters are Not Being Used with an Insulin Pump , 2013, Journal of diabetes science and technology.

[34]  Optimum bolus wizard settings in insulin pumps in children with Type 1 diabetes , 2016, Diabetic medicine : a journal of the British Diabetic Association.

[35]  Bruce W Bode,et al.  AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2016 OUTPATIENT GLUCOSE MONITORING CONSENSUS STATEMENT. , 2016, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[36]  Josep Vehí,et al.  Calculation of the Best Basal–Bolus Combination for Postprandial Glucose Control in Insulin Pump Therapy , 2011, IEEE Transactions on Biomedical Engineering.

[37]  T. Kawamura.  The importance of carbohydrate counting in the treatment of children with diabetes , 2007, Pediatric diabetes.

[38]  H. Chase,et al.  Preventing post-exercise nocturnal hypoglycemia in children with type 1 diabetes. , 2010, The Journal of pediatrics.

[39]  C. Sorli,et al.  Identifying and meeting the challenges of insulin therapy in type 2 diabetes , 2014, Journal of multidisciplinary healthcare.

[40]  Geoffrey McGarraugh.  Alarm Characterization for a Continuous Glucose Monitor That Replaces Traditional Blood Glucose Monitoring , 2010, Journal of diabetes science and technology.

[41]  Susana R. Patton,et al.  Continuous Glucose Monitoring Versus Self-monitoring of Blood Glucose in Children with Type 1 DiabetesThe Pros and Cons , 2012 .

[42]  S. Darcan,et al.  Effects of Carbohydrate Counting Method on Metabolic Control in Children with Type 1 Diabetes Mellitus , 2014, Journal of clinical research in pediatric endocrinology.

[43]  B. Bode.  Use of rapid-acting insulin analogues in the treatment of patients with type 1 and type 2 diabetes mellitus: insulin pump therapy versus multiple daily injections. , 2007, Clinical therapeutics.

[44]  M. Riddell,et al.  Clinical Management of the Physically Active Patient with Type 1 Diabetes , 2011, The Physician and sportsmedicine.