Prognosis of surgically treated chronic aortic valve disease. Predictive indicators of early postoperative risk and long-term survival, based on 439 cases.

The study concerns 439 patients having isolated chronic aortic valve disease (248 having pure or predominant calcific stenosis, 65 having stenosis and regurgitation, and 126 having aortic regurgitation). The operations began in 1968, and the survivors have been re-examined every year, with an average follow-up of 44.2 months. Average age at operation was 55 years (range 14 to 78). Patients in the stenosis group were significantly older (59.7 years) than those in the mixed disease group (54.8 years) or the regurgitation group (45.8 years) (p

[1]  Michael V. Green,et al.  Exercise-induced left ventricular dysfunction in symptomatic and asymptomatic patients with aortic regurgitation: assessment with radionuclide cineangiography. , 1978, The American journal of cardiology.

[2]  W. Gaasch,et al.  Chronic Aortic Regurgitation: The Effect of Aortic Valve Replacement on Left Ventricular Volume, Mass and Function , 1978, Circulation.

[3]  Michael V. Green,et al.  Left ventricular function in aortic stenosis: Response to exercise and effects of operation , 1978 .

[4]  W. Haenszel,et al.  Statistical aspects of the analysis of data from retrospective studies of disease. , 1959, Journal of the National Cancer Institute.

[5]  D. McGoon,et al.  Prognosis of aortic valve replacement in relation to the preoperative heart size. , 1973, The Journal of thoracic and cardiovascular surgery.

[6]  D. Stewart,et al.  Left Ventricular Function Before and Following Aortic Valve Replacement , 1977, Circulation.

[7]  J. Hirshfeld,et al.  Indices Predicting Long‐term Survival after Valve Replacement in Patients with Aortic Regurgitation and Patients with Aortic Stenosis , 1974, Circulation.

[8]  N. Breslow Covariance analysis of censored survival data. , 1974, Biometrics.

[9]  M. Schlepper,et al.  Recovery from myocardial failure after aortic valve replacement. , 1978, The Journal of thoracic and cardiovascular surgery.

[10]  M. Yacoub,et al.  Influence of preoperative left ventricular function on results of homograft replacement of the aortic valve for aortic stenosis. , 1979, The American journal of cardiology.

[11]  P. Reddy,et al.  Effect of Preoperative Ejection Fraction on Survival and Hemodynamic Improvement Following Aortic Valve Replacement , 1978, Circulation.

[12]  R. Ellison,et al.  Thirteen year experience with aortic valve replacement. , 1977, The American journal of cardiology.

[13]  B. Pasternack,et al.  Factors Influencing Long‐Term Survival After Isolated Aortic Valve Replacement , 1974, Circulation.

[14]  J. Copeland,et al.  Long-term follow-up after isolated aortic valve replacement. , 1977, The Journal of thoracic and cardiovascular surgery.

[15]  S. Rahimtoola,et al.  Severe Aortic Stenosis with Impaired Left Ventricular Function and Clinical Heart Failure: Results of Valve Replacement , 1978, Circulation.

[16]  H. Loeb,et al.  Reversal of advanced left ventricular dysfunction following aortic valve replacement for aortic stenosis. , 1977, The Annals of thoracic surgery.

[17]  S. Rahimtoola,et al.  Effects of successful, uncomplicated valve replacement on ventricular hypertrophy, volume, and performance in aortic stenosis and in aortic incompetence. , 1978, The Journal of thoracic and cardiovascular surgery.

[18]  M. Yacoub,et al.  Influence of preoperative left ventricular function on results of homograft replacement of the aortic valve for aortic regurgitation. , 1979, The Journal of thoracic and cardiovascular surgery.

[19]  D. Harrison,et al.  Evaluation of Left Ventricular Function in Patients with Aortic Regurgitation Using Afterload Stress , 1976, Circulation.

[20]  R. Wallace,et al.  Isolated replacement of the aortic valve with the Starr-Edwards prosthesis. A 9 year review. , 1975, The Journal of thoracic and cardiovascular surgery.