Actin cable distribution and dynamics arising from cross-linking, motor pulling, and filament turnover

A computational model of actin cables in fission yeast is presented that includes polymerization, severing, cross-linking, and motor pulling. Results reproduce observations in wild-type cells and cells lacking myosin V and are compared to images of cells overexpressing α-actinin. Formin clustering at cell tips is predicted to promote cable formation.

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