Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations
暂无分享,去创建一个
John D. Minna | David S. Shames | Yang Xie | Woochang Lee | Ignacio I. Wistuba | Mitsuo Sato | Adi F. Gazdar | J. Minna | I. Wistuba | A. Gazdar | J. Shay | J. DiMaio | Hao Tang | Yang Xie | Woochang Lee | Mitsuo Sato | R. Ramirez | D. Shames | J. Larsen | B. Gao | Jerry W. Shay | Han Sun | Jill E. Larsen | Boning Gao | Hao Tang | Maithili P. Dalvi | Ruben D. Ramirez | John Michael DiMaio | Han Sun | B. Gao | Jill Larsen
[1] J. Minna,et al. Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer , 2013, Oncogene.
[2] T. Itoh,et al. Oncogene-mediated human lung epithelial cell transformation produces adenocarcinoma phenotypes in vivo. , 2011, Cancer research.
[3] John V Heymach,et al. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. , 2012, Journal of the National Cancer Institute.
[4] Marshall W. Anderson,et al. EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. , 2007, Cancer research.
[5] Brian H. Dunford-Shore,et al. Somatic mutations affect key pathways in lung adenocarcinoma , 2008, Nature.
[6] J. Minna,et al. Infrequent Mutation of the hBUB1 and hBUBR1 Genes in Human Lung Cancer , 2000, Japanese journal of cancer research : Gann.
[7] A. Gazdar,et al. Lung cancer in never smokers — a different disease , 2007, Nature Reviews Cancer.
[8] W. Hahn,et al. Transformation of Human and Murine Fibroblasts without Viral Oncoproteins , 2005, Molecular and Cellular Biology.
[9] Toshihide Tsuda,et al. The TP53 gene, tobacco exposure, and lung cancer , 2003, Human mutation.
[10] W. Hahn,et al. Immortalization and transformation of primary human airway epithelial cells by gene transfer , 2002, Oncogene.
[11] Robert Gentleman,et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer , 2012, Nature Genetics.
[12] John D Minna,et al. Molecular biology of lung cancer: clinical implications. , 2002, Clinics in chest medicine.
[13] J. Minna,et al. A Translational View of the Molecular Pathogenesis of Lung Cancer , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[14] S. Lowe,et al. Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a , 1997, Cell.
[15] J. Minna,et al. Multipotent Capacity of Immortalized Human Bronchial Epithelial Cells , 2011, PloS one.
[16] M. Jackson,et al. TGF-β signaling engages an ATM-CHK2-p53–independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells , 2011, Proceedings of the National Academy of Sciences.
[17] J. Pollack,et al. Immortalization of Human Bronchial Epithelial Cells in the Absence of Viral Oncoproteins , 2004, Cancer Research.
[18] M. Sporn,et al. Type beta transforming growth factor is the primary differentiation-inducing serum factor for normal human bronchial epithelial cells. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[19] Luc Girard,et al. Lung cancer cell lines as tools for biomedical discovery and research. , 2010, Journal of the National Cancer Institute.
[20] Aubrey E. Hill,et al. Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation. , 2002, Cancer research.
[21] C. Harris,et al. Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. , 1988, Cancer research.
[22] Angela N. Brooks,et al. Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing , 2012, Cell.
[23] Laura A. Sullivan,et al. Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. , 2010, Cancer research.
[24] J. Minna,et al. Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. , 2006, Cancer research.
[25] P. M. Campbell,et al. K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling. , 2007, Cancer research.
[26] J. Minna,et al. A three-dimensional model of differentiation of immortalized human bronchial epithelial cells. , 2006, Differentiation; research in biological diversity.
[27] Robert A. Weinberg,et al. Creation of human tumour cells with defined genetic elements , 1999, Nature.
[28] M. Cole,et al. E-cadherin repression contributes to c-Myc-induced epithelial cell transformation , 2007, Oncogene.
[29] Igor Jurisica,et al. Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study , 2008, Nature Medicine.
[30] W. Hahn,et al. Involvement of PP2A in viral and cellular transformation , 2005, Oncogene.
[31] W. Hahn,et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. , 2001, Genes & development.
[32] J. Minna,et al. SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner. , 2011, Cancer research.
[33] Luc Girard,et al. Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer , 2003, Oncogene.
[34] Luzhe Sun,et al. Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells , 2012, Molecular biology of the cell.
[35] J. Minna,et al. NCI‐navy medical oncology branch cell line data base , 1996, Journal of cellular biochemistry. Supplement.
[36] Jingwei Cheng,et al. Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens. , 2009, Seminars in cancer biology.
[37] S. Jones,et al. Many roads lead to oncogene-induced senescence , 2008, Oncogene.
[38] Li Ding,et al. Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers , 2012, Cell.
[39] S. Adam,et al. A network of genetic events sufficient to convert normal human cells to a tumorigenic state. , 2005, Cancer research.