EVOKED POTENTIALS IN INFANT BRAINSTEM SYNDROME ASSOCIATED WITH ARNOLD‐CHIARI MALFORMATION

This study evaluated the contribution of brainstem auditory evoked potentials (BAEPs) and median nerve somatosensory evoked potentials (SEPs) to the assessment of brainstem dysfunction in infants with myelomeningocele and Arnold‐Chiari malformation. 16 infants under one year of age were studied. Six had infant brainstem syndrome (IBS). 11 had abnormally prolonged I‐V interwave latency (brainstem transmission time, BSTT); BSTT did not differentiate those patients with and without IBS. The cortical ‘N20′ component of the median‐nerve SEPs was absent or had low amplitude and prolonged latency in all six patients with clinical signs of brainstem dysfunction and in four without. Median‐nerve SEPs were normal in the patients without IBS. There was a significant difference between patients with and without IBS. Median‐nerve SEPs may be a helpful measure of brainstem function in infants with Arnold‐Chiari malformation.

[1]  R. Gilmore.  Review Article: The Use of Somatosensory Evoked Potentials in Infants and Children , 1989 .

[2]  R. Gilmore.  Use of somatosensory evoked potentials in infants and children. , 1988, Neurologic clinics.

[3]  M. Taylor,et al.  SEPs to median nerve stimulation: normative data for paediatrics. , 1988, Electroencephalography and clinical neurophysiology.

[4]  J. Hecht,et al.  Neurological basis of respiratory complications in achondroplasia , 1988, Annals of neurology.

[5]  B. Rosenblatt,et al.  A longitudinal study of short latency somatosensory evoked responses in healthy newborns and infants. , 1988, Electroencephalography and clinical neurophysiology.

[6]  E. Sedgwick,et al.  Brainstem auditory evoked potential abnormalities in myelomeningocoele in the older child. , 1987, Journal of neurology, neurosurgery, and psychiatry.

[7]  R. Pyeritz,et al.  Cervicomedullary compression in young patients with achondroplasia: value of comprehensive neurologic and respiratory evaluation. , 1987, The Journal of pediatrics.

[8]  J. Lütschg,et al.  Brainstem auditory evoked potentials in meningomyelocele. , 1985, Neuropediatrics.

[9]  D. Pillsbury,et al.  Brain stem auditory evoked potentials in Arnold-Chiari malformation: possible prognostic value and changes with surgical decompression. , 1985, Neurosurgery.

[10]  H. Rekate,et al.  Relationship of CSF shunting and IQ in children with myelomeningocele: a retrospective analysis. , 1984, Child's brain.

[11]  J. Stone,et al.  Clinical and electrophysiologic recovery in Arnold-Chiari malformation. , 1983, Surgical neurology.

[12]  J. Stockard,et al.  Prognostic value of brainstem auditory evoked potentials in neonates. , 1983, Archives of neurology.

[13]  A. Barnet,et al.  Auditory, Visual, and Somatosensory Evoked Potentials in Pediatric Diagnosis , 1979 .

[14]  D. Bruce,et al.  The Arnold-Chiari malformation. , 1978, The Orthopedic clinics of North America.

[15]  D. Reigel,et al.  Intra‐operative Evoked Potential Studies of Newborn Infants with Myelomeningocele , 1976, Developmental medicine and child neurology. Supplement.