Interventricular dispersion in repolarization causes bifid T waves in dogs with dofetilide-induced long QT syndrome.

[1]  M. J. Janse,et al.  Refractory Period of the Dog's Ventricular Myocardium Following Sudden Changes in Frequency , 1969, Circulation research.

[2]  H. Bazett,et al.  AN ANALYSIS OF THE TIME‐RELATIONS OF ELECTROCARDIOGRAMS. , 1997 .

[3]  A. Moss,et al.  The Long-QT Syndrome , 1992 .

[4]  J. Al-Aama,et al.  Congenital Long QT Syndrome: An Update and Present Perspective in Saudi Arabia , 2013, Front. Pediatr..

[5]  Hitoshi Horigome,et al.  Detection of Extra Components of T Wave by Independent Component Analysis in Congenital Long-QT Syndrome , 2011, Circulation. Arrhythmia and electrophysiology.

[6]  W. Evans.  THE ELECTROCARDIOGRAM OF ALCOHOLIC CARDIOMYOPATHY , 1959, British heart journal.

[7]  H. Wellens,et al.  Repolarizing K+ currents ITO1 and IKs are larger in right than left canine ventricular midmyocardium. , 1999, Circulation.

[8]  Marc A. Vos,et al.  Probing the Contribution of IKs to Canine Ventricular Repolarization: Key Role for &bgr;-Adrenergic Receptor Stimulation , 2003, Circulation.

[9]  Ruben Coronel,et al.  Monophasic action potentials and activation recovery intervals as measures of ventricular action potential duration: experimental evidence to resolve some controversies. , 2006, Heart rhythm.

[10]  E. Aliot,et al.  The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis. , 1988, Progress in cardiovascular diseases.

[11]  C Antzelevitch,et al.  Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. , 1998, Circulation.

[12]  Dimarco Jp,et al.  Cardiovascular drugs. Dofetilide. , 2000 .

[13]  G. Kay,et al.  Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients. , 1983, Journal of the American College of Cardiology.

[14]  R. Lux,et al.  Correlation between in vivo transmembrane action potential durations and activation-recovery intervals from electrograms. Effects of interventions that alter repolarization time. , 1990, Circulation.

[15]  M. Franz.  The Electrical Restitution Curve Revisited: , 2003, Journal of cardiovascular electrophysiology.

[16]  D. Tester,et al.  Effect of clinical phenotype on yield of long QT syndrome genetic testing. , 2006, Journal of the American College of Cardiology.

[17]  M. Rosen,et al.  Developmental changes in IKr and IKs contribute to age-related expression of dofetilide effects on repolarization and proarrhythmia. , 2003, Cardiovascular research.

[18]  Ruben Coronel,et al.  Repolarization Gradients in the Canine Left Ventricle Before and After Induction of Short-Term Cardiac Memory , 2005, Circulation.

[19]  G. Oreto,et al.  Bifid T waves in leads V2 and V3 in children: a normal variant , 2009, Italian journal of pediatrics.

[20]  A. Bass,et al.  The cardiovascular and pharmacokinetic profile of dofetilide in conscious telemetered beagle dogs and cynomolgus monkeys , 2008, British journal of pharmacology.

[21]  Wojciech Zareba,et al.  Spectrum of ST-T–Wave Patterns and Repolarization Parameters in Congenital Long-QT Syndrome: ECG Findings Identify Genotypes , 2000, Circulation.

[22]  Cornelis A. Grimbergen,et al.  Software design for analysis of multichannel intracardial and body surface electrocardiograms , 2002, Comput. Methods Programs Biomed..

[23]  M. Sanguinetti.  Dysfunction of Delayed Rectifier Potassium Channels in an Inherited Cardiac Arrhythmia , 1999, Annals of the New York Academy of Sciences.

[24]  Michael Christiansen,et al.  T wave morphology analysis distinguishes between KvLQT1 and HERG mutations in long QT syndrome. , 2004, Heart rhythm.

[25]  A. Wilde,et al.  The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome. , 2010, Journal of the American College of Cardiology.

[26]  András Varró,et al.  Slow Delayed Rectifier Potassium Current (IKs) and the Repolarization Reserve , 2007, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[27]  Johannes J. Struijk,et al.  Classification of the long-QT syndrome based on discriminant analysis of T-wave morphology , 2006, Computers in Cardiology, 2005.

[28]  M. Sanguinetti,et al.  A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel , 1995, Cell.

[29]  J. .. Abildskov,et al.  Notched T Waves in Young Persons with Central Nervous System Lesions , 1968, Circulation.

[30]  C Antzelevitch,et al.  Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome. , 1997, Circulation.

[31]  A. Moss,et al.  ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome. , 1995, Circulation.

[32]  E. Green,et al.  A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome , 1995, Cell.