Factors affecting the implementation of complex and evolving technologies: multiple case study of intensity-modulated radiation therapy (IMRT) in Ontario, Canada

BackgroundResearch regarding the decision to adopt and implement technological innovations in radiation oncology is lacking. This is particularly problematic since these technologies are often complex and rapidly evolving, requiring ongoing revisiting of decisions regarding which technologies are the most appropriate to support. Variations in adoption and implementation decisions for new radiation technologies across cancer centres can impact patients' access to appropriate and innovative forms of radiation therapy. This study examines the key steps in the process of adopting and implementing intensity modulated radiation therapy (IMRT) in publicly funded cancer centres and identifies facilitating or impeding factors.MethodsA multiple case study design, utilizing document analysis and key informant interviews was employed. Four cancer centres in Ontario, Canada were selected and interviews were conducted with radiation oncologists, medical physicists, radiation therapists, and senior administrative leaders.ResultsEighteen key informants were interviewed. Overall, three centres made fair to excellent progress in the implementation of IMRT, while one centre achieved only limited implementation as of 2009. Key factors that influenced the extent of IMRT implementation were categorized as: 1) leadership, 2) training, expertise and standardization, 3) collaboration, 4) resources, and 5) resistance to change.ConclusionA framework for the adoption and implementation of complex and evolving technologies is presented. It identifies the key factors that should be addressed by decision-makers at specific stages of the adoption/implementation process.

[1]  E. Ferlie,et al.  Interlocking Interactions, the Diffusion of Innovations in Health Care , 2002 .

[2]  Søren M Bentzen,et al.  Randomized controlled trials in health technology assessment: overkill or overdue? , 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[3]  Cedric X. Yu,et al.  Guidance document on delivery, treatment planning, and clinical implementation of IMRT: report of the IMRT Subcommittee of the AAPM Radiation Therapy Committee. , 2003, Medical physics.

[4]  I. Rosen,et al.  Implementing IMRT in clinical practice: a joint document of the American Society for Therapeutic Radiology and Oncology and the American Association of Physicists in Medicine. , 2004, International journal of radiation oncology, biology, physics.

[5]  E. Ferlie,et al.  The Nonspread of Innovations: the Mediating Role of Professionals , 2005 .

[6]  J. Øvretveit,et al.  Improving quality through effective implementation of information technology in healthcare. , 2007, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[7]  Rosaline S Barbour,et al.  Checklists for improving rigour in qualitative research: a case of the tail wagging the dog? , 2001, BMJ : British Medical Journal.

[8]  K Leszczynski,et al.  Organisational standards for the delivery of intensity-modulated radiation therapy in Ontario. , 2009, Clinical oncology (Royal College of Radiologists (Great Britain)).

[9]  J. Coleman,et al.  Medical Innovation: A Diffusion Study. , 1967 .

[10]  R. Yin Case Study Research: Design and Methods , 1984 .

[11]  G. Starkschall,et al.  American Association of Physicists in Medicine Radiation Therapy Committee Task Group 53: quality assurance for clinical radiotherapy treatment planning. , 1998, Medical physics.

[12]  Raghu Garud,et al.  The innovation journey , 1999 .

[13]  J. Staffurth,et al.  A review of the clinical evidence for intensity-modulated radiotherapy. , 2010, Clinical oncology (Royal College of Radiologists (Great Britain)).

[14]  Jean-Pierre Bissonnette,et al.  Error in the delivery of radiation therapy: results of a quality assurance review. , 2005, International journal of radiation oncology, biology, physics.

[15]  Cheng B Saw,et al.  Clinical implementation of intensity-modulated radiation therapy. , 2002, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

[16]  Louise Locock,et al.  No magic targets! Changing clinical practice to become more evidence based. , 2010, Health care management review.

[17]  S. Webb The physical basis of IMRT and inverse planning. , 2003, The British journal of radiology.

[18]  C. Ling,et al.  Planning, delivery, and quality assurance of intensity-modulated radiotherapy using dynamic multileaf collimator: a strategy for large-scale implementation for the treatment of carcinoma of the prostate. , 1997, International journal of radiation oncology, biology, physics.

[19]  M. Finan,et al.  Overcoming technical challenges with robotic surgery in gynecologic oncology , 2010, Surgical Endoscopy.

[20]  Charles B Wilson,et al.  The Future of Food , 2001, BMJ : British Medical Journal.

[21]  P. Northouse Leadership: Theory and Practice , 2000 .

[22]  D. Dearnaley,et al.  The impact of introducing intensity modulated radiotherapy into routine clinical practice. , 2005, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[23]  E. Rogers Diffusion of Innovations , 1962 .

[24]  Matthew B. Miles,et al.  Qualitative Data Analysis: An Expanded Sourcebook , 1994 .

[25]  Kristin Kinney A Systems Approach to Purchasing and Implementing New Technology , 2007, Nursing administration quarterly.

[26]  G. Robert,et al.  Diffusion of innovations in service organizations: systematic review and recommendations. , 2004, The Milbank quarterly.

[27]  Large Discrepancies between Planned and Actually Delivere dose in Imrt of Head and Neck Cancer. A Case Report , 2007, Tumori.

[28]  Sylwia Męcfal Recenzja książki. Robert K. yin, Case Study Research. Design and Methods (fourth Edition), thousand Oaks, CA: Sage Publications, 2009 , 2012 .

[29]  C. Ulrich,et al.  Cancer Pharmacogenomics and Pharmacoepidemiology: Setting a Research Agenda to Accelerate Translation , 2010, Journal of the National Cancer Institute.

[30]  Indra J. Das,et al.  Intensity-Modulated Radiation Therapy Dose Prescription, Recording, and Delivery: Patterns of Variability Among Institutions and Treatment Planning Systems , 2008 .

[31]  J. Williamson,et al.  Quality assurance needs for modern image-based radiotherapy: recommendations from 2007 interorganizational symposium on "quality assurance of radiation therapy: challenges of advanced technology". , 2008, International journal of radiation oncology, biology, physics.

[32]  P. Wallner,et al.  A changing paradigm in the study and adoption of emerging health care technologies: coverage with evidence development. , 2008, Journal of the American College of Radiology : JACR.

[33]  A. Langley Strategies for Theorizing from Process Data , 1999 .

[34]  D. Thwaites,et al.  Vorsprung durch Technik: evolution, implementation, QA and safety of new technology in radiotherapy. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[35]  M. Forster Leadership: Theory and Practice, 3rd Edition , 2007 .

[36]  M. Williams,et al.  The implementation of intensity-modulated radiotherapy in the UK. , 2010, Clinical oncology (Royal College of Radiologists (Great Britain)).

[37]  Louise Locock,et al.  No magic targets! Changing clinical practice to become more evidence based. , 2002, Health care management review.

[38]  L. Collette,et al.  Profile of European radiotherapy departments contributing to the EORTC Radiation Oncology Group (ROG) in the 21st century. , 2008, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[39]  C H Clark,et al.  Implementation of IMRT in the radiotherapy department. , 2003, The British journal of radiology.

[40]  I. Seidman Interviewing as qualitative research : a guide for researchersin education and the social sciences , 1991 .

[41]  M. Young,et al.  Health services research , 2008, Journal of General Internal Medicine.

[42]  Indira Madani,et al.  Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies. , 2008, The Lancet. Oncology.