Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects
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S. Gogg | U. Smith | P. Jansson | A. Hammarstedt | V. Rotter Sopasakis | V. R. Sopasakis | Per-Anders Jansson | Ulf Smith
[1] S. Collins,et al. Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells. , 1997, Biochemical and biophysical research communications.
[2] Hui Chen,et al. Peroxisome Proliferator-activated Receptor-γ Represses GLUT4 Promoter Activity in Primary Adipocytes, and Rosiglitazone Alleviates This Effect* , 2003, Journal of Biological Chemistry.
[3] S. Gogg,et al. Thiazolidinediones (PPARγ agonists) but not PPAR α agonists increase IRS‐2 gene expression in 3T3‐L1 and human adipocytes 1 , 2001 .
[4] P. Puigserver,et al. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1 , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[5] V. Emilsson,et al. The effects of rexinoids and rosiglitazone on body weight and uncoupling protein isoform expression in the Zucker fa/fa rat. , 2000, Metabolism: clinical and experimental.
[6] P. Tontonoz,et al. Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target. , 2004, Journal of lipid research.
[7] R. Walczak,et al. Autoregulation of the Human Liver X Receptor α Promoter , 2001, Molecular and Cellular Biology.
[8] R. Saladin,et al. Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight. , 2000, Biochemical and biophysical research communications.
[9] Maia M. Jack,et al. Evidence of impaired adipogenesis in insulin resistance. , 2004, Biochemical and biophysical research communications.
[10] L. Sjöström,et al. Comparison of two methods for determining human adipose cell size. , 1972, Journal of lipid research.
[11] L. Groop,et al. Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[12] D. Loskutoff,et al. Monocyte chemoattractant protein 1 in obesity and insulin resistance , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[13] K. Umesono,et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. , 1998, The Journal of clinical investigation.
[14] B. Spiegelman,et al. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. , 2003, The Journal of clinical investigation.
[15] M. Ghazzi,et al. Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The Troglitazone Study Group. , 1997 .
[16] L. Sjöström,et al. Impact of obesity on metabolism in men and women. Importance of regional adipose tissue distribution. , 1983, The Journal of clinical investigation.
[17] J. Auwerx,et al. Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma. , 2004, Diabetes.
[18] U. Smith,et al. High local concentrations and effects on differentiation implicate interleukin-6 as a paracrine regulator. , 2004, Obesity research.
[19] M. Mozzoli,et al. Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes. , 2003, Metabolism: clinical and experimental.
[20] K. Wellen,et al. Obesity-induced inflammatory changes in adipose tissue. , 2003, The Journal of clinical investigation.
[21] T. Funahashi,et al. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). , 1996, Biochemical and biophysical research communications.
[22] Wei Chen,et al. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. , 2001, Diabetes.
[23] R. A. Norman,et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. , 2002, Diabetes.
[24] Weimin He,et al. Muscle-specific Pparg deletion causes insulin resistance , 2003, Nature Medicine.
[25] S. Gogg,et al. Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes. , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[26] L. Tartaglia,et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. , 2003, The Journal of clinical investigation.
[27] Philipp E. Scherer,et al. A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*) , 1995, The Journal of Biological Chemistry.
[28] J S Yudkin,et al. Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-�, in Vivo* , 2022 .
[29] B. Spiegelman,et al. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. , 1995, The Journal of clinical investigation.
[30] J. Auwerx,et al. Pioglitazone Induces In Vivo Adipocyte Differentiation in the Obese Zucker fa/fa Rat , 1997, Diabetes.
[31] A. Brookes,et al. Evidence for an important role of perilipin in the regulation of human adipocyte lipolysis , 2003, Diabetologia.
[32] M. Taskinen,et al. Postprandial Hypertriglyceridemia and Insulin Resistance in Normoglycemic First-Degree Relatives of Patients with Type 2 Diabetes , 1999, Annals of Internal Medicine.
[33] P. Pekala,et al. Regulation of GLUT4 Gene Expression by Arachidonic Acid , 1996, The Journal of Biological Chemistry.
[34] G. Shulman,et al. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver , 2001, Nature.
[35] U. Smith,et al. Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance. , 2003, Biochemical and biophysical research communications.
[36] U. Smith,et al. Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects* , 2003, Journal of Biological Chemistry.
[37] R. DeFronzo,et al. Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.
[38] T. Funahashi,et al. A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[39] J. Gustafsson,et al. Expression of the Insulin-responsive Glucose Transporter GLUT4 in Adipocytes Is Dependent on Liver X Receptor α* , 2003, Journal of Biological Chemistry.
[40] H. von Schenck,et al. Early posthypoglycemic insulin resistance in man is mainly an effect of beta-adrenergic stimulation. , 1987, The Journal of clinical investigation.
[41] M. Desai,et al. Obesity is associated with macrophage accumulation in adipose tissue. , 2003, The Journal of clinical investigation.
[42] T. Fujiwara,et al. Characterization of New Oral Antidiabetic Agent CS-045: Studies in KK and ob/ob Mice and Zucker Fatty Rats , 1988, Diabetes.
[43] H C Lukaski,et al. Validation of tetrapolar bioelectrical impedance method to assess human body composition. , 1986, Journal of applied physiology.
[44] U. Smith,et al. Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[45] J. Capeau,et al. Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone. , 2003, Biochemical and biophysical research communications.
[46] B. Spiegelman,et al. AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity (*) , 1996, The Journal of Biological Chemistry.
[47] P. Jansson,et al. insulin resistance with low cellular IRS‐1 expression is also associated with low GLUT4 expression and impaired insulin‐stimulated glucose transport 1 , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[48] R. Plodkowski,et al. Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. , 2002, Diabetes.
[49] 古田 雅彦. Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus , 2002 .
[50] John A Wagner,et al. Complex Distribution, Not Absolute Amount of Adiponectin, Correlates with Thiazolidinedione-mediated Improvement in Insulin Sensitivity* , 2004, Journal of Biological Chemistry.