The integrated processes of hard tissue regeneration with special emphasis on fracture healing.

[1]  J. Wozney,et al.  Maxillary alveolar cleft repair in dogs using recombinant human bone morphogenetic protein-2 and a polymer carrier. , 1996, Plastic and reconstructive surgery.

[2]  J. Wozney,et al.  Poly(α-hydroxy acid) carrier for delivering recombinant human bone morphogenetic protein-2 for bone regeneration , 1996 .

[3]  J. Hollinger,et al.  A Bone Regeneration Study: Transforming Growth Factor‐β1 and Its Delivery , 1996 .

[4]  M. Bostrom,et al.  Osseous regeneration in preclinical models using bioabsorbable delivery technology for recombinant human bone morphogenetic protein 2 (rhBMP-2) , 1995 .

[5]  T A Einhorn,et al.  The expression of cytokine activity by fracture callus , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[6]  T A Einhorn,et al.  Enhancement of fracture-healing. , 1995, The Journal of bone and joint surgery. American volume.

[7]  A. Weiland,et al.  Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[8]  S D Cook,et al.  Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. , 1995, The Journal of bone and joint surgery. American volume.

[9]  D. Carey,et al.  Expression of bone morphogenetic protein‐6 messenger RNA in bovine growth plate chondrocytes of different size , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  W. Border,et al.  Transforming Growth Factor β in Tissue Fibrosis , 1994 .

[11]  D. Davy,et al.  The effect of osteogenin (a bone morphogenetic protein) on the formation of bone in orthotopic segmental defects in rats. , 1994, The Journal of bone and joint surgery. American volume.

[12]  J. Hollinger,et al.  Osseous regeneration in the rat calvarium using novel delivery systems for recombinant human bone morphogenetic protein-2 (rhBMP-2). , 1994, Journal of biomedical materials research.

[13]  J. Hollinger,et al.  Recombinant human bone morphogenetic protein-2 is superior to demineralized bone matrix in repairing craniotomy defects in rats. , 1994, Journal of biomedical materials research.

[14]  A. Reddi Bone and cartilage differentiation. , 1994, Current opinion in genetics & development.

[15]  S. Cook,et al.  The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects. , 1994, The Journal of bone and joint surgery. American volume.

[16]  H. Steenfos,et al.  Growth factors and wound healing. , 1994, Scandinavian journal of plastic and reconstructive surgery and hand surgery.

[17]  K. Takaoka,et al.  Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing , 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  R. O’Keefe,et al.  Effects of transforming growth factor‐β1 and fibroblast growth factor on DNA synthesis in growth plate chondrocytes are enhanced by insulin‐like growth factor‐I , 1994 .

[19]  R. Miller,et al.  Basic fibroblast growth factor binds to heparan sulfate in the extracellular matrix of rat growth plate chondrocytes. , 1994, Archives of biochemistry and biophysics.

[20]  R. Allman,et al.  A phase II study to evaluate recombinant platelet-derived growth factor-BB in the treatment of stage 3 and 4 pressure ulcers. , 1994, Archives of surgery.

[21]  A. Reddi,et al.  Platelet-derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects. , 1993, The Journal of clinical investigation.

[22]  Robinson Cj Growth factors: therapeutic advances in wound healing. , 1993, Annals of medicine.

[23]  D B Kimmel,et al.  A paradigm for skeletal strength homeostasis , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[24]  W. T. Bourque,et al.  Expression of four growth factors during fracture repair. , 1993, The International journal of developmental biology.

[25]  Subburaman Mohan,et al.  Growth factors to stimulate bone formation , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[26]  G. Mundy Cytokines and growth factors in the regulation of bone remodeling , 1993, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  G. Pierce,et al.  Role of platelet‐derived growth factor in osteoblast function and bone synthesis , 1993, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[28]  E. Wang,et al.  Healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein. , 1993, Clinical orthopaedics and related research.

[29]  J. Hollinger Factors for osseous repair and delivery: Part II. , 1993, The Journal of craniofacial surgery.

[30]  E. Vuorio,et al.  Gene expression during bone repair. , 1993, Clinical orthopaedics and related research.

[31]  T. Tanaka,et al.  Morphological study of recombinant human transforming growth factor beta 1-induced intramembranous ossification in neonatal rat parietal bone. , 1993, Bone.

[32]  T. Einhorn,et al.  i) The biochemistry of fracture healing , 1992 .

[33]  M. Klagsbrun,et al.  Interaction of basic fibroblast growth factor with bovine growth plate chondrocytes , 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[34]  Mark E. Bolander,et al.  Regulation of Fracture Repair by Growth Factors , 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[35]  G F Pierce,et al.  Platelet-derived growth factor (BB homodimer), transforming growth factor-beta 1, and basic fibroblast growth factor in dermal wound healing. Neovessel and matrix formation and cessation of repair. , 1992, The American journal of pathology.

[36]  J. Wozney,et al.  The bone morphogenetic protein family and osteogenesis , 1992, Molecular reproduction and development.

[37]  I. Otterness,et al.  Transition from interleukin 1 beta (IL-1 beta) to IL-1 alpha production during maturation of inflammatory macrophages in vivo , 1992, The Journal of experimental medicine.

[38]  V. Rosen,et al.  The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. , 1992, The Journal of bone and joint surgery. American volume.

[39]  E. Canalis,et al.  Isoform-specific regulation of platelet-derived growth factor activity and binding in osteoblast-enriched cultures from fetal rat bone. , 1992, The Journal of clinical investigation.

[40]  D. Lorich,et al.  The pericyte as a possible osteoblast progenitor cell. , 1992, Clinical orthopaedics and related research.

[41]  A. Rogers European Community: Tobacco advertising ban delayed , 1992, The Lancet.

[42]  L. Phillips,et al.  Platelet-derived growth factor BB for the treatment of chronic pressure ulcers , 1992, The Lancet.

[43]  E. Amento,et al.  Rapid publication TGF‐β1 induces bone closure of skull defects , 1991 .

[44]  E. Wang,et al.  Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. , 1991, Archives of otolaryngology--head & neck surgery.

[45]  E. Canalis,et al.  Transforming growth factor-beta and remodeling of bone. , 1991, The Journal of bone and joint surgery. American volume.

[46]  A. Ammann,et al.  In vivo induction of bone by recombinant human transforming growth factor β1 , 1991 .

[47]  M S Reddy,et al.  The effects of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. , 1991, Journal of periodontology.

[48]  S. Vukicevic,et al.  Transforming growth factor beta type 1 binds to collagen IV of basement membrane matrix: implications for development. , 1991, Developmental biology.

[49]  Thomas A. Mustoe, MD, FACS,et al.  Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model. , 1991, The Journal of clinical investigation.

[50]  O. Wahlström,et al.  Effect of platelet derived growth factor on heterotopic bone formation in rats. , 1991, Acta orthopaedica Scandinavica.

[51]  M. Sporn,et al.  TGF-beta: problems and prospects. , 1990, Cell regulation.

[52]  S. Goldring,et al.  Skeletal tissue response to cytokines. , 1990, Clinical orthopaedics and related research.

[53]  J. Mulliken,et al.  The healing of bone and cartilage. , 1990, Clinics in plastic surgery.

[54]  G. Pierce Macrophages: important physiologic and pathologic sources of polypeptide growth factors. , 1990, American journal of respiratory cell and molecular biology.

[55]  V. Rosen,et al.  Growth factors influencing bone development , 1990, Journal of Cell Science.

[56]  H. Antoniades,et al.  A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. , 1989, Journal of clinical periodontology.

[57]  M. Noda,et al.  In vivo stimulation of bone formation by transforming growth factor-beta. , 1989, Endocrinology.

[58]  D. Connolly,et al.  Enhancement of angiogenesis by bFGF in mandibular bone graft healing in the rabbit. , 1988, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[59]  K. Takaoka,et al.  Prognostic significance of bone morphogenetic activity in osteosarcoma tissue , 1988, Cancer.

[60]  J O Hollinger,et al.  The critical size defect as an experimental model for craniomandibulofacial nonunions. , 1986, Clinical orthopaedics and related research.

[61]  K. Takaoka,et al.  Clinical significance of bone morphogenetic activity in osteosarcoma. A study of 20 cases , 1985, Cancer.

[62]  B. Mckibbin,et al.  The biology of fracture healing in long bones. , 1978, The Journal of bone and joint surgery. British volume.

[63]  J. Trueta,et al.  The role of the vessels in osteogenesis , 1963 .

[64]  J. Buckwalter,et al.  Bone biology. I: Structure, blood supply, cells, matrix, and mineralization. , 1996, Instructional course lectures.

[65]  M J Glimcher,et al.  Bone biology. II: Formation, form, modeling, remodeling, and regulation of cell function. , 1996, Instructional course lectures.

[66]  K. Leong,et al.  Poly(α-hydroxy acids). Carriers for bone morphogenetic proteins , 1996 .

[67]  D. Kingsley,et al.  The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. , 1994, Genes & development.

[68]  M. S. Sørensen Temporal bone dynamics, the hard way. Formation, growth, modeling, repair and quantum type bone remodeling in the otic capsule. , 1994, Acta oto-laryngologica. Supplementum.

[69]  Gary E. Friedlaender,et al.  Bone formation and repair , 1994 .

[70]  A. Huvos,et al.  Expression of bone morphogenetic proteins in human osteosarcoma. Immunohistochemical detection with monoclonal antibody , 1994, Cancer.

[71]  L. Mosekilde,et al.  The effects of growth hormone on fracture healing in rats: a histological description. , 1993, Bone.

[72]  J. Massagué,et al.  The transforming growth factor-beta family. , 1990, Annual review of cell biology.

[73]  M. Bolander,et al.  Transforming growth factor-beta in the regulation of fracture repair. , 1990, The Orthopedic clinics of North America.

[74]  L. Bonewald,et al.  Role of transforming growth factor-beta in bone remodeling. , 1990, Clinical orthopaedics and related research.

[75]  E. Vuorio,et al.  In situ localization of collagen production by chondrocytes and osteoblasts in fracture callus. , 1989, The Journal of bone and joint surgery. American volume.

[76]  B. Spiessl,et al.  New Concepts in Maxillofacial Bone Surgery , 1976, Springer Berlin Heidelberg.