Motor aspects of speech imparment in parkinson ‘ s disease and their assessment

patients with parkinson’s disease (pd) often suffer from hypokinetic dysarthria (hd) involving impairment of phonation, articulation, prosody and speech fluency. our paper focuses on parameters used to evaluate motor aspects of speech and on methods of relevant data collection and analysis. an overview of specific parameters of hd and methods used for its evaluation may facilitate development of a diagnostic system for hd and of suitable measures for the assessment of its progression. J. Mekyska1, Z. Smékal1, M. Košťálová3,4, M. Mračková2,3, S. Skutilová4, I. Rektorová2,3 1 splab, Ústav telekomunikací, fekt vut v Brně 2 i. neurologická klinika lf Mu a fn u sv. anny v Brně 3 ceitec Mu, Brno 4 neurologická klinika

[1]  A. Stracciari,et al.  Development of palilalia after stereotaxic thalamotomy in Parkinson's disease. , 1993, European neurology.

[2]  A. Goberman,et al.  Acoustic analysis of clear versus conversational speech in individuals with Parkinson disease. , 2005, Journal of communication disorders.

[3]  J. Hillenbrand,et al.  Acoustic characteristics of American English vowels. , 1994, The Journal of the Acoustical Society of America.

[4]  S. Skodda,et al.  Progression of dysprosody in Parkinson's disease over time—A longitudinal study , 2009, Movement disorders : official journal of the Movement Disorder Society.

[5]  Raymond D. Kent,et al.  Parametric quantitative acoustic analysis of conversation produced by speakers with dysarthria and healthy speakers. , 2006, Journal of speech, language, and hearing research : JSLHR.

[6]  Hermann Ackermann,et al.  Gender-Specific Vocal Dysfunctions in Parkinson's Disease: Electroglottographic and Acoustic Analyses , 1995, The Annals of otology, rhinology, and laryngology.

[7]  N. Solomon,et al.  Speech breathing in Parkinson's disease. , 1993, Journal of speech and hearing research.

[8]  P. Boon,et al.  The effect of levodopa on respiration and word intelligibility in people with advanced Parkinson's disease , 2007, Clinical Neurology and Neurosurgery.

[9]  J. Jankovic,et al.  Functional decline in Parkinson disease. , 2001, Archives of neurology.

[10]  A. Goberman,et al.  Voice onset time in Parkinson disease. , 2010, Journal of communication disorders.

[11]  A. Goberman,et al.  Fundamental frequency change during offset and onset of voicing in individuals with Parkinson disease. , 2008, Journal of voice : official journal of the Voice Foundation.

[12]  G. Weismer,et al.  Kinematic, acoustic, and perceptual analyses of connected speech produced by parkinsonian and normal geriatric adults. , 1989, The Journal of the Acoustical Society of America.

[13]  P. Kuhl,et al.  The effect of reduced vowel working space on speech intelligibility in Mandarin-speaking young adults with cerebral palsy. , 2005, The Journal of the Acoustical Society of America.

[14]  J. Peragut,et al.  Effects of Pharmacological versus Electrophysiological Treatments on Parkinsonian Dysprosody , 2002 .

[15]  A. Lang,et al.  Parkinson's disease. First of two parts. , 1998, The New England journal of medicine.

[16]  M. Hoehn,et al.  Parkinsonism , 1967, Neurology.

[17]  C. Coelho,et al.  Phonatory characteristics of parkinsonian speech before and after morning medication: the ON and OFF states. , 2002, Journal of communication disorders.

[18]  H. Teager Some observations on oral air flow during phonation , 1980 .

[19]  L. Lisker,et al.  A Cross-Language Study of Voicing in Initial Stops: Acoustical Measurements , 1964 .

[20]  E. Metter,et al.  Clinical and acoustical variability in hypokinetic dysarthria. , 1986, Journal of communication disorders.

[21]  C. Coelho,et al.  Acoustic analysis of parkinsonian speech I: speech characteristics and L-Dopa therapy. , 2002, NeuroRehabilitation.

[22]  K. Spencer,et al.  Speech motor programming in hypokinetic and ataxic dysarthria , 2005, Brain and Language.

[23]  P. Snyder,et al.  Variability in fundamental frequency during speech in prodromal and incipient Parkinson's disease: A longitudinal case study , 2004, Brain and Cognition.

[24]  K. Yorkston,et al.  Speech and pause characteristics following speech rate reduction in hypokinetic dysarthria. , 1996, Journal of communication disorders.

[25]  L. Hartelius,et al.  Speech and swallowing symptoms associated with Parkinson's disease and multiple sclerosis: a survey. , 1994, Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics.

[26]  J. Logemann,et al.  Frequency and cooccurrence of vocal tract dysfunctions in the speech of a large sample of Parkinson patients. , 1978, The Journal of speech and hearing disorders.

[27]  Sandra E. Black,et al.  Acoustic analysis in the differentiation of Parkinson's disease and major depression , 1992, Journal of psycholinguistic research.

[28]  R Iansek,et al.  Regulation of parkinsonian speech volume: the effect of interlocuter distance , 1999, Journal of neurology, neurosurgery, and psychiatry.

[29]  J. Ryalls,et al.  A Comparison of the Prosodic Characteristics of the Speech of People with Parkinson’s Disease and Friedreich’s Ataxia with Neurologically Normal Speakers , 1998, Folia Phoniatrica et Logopaedica.

[30]  Michael P. Robb,et al.  Prosodic characteristics of Parkinsonian speech: the effect of levodopa-based medication , 2005 .

[31]  Raymond D. Kent,et al.  Toward an acoustic typology of motor speech disorders , 2003, Clinical linguistics & phonetics.

[32]  G. Canter SPEECH CHARACTERISTICS OF PATIENTS WITH PARKINSON'S DISEASE. 3. ARTICULATION, DIADOCHOKINESIS, AND OVER-ALL SPEECH ADEQUACY. , 1965, The Journal of speech and hearing disorders.

[33]  Christy L. Ludlow,et al.  Speech timing in Parkinson's and Huntington's disease , 1987, Brain and Language.

[34]  K. Tjaden,et al.  Characteristics of Diadochokinesis in Multiple Sclerosis and Parkinson’s Disease , 2003, Folia Phoniatrica et Logopaedica.

[35]  A. Goberman,et al.  Correlation between acoustic speech characteristics and non-speech motor performance in Parkinson Disease. , 2005, Medical science monitor : international medical journal of experimental and clinical research.

[36]  Howard Poizner,et al.  Articulatory Consequences of Parkinson's Disease: Perspectives from Two Modalities , 1999, Brain and Cognition.

[37]  G. Canter SPEECH CHARACTERISTICS OF PATIENTS WITH PARKINSON'S DISEASE: I. INTENSITY, PITCH, AND DURATION. , 1963, The Journal of speech and hearing disorders.

[38]  Raymond D. Kent,et al.  The dysarthrias: Speech-voice profiles, related dysfunctions, and neuropathology , 1998 .

[39]  H. Hirose,et al.  Pathophysiology of motor speech disorders (dysarthria). , 1986, Folia phoniatrica.

[40]  O. Hornykiewicz Biochemical aspects of Parkinson's disease , 1998, Neurology.

[41]  A. Hughes,et al.  Voice characteristics in the progression of Parkinson's disease. , 2000, International journal of language & communication disorders.

[42]  L. Capus,et al.  ‘Speech Initiation Hesitation’ following Subthalamic Nucleus Stimulation in a Patient with Parkinson’s Disease , 2003, European Neurology.

[43]  Hermann Ackermann,et al.  The Temporal Control of Repetitive Articulatory Movements in Parkinson's Disease , 1997, Brain and Language.

[44]  M. Van der Linden,et al.  The interpretation of dysprosody in patients with Parkinson's disease. , 1991, Journal of neurology, neurosurgery, and psychiatry.

[45]  S. Skodda,et al.  Short- and long-term dopaminergic effects on dysarthria in early Parkinson’s disease , 2010, Journal of Neural Transmission.

[46]  Karl Herholz,et al.  Nonlinear progression of Parkinson disease as determined by serial positron emission tomographic imaging of striatal fluorodopa F 18 activity. , 2005, Archives of neurology.

[47]  Jack J. Jiang,et al.  Acoustic analysis of the tremulous voice: assessing the utility of the correlation dimension and perturbation parameters. , 2010, Journal of communication disorders.

[48]  Kate Bunton,et al.  Segmental Level Analysis of Laryngeal Function in Persons with Motor Speech Disorders , 2002, Folia Phoniatrica et Logopaedica.

[49]  Q. Summerfield Articulatory rate and perceptual constancy in phonetic perception. , 1981, Journal of experimental psychology. Human perception and performance.

[50]  R Iansek,et al.  Motor instability in parkinsonian speech intensity. , 2001, Neuropsychiatry, neuropsychology, and behavioral neurology.

[51]  T. Paus,et al.  Functional abnormalities in the primary orofacial sensorimotor cortex during speech in Parkinson's disease , 2007, Movement disorders : official journal of the Movement Disorder Society.

[52]  P. Zwirner,et al.  Vocal tract steadiness: a measure of phonatory and upper airway motor control during phonation in dysarthria. , 1992, Journal of speech and hearing research.

[53]  Raymond D. Kent,et al.  Laryngeal dysfunction in neurological disease : amyotrophic lateral sclerosis, parkinson disease, and stroke , 1994 .

[54]  M. Gentil,et al.  The Effect of Levodopa on Vocal Function in Parkinson's Disease , 2001, Clinical neuropharmacology.

[55]  A. Reeves,et al.  Speaking Rate and Segments: A Look at the Relation between Speech Production and Speech Perception for the Voicing Contrast , 1986 .

[56]  J. Logemann,et al.  Vocal Tract Control in Parkinson's Disease , 1981 .

[57]  S G Fletcher,et al.  Time-by-count measurement of diadochokinetic syllable rate. , 1972, Journal of speech and hearing research.

[58]  E. Růžička,et al.  Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson's disease. , 2011, The Journal of the Acoustical Society of America.

[59]  R. Iansek,et al.  Speech volume regulation in Parkinson’s disease: effects of implicit cues and explicit instructions , 1999, Neuropsychologia.