Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes.

[1]  J. Mullol,et al.  Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis. , 2003, American journal of respiratory and critical care medicine.

[2]  J. Peacock,et al.  Why recent studies relating normal tissue response to individual radiosensitivity might have failed and how new studies should be performed. , 2003, International journal of radiation oncology, biology, physics.

[3]  D. Christiani,et al.  Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk. , 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[4]  D. Albanes,et al.  Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland. , 2003, Cancer letters.

[5]  A. Hajeer,et al.  Association of transforming growth factor beta-1 single nucleotide polymorphisms with radiation-induced damage to normal tissues in breast cancer patients , 2003, International journal of radiation biology.

[6]  N. Russell,et al.  The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia. , 2002, Blood.

[7]  J. Luo,et al.  Effects on sister chromatid exchange frequency of polymorphisms in DNA repair gene XRCC1 in smokers. , 2002, Mutation research.

[8]  J. Overgaard,et al.  Does variability in normal tissue reactions after radiotherapy have a genetic basis--where and how to look for it? , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[9]  A. Begg,et al.  Editorial radiotherapy and oncology 2002: predictive assays for normal tissue damage. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[10]  G. Raaphorst,et al.  Skin fibroblasts in vitro radiosensitivity can predict for late complications following AVM radiosurgery. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[11]  M. Koç,et al.  Effects of tamoxifen on pulmonary fibrosis after cobalt-60 radiotherapy in breast cancer patients. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[12]  E. Vlková,et al.  Polymorphism R25P in the gene encoding transforming growth factor-beta (TGF-beta1) is a newly identified risk factor for proliferative diabetic retinopathy. , 2002, American journal of medical genetics.

[13]  R. Houlston,et al.  Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[14]  J. Peacock,et al.  Normal cellular radiosensitivity in an adult Fanconi anaemia patient with marked clinical radiosensitivity. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[15]  M. Villalobos,et al.  Individualization of radiotherapy in breast cancer patients: possible usefulness of a DNA damage assay to measure normal cell radiosensitivity. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[16]  C. West,et al.  Relationship between residual radiation-induced DNA double-strand breaks in cultured fibroblasts and late radiation reactions: a comparison of training and validation cohorts of breast cancer patients. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[17]  P Vineis,et al.  XRCC1, XRCC3, XPD gene polymorphisms, smoking and (32)P-DNA adducts in a sample of healthy subjects. , 2001, Carcinogenesis.

[18]  P. Jeggo,et al.  Normal cellular radiosensitivity in an adult Fanconi anaemia patient with marked clinical radiosensitivity. , 2001, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[19]  H. Mohrenweiser,et al.  Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. , 2001, Carcinogenesis.

[20]  A. Piazza,et al.  DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case‐control study , 2001, International journal of cancer.

[21]  V. Kosma,et al.  Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk. , 2001, Carcinogenesis.

[22]  J. Hendry,et al.  Genomic instability: potential contributions to tumour and normal tissue response, and second tumours, after radiotherapy. , 2001, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[23]  C. Arlett,et al.  Four radiation hypersensitivity cases and their implications for clinical radiotherapy. , 2000, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[24]  S. Z. Abdel‐Rahman,et al.  The 399Gln polymorphism in the DNA repair gene XRCC1 modulates the genotoxic response induced in human lymphocytes by the tobacco-specific nitrosamine NNK. , 2000, Cancer letters.

[25]  M. Schwarz,et al.  TGF-β1 genotype and accelerated decline in lung function of patients with cystic fibrosis , 2000, Thorax.

[26]  N. Brooks,et al.  Polymorphism of the transforming growth factor-beta 1 gene correlates with the development of coronary vasculopathy following cardiac transplantation. , 2000, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[27]  E. Mark,et al.  Polymorphisms in the Dna Repair Genes Xrcc1 and Ercc2 and Biomarkers of Dna Damage in Human Blood Mononuclear Cells Cross-complementing Group 1) than in 399arg/arg Carriers of Breaks following Base Excision Repair (ber) Resulting From , 2022 .

[28]  D. Bell,et al.  XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. , 1999, Cancer research.

[29]  C. S. Campbell,et al.  Transforming growth factor-beta (TGF-beta1) genotype and lung allograft fibrosis. , 1999, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[30]  E. Bowman,et al.  Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. , 1999, Cancer research.

[31]  P. Hasleton,et al.  Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. , 1998, Transplantation.

[32]  K. Ikeda,et al.  Association of a Polymorphism of the Transforming Growth Factor‐β1 Gene with Genetic Susceptibility to Osteoporosis in Postmenopausal Japanese Women , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[33]  V. Pravica,et al.  Genotyping for polymorphisms in interferon-γ, interleukin-10, transforming growth factor-β1 and tumour necrosis factor-α genes: a technical report , 1998 .

[34]  M. Sporn.  The importance of context in cytokine action. , 1997, Kidney international.

[35]  S M Bentzen,et al.  Relationship between the in vitro radiosensitivity of skin fibroblasts and the expression of subcutaneous fibrosis, telangiectasia, and skin erythema after radiotherapy. , 1996, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[36]  J. Overgaard,et al.  Radiotherapy-related lung fibrosis enhanced by tamoxifen. , 1996, Journal of the National Cancer Institute.

[37]  H. Thames,et al.  Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study. , 1989, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[38]  J. Overgaard.  Effect of misonidazole and hyperthermia on the radiosensitivity of a C3H mouse mammary carcinoma and its surrounding normal tissue. , 1980, British Journal of Cancer.

[39]  H. Hackstein,et al.  Prospective analysis of single nucleotide polymorphisms of the transforming growth factor beta-1 gene in Peyronie's disease. , 2003, The Journal of urology.

[40]  K. Lohman,et al.  Genetic regulation of ionizing radiation sensitivity and breast cancer risk , 2002, Environmental and molecular mutagenesis.

[41]  T. Spector,et al.  Genetic control of the circulating concentration of transforming growth factor type beta1. , 1999, Human molecular genetics.

[42]  H. Thames,et al.  Early and late normal-tissue injury after postmastectomy radiotherapy alone or combined with chemotherapy. , 1989, International journal of radiation biology.

[43]  J. Overgaard,et al.  Some methodological problems in estimating radiobiological parameters from clinical data. Alpha/beta ratios and electron RBE for cutaneous reactions in patients treated with postmastectomy radiotherapy. , 1988, Acta oncologica.

[44]  S. Bentzen,et al.  The value of the NSD formula in equation of acute and late radiation complications in normal tissue following 2 and 5 fractions per week in breast cancer patients treated with postmastectomy irradiation. , 1987, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[45]  R. Wette,et al.  Theoretical considerations on the influence of dose fractionation on effectiveness of radiation therapy. , 1967, National Cancer Institute monograph.