The battle against perioperative glycaemic control: Hard to win?

© 2022 Indian Journal of Anaesthesia | Published by Wolters Kluwer Medknow In spite of so many advancements in the medical sciences, precise control of hyperglycaemia has always been a tough challenge for anaesthesiologists and intensivists. The battle to achieve euglycaemia in the intensive care unit (ICU) and operation theatres with newer oral and injectable drugs has witnessed varied results. Perioperative hyperglycaemia, especially a plasma glucose level above 180 mg/ dl, is an independent marker of poor clinical and surgical outcomes in both, the known diabetic and non-diabetic population.[1] The unwanted outcomes include delayed wound healing, an enhanced rate of wound infection, postoperative pulmonary complications, prolonged hospital stay and higher postoperative mortality. Hyperglycaemia (plasma glucose levels above 140 mg/dl) is common, with an occurrence of 20–40% in patients undergoing general surgery and the highest incidence of 80–90% in the cardiac surgical population.[2]

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