Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells
暂无分享,去创建一个
B. Katzenellenbogen | L. Walker | Shabana I. Khan | I. Khan | W. Helferich | B. Avula | A. Dasmahapatra | Pranapda Aumsuwan
[1] Y. Ho,et al. Antroquinonol D, isolated from Antrodia camphorata, with DNA demethylation and anticancer potential. , 2014, Journal of agricultural and food chemistry.
[2] Qi Xie,et al. Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells , 2014, Genes, chromosomes & cancer.
[3] K. Ayyanathan. Potential Utility of Natural Products as Regulators of Breast Cancer-Associated Aromatase Promoters , 2014 .
[4] Z. Ali,et al. Characterization of Steroidal Saponins from Dioscorea villosa and D. cayenensis Using Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry , 2014, Planta Medica.
[5] P. Smolewski,et al. Clofarabine, a novel adenosine analogue, reactivates DNA methylation-silenced tumour suppressor genes and inhibits cell growth in breast cancer cells. , 2014, European journal of pharmacology.
[6] M. van den Berg,et al. Phytoestrogens in menopausal supplements induce ER-dependent cell proliferation and overcome breast cancer treatment in an in vitro breast cancer model. , 2013, Toxicology and applied pharmacology.
[7] M. Kettler,et al. Male breast disease: pictorial review with radiologic-pathologic correlation. , 2013, Radiographics : a review publication of the Radiological Society of North America, Inc.
[8] Fan Shen,et al. Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry. , 2013, Clinical chemistry.
[9] Z. Ali,et al. Cholestane steroid glycosides from the rhizomes of Dioscorea villosa (wild yam). , 2013, Carbohydrate research.
[10] Z. Ling,et al. Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation , 2013, Oncogene.
[11] Z. Werb,et al. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression , 2013, Nature Cell Biology.
[12] Y. Tamaki,et al. Clinicopathological analysis of GATA3-positive breast cancers with special reference to response to neoadjuvant chemotherapy. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[13] V. Stearns,et al. Epigenetics as a Therapeutic Target in Breast Cancer , 2012, Journal of Mammary Gland Biology and Neoplasia.
[14] H. Aburatani,et al. Loss of 5‐hydroxymethylcytosine is accompanied with malignant cellular transformation , 2012, Cancer science.
[15] L. Walker,et al. Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome. , 2012, Chemical research in toxicology.
[16] M. Balasubramanian,et al. Diosgenin, a steroidal saponin, exhibits anticancer activity by attenuating lipid peroxidation via enhancing antioxidant defense system during NMU-induced breast carcinoma. , 2012, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
[17] Peng Huang,et al. Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence. , 2011, Cancer research.
[18] Chuan He,et al. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine , 2011, Science.
[19] Yang Wang,et al. Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA , 2011, Science.
[20] Georgia Sotiropoulou,et al. DNA methylation of tumor suppressor and metastasis suppressor genes in circulating tumor cells. , 2011, Clinical chemistry.
[21] C. Iacobuzio-Donahue,et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers , 2011, Oncotarget.
[22] P. Neven,et al. BREAST CANCER PREVENTION: LIFESTYLE CHANGES AND CHEMOPREVENTION , 2011, Acta clinica Belgica.
[23] L. Walker,et al. Potential utility of natural products as regulators of breast cancer-associated aromatase promoters , 2011, Reproductive biology and endocrinology : RB&E.
[24] Krishna R. Kalari,et al. Integrated Analysis of Gene Expression, CpG Island Methylation, and Gene Copy Number in Breast Cancer Cells by Deep Sequencing , 2011, PloS one.
[25] J. Medina-Franco,et al. Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach , 2010, Molecular Diversity.
[26] Steve Horvath,et al. Higher levels of GATA3 predict better survival in women with breast cancer. , 2010, Human pathology.
[27] Z. Ali,et al. Teratogenic effects of blue cohosh (Caulophyllum thalictroides) in Japanese medaka (Oryzias latipes) are probably mediated through GATA2/EDN1 signaling pathway. , 2010, Chemical research in toxicology.
[28] L. Kastl,et al. Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells. , 2010, International journal of oncology.
[29] Stefano Amatori,et al. DNA demethylating antineoplastic strategies: a comparative point of view. , 2010, Genes & cancer.
[30] K. Bystricky,et al. The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer , 2010, Journal of Mammary Gland Biology and Neoplasia.
[31] M. Esteller,et al. Breast Cancer Epigenetics: From DNA Methylation to microRNAs , 2010, Journal of Mammary Gland Biology and Neoplasia.
[32] D. Bell. Our changing view of the genomic landscape of cancer , 2009, The Journal of pathology.
[33] Peter A. Jones,et al. Epigenetics in cancer. , 2010, Carcinogenesis.
[34] W. Grizzle,et al. Biomarkers and the genetics of early neoplastic lesions. , 2010, Cancer biomarkers : section A of Disease markers.
[35] J. Keen,et al. The RNA-binding protein HuR regulates GATA3 mRNA stability in human breast cancer cell lines , 2010, Breast Cancer Research and Treatment.
[36] Michele D. Sobolewski,et al. Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells , 2010, Breast Cancer Research and Treatment.
[37] R. Weigel,et al. GATA-3 as a marker of hormone response in breast cancer. , 2009, The Journal of surgical research.
[38] Manfred Schmitt,et al. DNA methylation as a biomarker in breast cancer. , 2009, Future oncology.
[39] W. Holzgreve,et al. Methylation profiles of 22 candidate genes in breast cancer using high-throughput MALDI-TOF mass array , 2009, Oncogene.
[40] David R. Liu,et al. Conversion of 5-Methylcytosine to 5- Hydroxymethylcytosine in Mammalian DNA by the MLL Partner TET1 , 2009 .
[41] N. Heintz,et al. The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain , 2009, Science.
[42] D. Newman,et al. Nature: a vital source of leads for anticancer drug development , 2009, Phytochemistry Reviews.
[43] W. Ahn,et al. Estrogen activities and the cellular effects of natural progesterone from wild yam extract in mcf-7 human breast cancer cells. , 2009, The American journal of Chinese medicine.
[44] T. Molinski,et al. Drug development from marine natural products , 2009, Nature Reviews Drug Discovery.
[45] I. Khan,et al. Disruption of circulation by ethanol promotes fetal alcohol spectrum disorder (FASD) in medaka (Oryzias latipes) embryogenesis. , 2008, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
[46] Susan J. Clark,et al. Breast cancer epigenetics: normal human mammary epithelial cells as a model system , 2008, Journal of Molecular Medicine.
[47] A. Ganesan. The impact of natural products upon modern drug discovery. , 2008, Current opinion in chemical biology.
[48] David J Newman,et al. Natural products as leads to potential drugs: an old process or the new hope for drug discovery? , 2008, Journal of medicinal chemistry.
[49] M. Esteller. Epigenetics in cancer. , 2008, The New England journal of medicine.
[50] M. Butler. Natural products to drugs: natural product-derived compounds in clinical trials. , 2005, Natural product reports.
[51] J. Keen,et al. Trichostatin A and 5 Aza-2′ deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR , 2008, Breast Cancer Research and Treatment.
[52] Jen-kun Lin,et al. Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2‐overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation , 2007, FEBS letters.
[53] R. Kiyama,et al. Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root. , 2007, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[54] W. Kitching,et al. Complete 1H and 13C assignments of the four major saponins from Dioscorea villosa (wild yam) , 2007, Magnetic resonance in chemistry : MRC.
[55] Kornelia Polyak,et al. Breast cancer: origins and evolution. , 2007, The Journal of clinical investigation.
[56] Akihiko Koga,et al. Targeted reduction of the DNA methylation level with 5-azacytidine promotes excision of the medaka fish Tol2 transposable element. , 2006, Genetical research.
[57] D. Carroll. Nonhormonal therapies for hot flashes in menopause. , 2006, American family physician.
[58] M. Lacaille‐Dubois,et al. Steroidal saponins and flavan-3-ol glycosides from Dioscorea villosa , 2006 .
[59] J. Peedicayil. Epigenetic therapy--a new development in pharmacology. , 2006, The Indian journal of medical research.
[60] B. Zhu,et al. Mechanisms for the Inhibition of DNA Methyltransferases by Tea Catechins and Bioflavonoids , 2005, Molecular Pharmacology.
[61] Dioscorea Villosa. Final report of the amended safety assessment of Dioscorea Villosa (Wild Yam) root extract. , 2004, International journal of toxicology.
[62] Ni Ai,et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. , 2003, Cancer research.
[63] D. Tripathy,et al. Traditional Chinese medicine in the treatment of breast cancer. , 2002, Seminars in oncology.
[64] Martin Widschwendter,et al. DNA methylation and breast carcinogenesis , 2002, Oncogene.
[65] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[66] M. Esteller. Epigenetic lesions causing genetic lesions in human cancer: promoter hypermethylation of DNA repair genes. , 2000, European journal of cancer.
[67] T. Bestor,et al. The DNA methyltransferases of mammals. , 2000, Human molecular genetics.
[68] E. Oakeley. DNA methylation analysis: a review of current methodologies. , 1999, Pharmacology & therapeutics.
[69] B. Dutrillaux,et al. DNA methylation and chromosome instability in breast cancer cell lines , 1999, FEBS Letters.
[70] D. Haber,et al. DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development , 1999, Cell.
[71] S. Baylin,et al. Role of Estrogen Receptor Gene Demethylation and DNA Methyltransferase·DNA Adduct Formation in 5-Aza-2′deoxycytidine-induced Cytotoxicity In Human Breast Cancer Cells* , 1997, The Journal of Biological Chemistry.
[72] Aradhana,et al. Diosgenin--a growth stimulator of mammary gland of ovariectomized mouse. , 1992, Indian journal of experimental biology.
[73] H. Pitot,et al. Characterization of polyribosomes and maturation of ribosomal RNA in hepatoma cells treated with 5-azacytidine. , 1974, Cancer research.
[74] Thomas D. Schmittgen,et al. Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method , 2022 .