The neurite outgrowth inhibitor Nogo A is involved in autoimmune-mediated demyelination

[1]  S. Strittmatter,et al.  A new role for Nogo as a regulator of vascular remodeling , 2004, Nature Medicine.

[2]  R. Ransohoff,et al.  The Activation Status of Neuroantigen-specific T Cells in the Target Organ Determines the Clinical Outcome of Autoimmune Encephalomyelitis , 2004, The Journal of experimental medicine.

[3]  M. Schwab,et al.  Serum and cerebrospinal fluid antibodies to Nogo-A in patients with multiple sclerosis and acute neurological disorders , 2003, Journal of Neuroimmunology.

[4]  M. Schwab,et al.  Rapid induction of autoantibodies against Nogo‐A and MOG in the absence of an encephalitogenic T cell response: implication for immunotherapeutic approaches in neurological diseases , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[5]  P. Strata,et al.  Extrinsic regulation of injury/growth‐related gene expression in the inferior olive of the adult rat , 2003, The European journal of neuroscience.

[6]  Lawrence Steinman,et al.  Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis , 2003, Nature Biotechnology.

[7]  H. Ulmer,et al.  Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. , 2003, The New England journal of medicine.

[8]  Zhigang He,et al.  Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord , 2003, Molecular and Cellular Neuroscience.

[9]  O. Steward,et al.  Lack of Enhanced Spinal Regeneration in Nogo-Deficient Mice , 2003, Neuron.

[10]  R. Segal,et al.  p75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp , 2002, Nature.

[11]  Y. Okuda,et al.  The suppression of T cell apoptosis influences the severity of disease during the chronic phase but not the recovery from the acute phase of experimental autoimmune encephalomyelitis in mice , 2002, Journal of Neuroimmunology.

[12]  Moses Rodriguez,et al.  Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic‐progressive demyelinating disease , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[13]  Marco Domeniconi,et al.  Myelin-Associated Glycoprotein Interacts with the Nogo66 Receptor to Inhibit Neurite Outgrowth , 2002, Neuron.

[14]  Zhigang He,et al.  Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth , 2002, Nature.

[15]  S. Strittmatter,et al.  Nogo-66 receptor antagonist peptide promotes axonal regeneration , 2002, Nature.

[16]  M. Schwab,et al.  Patterns of Nogo mRNA and Protein Expression in the Developing and Adult Rat and After CNS Lesions , 2002, The Journal of Neuroscience.

[17]  E. Agranov,et al.  Vaccination with a Nogo-A-derived peptide after incomplete spinal-cord injury promotes recovery via a T-cell-mediated neuroprotective response: Comparison with other myelin antigens , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. McQualter,et al.  Granulocyte Macrophage Colony-Stimulating Factor A New Putative Therapeutic Target in Multiple Sclerosis , 2001 .

[19]  V. Dietz,et al.  Improving axonal growth and functional recovery after experimental spinal cord injury by neutralizing myelin associated inhibitors , 2001, Brain Research Reviews.

[20]  H. Weiner.  Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells. , 2001, Microbes and infection.

[21]  E. Agranov,et al.  Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease. , 2001, The Journal of clinical investigation.

[22]  J. Leonard,et al.  Myelin/axonal pathology in interleukin-12 induced serial relapses of experimental allergic encephalomyelitis in the Lewis rat. , 2001, The American journal of pathology.

[23]  B. Becher,et al.  The Clinical Course of Experimental Autoimmune Encephalomyelitis and Inflammation Is Controlled by the Expression of Cd40 within the Central Nervous System , 2001, The Journal of experimental medicine.

[24]  Manabu Onuki,et al.  Axonal degeneration is an early pathological feature in autoimmune‐mediated demyelination in mice , 2001, Microscopy research and technique.

[25]  A. Fournier,et al.  Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration , 2001, Nature.

[26]  M. Schwab,et al.  Regeneration of Lesioned Corticospinal Tract Fibers in the Adult Rat Induced by a Recombinant, Humanized IN-1 Antibody Fragment , 2000, The Journal of Neuroscience.

[27]  P. Strata,et al.  Application of Neutralizing Antibodies against NI-35/250 Myelin-Associated Neurite Growth Inhibitory Proteins to the Adult Rat Cerebellum Induces Sprouting of Uninjured Purkinje Cell Axons , 2000, The Journal of Neuroscience.

[28]  Fumio Nakamura,et al.  Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein , 2000, Nature.

[29]  L. Mckerracher,et al.  A Therapeutic Vaccine Approach to Stimulate Axon Regeneration in the Adult Mammalian Spinal Cord , 1999, Neuron.

[30]  S. Baranzini,et al.  B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. , 1999, Journal of immunology.

[31]  M. C. Acosta,et al.  Systemically administered interleukin-10 reduces tumor necrosis factor-alpha production and significantly improves functional recovery following traumatic spinal cord injury in rats. , 1999, Journal of neurotrauma.

[32]  J. Fawcett,et al.  The glial scar and central nervous system repair , 1999, Brain Research Bulletin.

[33]  B D Trapp,et al.  Axonal pathology in multiple sclerosis: relationship to neurologic disability. , 1999, Current opinion in neurology.

[34]  H. Weiner,et al.  IL-10 is critical in the regulation of automimmune encephalomyelitis as demonstrated by studies of IL-10 and IL-4 deficient and transgenic mice , 1998, Journal of Neuroimmunology.

[35]  S. Tonegawa,et al.  Tolerance Induction and Autoimmune Encephalomyelitis Amelioration After Administration of Myelin Basic Protein–derived Peptide , 1997, The Journal of experimental medicine.

[36]  Moses Rodriguez,et al.  Successful treatment of established relapsing experimental autoimmune encephalomyelitis in mice with a monoclonal natural autoantibody , 1997, Journal of Neuroimmunology.

[37]  T. Johns,et al.  Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis , 1997, Journal of Molecular Medicine.

[38]  L. Nicholson,et al.  Manipulation of the Th1/Th2 balance in autoimmune disease. , 1996, Current opinion in immunology.

[39]  J. Merrill,et al.  Cytokines in inflammatory brain lesions: helpful and harmful , 1996, Trends in Neurosciences.

[40]  A. Meyer-Franke,et al.  Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture , 1995, Neuron.

[41]  I. Cohen,et al.  Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor alpha secretion. , 1994, The Journal of clinical investigation.

[42]  B. Engelhardt,et al.  Induction of persistently demyelinated lesions in the rat following the repeated adoptive transfer of encephalitogenic T cells and demyelinating antibody , 1992, Journal of Neuroimmunology.

[43]  C. Bandtlow,et al.  Oligodendrocytes arrest neurite growth by contact inhibition , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[44]  David P. Corey,et al.  Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning , 1988, Neuron.

[45]  M. Schwab,et al.  Oligodendrocytes and CNS myelin are nonpermissive substrates for neurite growth and fibroblast spreading in vitro , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[46]  W. Norton,et al.  MYELINATION IN RAT BRAIN: METHOD OF MYELIN ISOLATION 1 , 1973, Journal of neurochemistry.

[47]  L. Steinman,et al.  Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy. , 2002, Annual review of neuroscience.

[48]  G. Wong,et al.  TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination , 1998, Nature Medicine.

[49]  C. Bernard,et al.  Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. , 1998, Autoimmunity.