Integrated analytical sensors: the use of the TISPR-1 as a biosensor

Abstract The TISPR-1 integrated surface plasmon resonance (SPR) sensor has features that make it ideal for use in a distributed sensor environment. This sensor, combined with simple bio-films, is shown to be capable of a wide variety of bio-assays. Data for a direct-binding assay for creatine kinase MB (CK-MB), for a displacement assay for dinitrophenol-glycine (DNP-GLY) and a competition assay for trinitrotoluene (TNT) are presented. Also, current and projected TISPR-1 sensor system limits of detection are discussed.

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