Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Genetics of dTDP-Rhamnose Synthetic Enzymes and Development of a Microtiter Plate-Based Screen for Inhibitors of Conversion of dTDP-Glucose to dTDP-Rhamnose
暂无分享,去创建一个
Scott G. Franzblau | Walter H. Lewis | Michael S. Scherman | Michael R. McNeil | S. Franzblau | Yufang Ma | M. McNeil | V. Vissa | Victoria C Jones | Yufang Ma | Varalakshmi D. Vissa | M. Scherman | W. Lewis | Fangqiu Zhang | Richard J. Stern | Wenxin Yan | Victoria Cox Jones | Fangqiu Zhang | R. Stern | Wenxin Yan
[1] P. Reeves,et al. Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid , 1996, Journal of bacteriology.
[2] C. Sasakawa,et al. Nucleotide sequence of the rhamnose biosynthetic operon of Shigella flexneri 2a and role of lipopolysaccharide in virulence , 1994, Journal of bacteriology.
[3] C. Whitfield,et al. Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium. , 1999, Acta crystallographica. Section D, Biological crystallography.
[4] J. Musser,et al. Molecular Genetic Analysis of Nucleotide Polymorphisms Associated with Ethambutol Resistance in Human Isolates ofMycobacterium tuberculosis , 2000, Antimicrobial Agents and Chemotherapy.
[5] A. Elbein,et al. GDP-l-fucose Pyrophosphorylase , 1998, The Journal of Biological Chemistry.
[6] N. Packer,et al. Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster , 1994, Journal of bacteriology.
[7] K. Nikaido,et al. Biosynthesis of thymidine diphosphate L-rhamnose in Escherichia coli K-12. , 1965, Biochimica et biophysica acta.
[8] R. N. Russell,et al. Stereochemical and Mechanistic Studies of CDP-D-glucose Oxidoreductase Isolated from Yersinia pseudotuberculosis , 1991 .
[9] M. Hagmann. Intimate Portraits of Bacterial Nemeses , 2000, Science.
[10] A. Ghose,et al. A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. , 1999, Journal of combinatorial chemistry.
[11] G. Ashwell,et al. Biological mechanisms involved in the formation of deoxysugars. I. Preparation of thymidine diphosphate glucose labeled specifically in carbon 3. , 1965, The Journal of biological chemistry.
[12] E. Thomassen,et al. Altered deoxyribonucleotide pools in P2 eductants of Escherichia coli K-12 due to deletion of the dcd gene , 1976, Journal of bacteriology.
[13] K. Takayama,et al. Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis , 1989, Antimicrobial Agents and Chemotherapy.
[14] A. Maureen Rouhi,et al. TUBERCULOSIS: A TOUGH ADVERSARY: With the tools for a renewed battle in place, development of new weapons to combat the ancient plague should proceed at a rapid pace , 1999 .
[15] C. Ballou,et al. Biosynthesis of mannophosphoinositides by Mycobacterium phlei. Enzymatic acylation of the dimannophosphoinositides. , 1968, The Journal of biological chemistry.
[16] H. Nikaido,et al. The envelope of mycobacteria. , 1995, Annual review of biochemistry.
[17] W. H. Elliott,et al. The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate D-glucose oxidoreductase. , 1968, The Journal of biological chemistry.
[18] J. Goldberg. Genetics of Bacterial Polysaccharides , 1999 .
[19] B. Barrell,et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence , 1998, Nature.
[20] K. Khoo,et al. Mycobacterial lipoarabinomannan: an extraordinary lipoheteroglycan with profound physiological effects. , 1998, Glycobiology.
[21] S. Kornfeld,et al. The enzymatic synthesis of thymidine-linked sugars. II. Thymidine diphosphate L-rhamnose. , 1961, The Journal of biological chemistry.
[22] A. Elbein,et al. Purification to Apparent Homogeneity and Properties of Pig Kidneyl-Fucose Kinase* , 1998, The Journal of Biological Chemistry.
[23] S. Ram,et al. The Latin American ICBG: The first five years , 1999 .
[24] J. Belisle,et al. A novel repeat sequence specific to Mycobacterium tuberculosis complex and its implications. , 1997, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[25] A. Elbein,et al. Purification and properties of mycobacterial GDP-mannose pyrophosphorylase. , 1999, Archives of Biochemistry and Biophysics.
[26] D. Maskell,et al. Bacterial polysaccharide synthesis and gene nomenclature. , 1996, Trends in microbiology.
[27] P. Reeves,et al. Sequence and structural analysis of the rfb (O antigen) gene cluster from a group C1 Salmonella enterica strain. , 1992, Journal of general microbiology.
[28] W. Klaffke,et al. Substrate specificity of native dTDP-D-glucose-4,6-dehydratase: chemo-enzymatic syntheses of artificial and naturally occurring deoxy sugars. , 1996, Carbohydrate research.
[29] M. McNeil,et al. Biosynthetic origin of mycobacterial cell wall galactofuranosyl residues. , 1997, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[30] C. Whitfield,et al. Characterization of dTDP-4-dehydrorhamnose 3,5-Epimerase and dTDP-4-dehydrorhamnose Reductase, Required for dTDP-l-rhamnose Biosynthesis in Salmonella enterica Serovar Typhimurium LT2* , 1999, The Journal of Biological Chemistry.
[31] M. Mcneil. Structure, biosynthesis, and genetics , 1999 .
[32] M. Iseman. Treatment of multidrug-resistant tuberculosis , 1993 .
[33] H. Schweizer,et al. Construction and use of low-copy number T7 expression vectors for purification of problem proteins: purification of mycobacterium tuberculosis RmlD and pseudomonas aeruginosa LasI and RhlI proteins, and functional analysis of purified RhlI. , 1999, Gene.
[34] L. Collins,et al. Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium , 1997, Antimicrobial agents and chemotherapy.
[35] L. Young. Mycobacterium avium complex infection. , 1988, The Journal of infectious diseases.
[36] C. Whitfield,et al. The purification, crystallization and structural elucidation of dTDP-D-glucose 4,6-dehydratase (RmlB), the second enzyme of the dTDP-L-rhamnose synthesis pathway from Salmonella enterica serovar typhimurium. , 2000, Acta crystallographica. Section D, Biological crystallography.
[37] A. M. Rouhi,et al. TUBERCULOSIS : A TOUGH ADVERSARY , 1999 .
[38] B. Wanner,et al. products of Escherichia coli and Mycobacterium tuberculosis , 1999 .
[39] P. Brennan,et al. Major structural features of the cell wall arabinogalactans of Mycobacterium, Rhodococcus, and Nocardia spp. , 1993, Carbohydrate research.
[40] F. Neidhardt,et al. Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology , 1987 .
[41] B. Wanner,et al. Conversion of dTDP-4-keto-6-deoxyglucose to free dTDP-4-keto-rhamnose by the rmIC gene products of Escherichia coli and Mycobacterium tuberculosis. , 1999, Microbiology.
[42] P. Brennan,et al. Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope , 1995, Antimicrobial agents and chemotherapy.
[43] J. Musser,et al. Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. , 1998, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[44] G. Besra,et al. The Mycobacterial Cell Envelope , 1997 .
[45] D E Snider,et al. Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. , 1995, JAMA.
[46] C. Whitfield,et al. Purification, crystallization and preliminary structural studies of dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase (RmlC), the third enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar typhimurium. , 1999, Acta crystallographica. Section D, Biological crystallography.
[47] D. Cohn. Treatment of multidrug-resistant tuberculosis. , 1995, The Journal of hospital infection.
[48] C. Barry,et al. New horizons in the treatment of tuberculosis. , 1997, Biochemical pharmacology.
[49] F. Lombardo,et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. , 2001, Advanced drug delivery reviews.
[50] N. Moran,et al. WHO issues another gloomy tuberculosis report , 1996, Nature Medicine.
[51] J. Naismith,et al. RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase , 2000, Nature Structural Biology.
[52] J. Belisle,et al. Determination of the pathway for rhamnose biosynthesis in mycobacteria: cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase. , 1997, Microbiology.