Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652
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J. Hancox | O. Crociani | A. Arcangeli | H. Witchel | Jules C Hancox | Harry J Witchel | Annarosa Arcangeli | J. Milnes | James T Milnes | Olivia Crociani
[1] W. Gattaz,et al. Cardiovascular effects of fluvoxamine and maprotiline in depressed patients , 2005, European Archives of Psychiatry and Clinical Neuroscience.
[2] Cristina Arias,et al. Spironolactone and Its Main Metabolite, Canrenoic Acid, Block Human Ether-a-Go-Go–Related Gene Channels , 2003, Circulation.
[3] M. Sanguinetti,et al. Position of aromatic residues in the S6 domain, not inactivation, dictates cisapride sensitivity of HERG and eag potassium channels , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[4] Michael C Sanguinetti,et al. Molecular Determinants of Voltage-dependent Human Ether-a-Go-Go Related Gene (HERG) K+ Channel Block* , 2002, The Journal of Biological Chemistry.
[5] M. Jiang,et al. Mapping the Binding Site of a Humanether-a-go-go-related Gene-specific Peptide Toxin (ErgTx) to the Channel's Outer Vestibule* , 2002, The Journal of Biological Chemistry.
[6] Jules C Hancox,et al. Inhibitory actions of the selective serotonin re‐uptake inhibitor citalopram on HERG and ventricular L‐type calcium currents , 2002, FEBS letters.
[7] Dierk Thomas,et al. The antidepressant drug fluoxetine is an inhibitor of human ether-a-go-go-related gene (HERG) potassium channels. , 2002, The Journal of pharmacology and experimental therapeutics.
[8] J. Hancox,et al. Actions of the selective serotonin re-uptake inhibitor fluvoxamine on HERG-mediated potassium current in a mammalian cell line , 2002 .
[9] Stanley Nattel,et al. Dofetilide block involves interactions with open and inactivated states of HERG channels , 2002, Pflügers Archiv - European Journal of Physiology.
[10] I Kodama,et al. Open channel block of HERG K(+) channels by vesnarinone. , 2001, Molecular pharmacology.
[11] B. Lüderitz,et al. Serum Levels and Cardiovascular Effects of Tricyclic Antidepressants and Selective Serotonin Reuptake Inhibitors in Depressed Patients , 2001, Therapeutic drug monitoring.
[12] T J Campbell,et al. HERG K+ channels: friend and foe. , 2001, Trends in pharmacological sciences.
[13] Y. Sawada,et al. A comparative pharmacodynamic study of the arrhythmogenicity of antidepressants, fluvoxamine and imipramine, in guinea pigs. , 2001, Biological & pharmaceutical bulletin.
[14] H. Witchel,et al. Inhibition of HERG potassium channel current by the class 1a antiarrhythmic agent disopyramide. , 2001, Biochemical and biophysical research communications.
[15] Jun Chen,et al. A structural basis for drug-induced long QT syndrome. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Hancox,et al. Familial And Acquired Long QT Syndrome And The Cardiac Rapid Delayed Rectifier Potassium Current , 2000, Clinical and experimental pharmacology & physiology.
[17] T J Campbell,et al. Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel. , 2000, Cardiovascular research.
[18] A. Camm,et al. The potential for QT prolongation and pro-arrhythmia by non-anti-arrhythmic drugs: clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology. , 2000, Cardiovascular research.
[19] M. Gralinski. The assessment of potential for QT interval prolongation with new pharmaceuticals: impact on drug development. , 2000, Journal of pharmacological and toxicological methods.
[20] H. Duff,et al. Molecular determinant of high-affinity dofetilide binding to HERG1 expressed in Xenopus oocytes: involvement of S6 sites. , 2000, Molecular pharmacology.
[21] M. Jiang,et al. Use-dependent 'agonist' effect of azimilide on the HERG channel. , 1999, The Journal of pharmacology and experimental therapeutics.
[22] S. Viskin. Long QT syndromes and torsade de pointes , 1999, The Lancet.
[23] J. Hancox,et al. Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline , 1999, British journal of pharmacology.
[24] Cavero,et al. QT interval prolongation by non-cardiovascular drugs: issues and solutions for novel drug development. , 1999, Pharmaceutical science & technology today.
[25] W. Kübler,et al. Inhibitory effects of the class III antiarrhythmic drug amiodarone on cloned HERG potassium channels , 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.
[26] A. Brown,et al. Blockade of HERG and Kv1.5 by ketoconazole. , 1998, The Journal of pharmacology and experimental therapeutics.
[27] L. Annunziato,et al. Human ether-a-gogo related gene (HERG) K+ channels as pharmacological targets: present and future implications. , 1998, Biochemical Pharmacology.
[28] B. Chait,et al. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. , 1998, Science.
[29] C. January,et al. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature. , 1998, Biophysical journal.
[30] M. Sanguinetti,et al. Role of delayed rectifier potassium channels in cardiac repolarization and arrhythmias , 1997 .
[31] J. Henry. Epidemiology and Relative Toxicity of Antidepressant Drugs in Overdose , 1997, Drug safety.
[32] D M Roden,et al. Rapid inactivation determines the rectification and [K+]o dependence of the rapid component of the delayed rectifier K+ current in cardiac cells. , 1997, Circulation research.
[33] E Wanke,et al. A HERG‐like K+ channel in rat F‐11 DRG cell line: pharmacological identification and biophysical characterization. , 1996, The Journal of physiology.
[34] D. Snyders,et al. High affinity open channel block by dofetilide of HERG expressed in a human cell line. , 1996, Molecular pharmacology.
[35] M. Sanguinetti,et al. Class III antiarrhythmic drugs block HERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides. , 1996, Circulation research.
[36] J. Hancox,et al. A method for making rapid changes of superfusate whilst maintaining temperature at 37 degrees C. , 1996, Pflugers Archiv : European journal of physiology.
[37] G. Robertson,et al. HERG, a human inward rectifier in the voltage-gated potassium channel family. , 1995, Science.
[38] M. Sanguinetti,et al. A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel , 1995, Cell.
[39] J. Ballenger,et al. Cardiovascular effects of imipramine, fluvoxamine, and placebo in depressed outpatients. , 1993, The Journal of clinical psychiatry.
[40] P. Fouet,et al. [Ventricular arrhythmia during fluvoxamine poisoning]. , 1993, Therapie.
[41] J. Feighner,et al. A placebo-controlled inpatient comparison of fluvoxamine maleate and imipramine in major depression. , 1989, International clinical psychopharmacology.
[42] W. Wouters,et al. Acute cardiac effects of fluvoxamine and other antidepressants in conscious rabbits. , 1983, Archives internationales de pharmacodynamie et de therapie.
[43] J. C. Roos,et al. Cardiac effects of antidepressant drugs. A comparison of the tricyclic antidepressants and fluvoxamine. , 1983, British journal of clinical pharmacology.